Results 101 to 110 of about 46,705 (226)

Intrapleural Instillation of Sodium Bicarbonate versus Urokinase in Management of Complicated Pleural Effusion: A Comparative Cohort Study

International Journal of General Medicine, 2022
Niveen E Zayed,1 Karim El Fakharany,2 Mohammed Mehriz Naguib Abozaid1 1Department of Chest Disease, Faculty of Medicine, Zagazig University, Zagazig City, Egypt; 2Department of Cardiothoracic Surgery, Faculty of Medicine, Zagazig University, Zagazig City,
Zayed NE, El Fakharany K, Mehriz Naguib Abozaid M   +2 more
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, Volume 20, Issue 11, Page 2955-2973, November 2026.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

A matters arising: discussion on urokinase dosing and individualized treatment strategies in the TRUST trial

BMC Medicine
This matters arising addresses the recently published article in BMC Medicine by Tao Y et al., entitled “Effect of intravenous urokinase vs best medicine treatment on functional outcome for patients with acute minor stroke (TRUST): a randomized ...
Yue Qiao, Xunming Ji, Wenbo Zhao
doaj   +1 more source

Role of Urokinase in Delayed Presentation of Deep Vein Thrombosis: Single Center Experience

Indian Journal of Vascular and Endovascular Surgery
Background: Deep vein thrombosis (DVT) is a common and potentially devastating condition that can lead to permanent disability with significant morbidity and mortality.
Kesha Shah, Apurva Shah, Sourabh Mittal, Sunil Dixit, Anil Sharma   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, Volume 20, Issue 11, Page 2569-2583, November 2026.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Distribution of Urokinase Among the Common Mammals

, 1957
Urokinase, a principle capable of activating profibrinolysin to fibrinolysin, has been found in the urine of the cat, rat, cow, rabbit, man, dog and hamster.
Stanley R. Mohler, D. Robert Celander, M. Mason Guest   +2 more
core   +1 more source

Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments

Advanced Science, Volume 13, Issue 61, 3 November 2026.
Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang, Pan Liu, Jie Lei, Shuchang Peng, Qiu Chen, Wei Guan, Yizhou Zhu, Gang Liu, Xiaobo Feng, Cao Yang, Lei Tan   +10 more
wiley   +1 more source

Urokinase prophylactic anticoagulation in children with nephrotic syndrome: a multicenter retrospective cohort study

BMC Nephrology
Objective To analyze the clinical effect of urokinase on the prevention of thrombosis in children with primary nephrotic syndrome. Methods A total of 370 children diagnosed with primary nephrotic syndrome (PNS) in the Children’s Hospital of Soochow ...
Zhen Wang, Nan Wang, Ruyue Chen, Hanyun Tang, Qiang Lin, Xiaozhong Li   +5 more
doaj   +1 more source

A covalent peptide engager approach to equip immunotherapeutic monoclonal and pan IgG serum antibodies with new tumour‐targeting function

British Journal of Pharmacology, Volume 183, Issue 22, Page 6685-6703, November 2026.
Abstract Background and Purpose Site‐specific antibody modification is a useful chemical strategy to elaborate antibody therapeutic function. Conventional lysine‐ or cysteine‐based conjugation methods generate heterogeneous products, while protein engineering approaches are resource‐intensive.
Karolina Krygier, Sandra Szu‐Wei Hwang, Anthony F. Rullo   +2 more
wiley   +1 more source

Urokinase and the intestinal mucosa: evidence for a role in epithelial cell turnover

, 1998
Background—The functions of urokinase in intestinal epithelia are unknown.Aims—To determine the relation of urokinase expressed by intestinal epithelial cells to their position in the crypt-villus/surface axis and of mucosal urokinase activity to ...
C F Finch, O Rosella, P R Gibson, G P Young, D H Barkla, V Albert, I Birchall   +6 more
core   +1 more source