Numerical study of cancer cell invasion dynamics using adaptive mesh refinement: the urokinase model [PDF]
arXiv, 2014 In the present work we investigate the chemotactically and proteolytically driven tissue invasion by cancer cells. The model employed is a system of advection-reaction-diffusion equations that features the role of the serine protease urokinase-type plasminogen activator.
Hellmann, Nadja +4 more
arxiv +2 more sources
Safety and efficacy of tirofiban after intravenous thrombolysis with urokinase in patients with acute ischemic stroke [PDF]
Frontiers in NeurologyIntroductionTirofiban combined with alteplase thrombolysis or endovascular therapy has been proven to improve the prognosis of patients with acute ischemic stroke (AIS).
Dian Qu +7 more
doaj +2 more sources
Efficacy of YL-1 hematoma crushing needle combined with hematoma drainage in intracerebral hemorrhage treatment [PDF]
Frontiers in MedicineObjectiveEarly craniotomy evacuation in hematoma surgery does not significantly improve the prognosis of patients with spontaneous intracerebral hemorrhage (ICH).
Xianyong Chen +5 more
doaj +2 more sources
Intravenous Thrombolysis with Urokinase for Acute Ischemic Stroke [PDF]
Brain SciencesBackground: Intravenous thrombolysis is one of the most effective therapies for the treatment of acute ischemic stroke (AIS), with urokinase offering a cost-effective alternative to newer agents like alteplase and tenecteplase, especially in resource ...
Yue Qiao +5 more
doaj +2 more sources
Non-Surgical Bleeding and Transurethral Resection of the Prostate (TURP) Syndrome after TURP Surgery: A Case Report and Literature Review [PDF]
PathophysiologyPatients undergoing transurethral resection of the prostate (TURP) surgery can develop TURP syndrome and post-TURP bleeding. Post-TURP bleeding can be surgical, from arteries or venous sinuses, or non-surgical, due to coagulopathy preventing clot ...
Akram M. Eraky +4 more
doaj +2 more sources
Soluble Urokinase Receptor (SuPAR) in COVID-19-Related AKI.
Journal of the American Society of Nephrology, 2020 BACKGROUND AKI commonly occurs in patients with coronavirus disease 2019 (COVID-19). Its pathogenesis is poorly understood. The urokinase receptor system is a key regulator of the intersection between inflammation, immunity, and coagulation, and soluble ...
T. Azam +26 more
semanticscholar +1 more source
Frontiers in Neurology, 2021 Background: Intravenous thrombolysis with alteplase benefits eligible patients with acute ischemic stroke. However, in some countries such as China, alteplase may be too expensive for low-income patients, and also for regions with low economic ...
Rongrong Zhang +11 more
doaj +1 more source
Transcriptional regulation of the urokinase receptor (u-PAR) - A central molecule of invasion and metastasis [PDF]
, 2003 The phenomenon of tumor-associated proteolysis has been acknowledged as a decisive step in the progression of cancer. This short review focuses on the urokinase receptor (u-PAR), a central molecule involved in tumor-associated invasion and metastasis ...
Behrendt N. +31 more
core +1 more source
Fibrinolysis versus thoracoscopy: Comparison of results in empyema management in the child
Annals of Thoracic Medicine, 2022 OBJECTIVE: The objective of this study is to compare the outcome of treatment with drainage and urokinase (UK) versus thoracoscopy (TS) in pleural empyema secondary to complicated pneumonia.
Maria Rosa Ibarra Rodriguez +5 more
doaj +1 more source
Frontiers in Oncology, 2018 The plasminogen activator (PA) system is an extracellular proteolytic enzyme system associated with various physiological and pathophysiological processes.
Niaz Mahmood, C. Mihalcioiu, S. Rabbani
semanticscholar +1 more source