Results 131 to 140 of about 27,231 (235)

Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma

eFood, Volume 7, Issue 3, June 2026.
Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie, Wei Fang, Zean Song, Zhang Yu, Ying Zhu, Shaoping Liu   +5 more
wiley   +1 more source

Urokinase receptor expression is upregulated by cell culture sparsity in breast cancer cell line BT20

, 1999
Background: The processes of tumour cell migration and invasion are enhanced by urokinase activity mediated by the urokinase receptor on the cell surface.
Yellowlees, D., Wood, N. J., Donnelly, P. K., Li, Y.   +3 more
core  

Effect of Anthocyanin‐Rich New Zealand Blackcurrant on Tumour Necrosis Factor‐α–Induced Plasminogen Activator Inhibitor‐1 Release in Airway Epithelial Cells: A Preliminary Study

Phytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
Pretreatment with New Zealand blackcurrant anthocyanins nonsignificantly reduced TNF‐α–induced PAI‐1 release in bronchial epithelial cells. The small sample size may have influenced the lack of statistical significance. This study provides preliminary evidence of possible effects of NZBC anthocyanins on PAI‐1 secretion but warrants further extensive ...
Madiha Ajaz, Ayesha Zahid, Rati Jani, Lada Vugic, Indu Singh, Natalie Shilton   +5 more
wiley   +1 more source

The Urokinase Receptor: A Multifunctional Receptor in Cancer Cell Biology. Therapeutic Implications. [PDF]

Int J Mol Sci, 2021
Li Santi A, Napolitano F, Montuori N, Ragno P.   +3 more
europepmc   +1 more source

The intact urokinase receptor is required for efficient vitronectin binding: receptor cleavage prevents ligand interaction

, 1997
The urokinase receptor (uPAR) is a receptor for both urokinase plasminogen activator (uPA) and the adhesion protein vitronectin. There are two forms of cell surface-bound uPAR; intact uPAR and a cleaved form, uPAR(2+3), which is formed by uPA-catalyzed ...
Preissner, Klaus T, Gunilla Høyer-Hansen, Behrendt, Niels, Ploug, Michael, Keld Danø, Niels Behrendt, Danø, Keld, Michael Ploug, Klaus T Preissner, Høyer-Hansen, Gunilla   +9 more
core   +1 more source

Excessive hypercholesterolaemia during pregnancy as a risk factor for endothelial dysfunction in pre‐eclampsia

The Journal of Physiology, Volume 604, Issue 11, Page 4302-4317, 1 June 2026.
Abstract figure legend Excessive hypercholesterolaemia during pregnancy impairs maternal endothelial function, which, in turn, drives the development of pre‐eclampsia and may also contribute to the increased risk of later‐life cardiovascular disease in women.
Amanda A. de Oliveira, Floor Spaans, Christy‐Lynn M. Cooke, Sandra T. Davidge   +3 more
wiley   +1 more source

BIOCHEMICAL MARKERS OF ENDOTHELIAL DYSFUNCTION AND HEMOSTASIS IN ATHEROSCLEROSIS AND THE GENES RESPONSIBLE FOR THEIR REGULATION

Атеросклероз, 2017
The review systematized modern concepts of markers of endothelial dysfunction and disorders of hemostasis (asymmetric dimethylarginine, endothelin 1, adhesive ICAM and VCAM molecules, apolipoproteins, antithrombin III, receptor of urokinase plasminogen ...
E. V. Stryukova, Yu. I. Ragino, V. N. Maksimov   +2 more
doaj  

Soluble Urokinase Receptor as a Promising Marker for Early Prediction of Outcome in COVID-19 Hospitalized Patients. [PDF]

J Clin Med, 2021
Napolitano F, Di Spigna G, Vargas M, Iacovazzo C, Pinchera B, Spalletti Cernia D, Ricciardone M, Covelli B, Servillo G, Gentile I, Postiglione L, Montuori N.   +11 more
europepmc   +1 more source

Related Article from Urokinase-Type Plasminogen Activator Receptor: A Beacon of Malignancy?

, 2008
Related Article from Urokinase-Type Plasminogen Activator Receptor: A Beacon of ...
Ronny Drapkin (130800), Adam Clauss (14974395), Steven Skates (10033747)   +2 more
core   +1 more source

Plasminogen Activator Inhibitor‐1 is Internalized by Endothelial Cells via A Pinocytosis‐Like Mechanism and Evades Degradation

The FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Plasminogen activator inhibitor 1 (PAI1) is a secreted protein that also regulates intracellular processes, such as inhibition of endothelial nitric oxide synthase (eNOS). Interaction between Plasminogen Activators (PA) and PAI1 results in a covalent linkage.
Molly McAdow, Gjina Ahmetaj, Rachel Hauschel, Anne Eichmann, William Sessa   +4 more
wiley   +1 more source