Results 81 to 90 of about 46,705 (226)
This study was a retrospective analysis of the efficacy of thrombectomy plus local catheter-directed thrombolysis (CDT) for the treatment of lower extremity deep venous thrombosis (LDVT).
Wang Wenli +3 more
doaj +1 more source
ABSTRACT Background Hemodialysis access thrombosis is the primary cause of access failure. Thrombus removal is an effective strategy to restore access function. Although both open surgical and endovascular procedures enable thrombus clearance, endovascular thrombus reduction therapy is widely adopted in clinical practice for this condition due to its ...
Lin Li +5 more
wiley +1 more source
ABSTRACT Introduction The plasminogen activating (PA) system has a multitude of functions such as wound healing, proteolytic activity, collagen degradation and cell growth, and the role of the urokinase plasminogen activator/urokinase plasminogen activator receptor (uPA/uPAR) system has been studied in many disease states.
Ahmed Khudhur +6 more
wiley +1 more source
Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley +1 more source
Urokinase receptor mediates mechanical force transfer across the cell surface
The tripartite complex formed by the urokinase receptor, urokinase, and its inhibitor is an enzymatic system that controls plasmin formation involved in degradation of extracellular matrix proteins.
N. Wang +4 more
core +1 more source
Treatment with a Urokinase Receptor-derived Cyclized Peptide Improves Experimental Colitis by Preventing Monocyte Recruitment and Macrophage Polarization [PDF]
Leukocyte migration across the blood barrier and into tissues represents a key process in the pathogenesis of inflammatory bowel diseases. The urokinase receptor (urokinase-type plasminogen activator receptor) is a master regulator of leukocyte ...
Fonteyne, Philippe +29 more
core +1 more source
Jin Shang,1 Juan Li,2 Qing Bai,2 Yongmei Wang,2 Hongjian Chen,1 Shunxu Li2 1Department of Ultrasound, The Third People’s Hospital of Yunnan, Kunming, People’s Republic of China; 2Department of Obstetrics, The Third People’s Hospital of Yunnan, Kunming ...
Shang J +5 more
doaj
Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw +4 more
wiley +1 more source
Coagulation and fibrinolysis in rheumatoid arthritis Part 2: Urokinase treatment [PDF]
Coagulation and fibrinolysis of RA patients were examined and Hypercoagulation and secondary fibrinolysis were found. On the basis of these findings, fibrinolytic treatment with 24,000 ploug units of urokinase was performed.
Morimoto, Chuichi
core

