A matters arising: discussion on urokinase dosing and individualized treatment strategies in the TRUST trial [PDF]
BMC MedicineThis matters arising addresses the recently published article in BMC Medicine by Tao Y et al., entitled “Effect of intravenous urokinase vs best medicine treatment on functional outcome for patients with acute minor stroke (TRUST): a randomized ...
Yue Qiao, Xunming Ji, Wenbo Zhao
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Free flap salvage via direct urokinase injection into thrombosed veins: a case report [PDF]
Case Reports in Plastic Surgery & Hand SurgeryIntraoperative use of urokinase is a recognized method for salvaging compromised free flaps. However, protocols for dosage and administration vary, and no consensus exists regarding the optimal technique.
Masanobu Hayashi +5 more
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Low-dose urokinase thrombolysis combined with papaverine for central retinal artery occlusion: a preliminary exploration of efficacy and safety [PDF]
Frontiers in NeurologyObjectiveTo investigate the efficacy and safety of low-dose urokinase combined with papaverin administered via superselective ophthalmic artery thrombolysis in patients with non-arteritic central retinal artery occlusion (CRAO).MethodsA retrospective ...
Hongyan Sun +10 more
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A comparative study of anticoagulation combined with different catheter-directed thrombolysis strategies (urokinase catheter-directed vs. alteplase infusion) in the treatment of intermediate-risk pulmonary embolism [PDF]
Frontiers in Cardiovascular MedicineObjectiveTo compare the clinical efficacy and safety of anticoagulation combined with catheter-directed urokinase (UK) thrombolysis vs. anticoagulation combined with catheter-directed alteplase (rt-PA) infusion thrombolysis in patients with intermediate ...
Jinqi Huang, Qihong Chen
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A case of complicated parapneumonic pleural effusion caused by paragonimus infection in a child was successfully treated by intrapleural injection of urokinase: a case report and literature review [PDF]
Frontiers in PediatricsObjectiveThe clinical data of a child with complex parapneumonic effusion (PPE) caused by pneumofluke infection were analyzed, and the diagnosis and treatment of the disease were discussed through literature review.
Yangyi Shi, Yan Li, Yu Hu
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Efficacy and safety of catheter-directed thrombolytic therapy of alteplase and urokinase for the treatment of deep vein thrombosis: a Meta-analysis [PDF]
Yixue xinzhi zazhi, 2023 Objective To systematically review the effectiveness and safety of cathe-ter-directed thrombolytic therapy (CDT) using alteplase and urokinase in the treatment of deep vein thrombosis (DVT) in the lower extremities.Method PubMed, The Cochrane Library ...
Hong-Yan LI +6 more
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Fibrinolysis with Lower Dose Urokinase in Patients with Complicated Parapneumonic Effusion [PDF]
Tuberculosis and Respiratory Diseases, 2021 Background Intrapleural urokinase is one of the most widely used fibrinolytic agents in the treatment of complicated parapneumonic effusion (CPPE). However, little research has been performed on the optimal urokinase dosage.
Seul Lee +8 more
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Neurologia Medico-Chirurgica, 2022 Delayed cerebral vasospasms after subarachnoid hemorrhage (SAH) are a risk factor for poor prognosis after successful treatment of ruptured intracranial aneurysms.
Arata NAGAI +5 more
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Fibrinolysis regulation by platelets retaining plasminogen and tissue-type plasminogen activator on their surface [PDF]
The Ukrainian Biochemical Journal, 2019 Platelets play a key role in hemostasis as cofactors of thrombin generation, fibrin polymerization centers, and initiators of clot retraction, while their ability to modulate clot dissolution remains less understood.
T. Grinenko +4 more
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Frontiers in Neurology, 2021 Background: Intravenous thrombolysis with alteplase benefits eligible patients with acute ischemic stroke. However, in some countries such as China, alteplase may be too expensive for low-income patients, and also for regions with low economic ...
Rongrong Zhang +11 more
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