Results 81 to 90 of about 25,610 (245)

Soluble urokinase plasminogen activator receptor predicts mortality in exacerbated COPD

Respiratory Research, 2018
Background The inflammatory biomarker soluble urokinase plasminogen activator receptor (suPAR) is elevated in severe acute and chronic medical conditions and has been associated with short-term mortality.
Nina S. Godtfredsen, Ditte V. Jørgensen, Kristoffer Marsaa, Charlotte S. Ulrik, Ove Andersen, Jesper Eugen-Olsen, Line J. H. Rasmussen   +6 more
doaj   +1 more source

Soluble Urokinase Plasminogen Activator Receptor: Genetic Variation and Cardiovascular Disease Risk in Black Adults [PDF]

, 2021
Nels C. Olson, Laura M. Raffield, Anne H. Moxley, Tyne W. Miller‐Fleming, Paul L. Auer, Nora Franceschini, Debby Ngo, Timothy A. Thornton, Ethan M. Lange, Yun Li, Deborah A. Nickerson, Neil A. Zakai, Robert E. Gerszten, Nancy J. Cox, Adolfo Correa, Karen L. Mohlke, Alexander P. Reiner   +16 more
openalex   +1 more source

Melatonin and the Dental Pulp: A Scoping Review

International Endodontic Journal, EarlyView.
ABSTRACT Background In general medicine, melatonin is known to enhance wound healing and promote stem cell differentiation. Its potential relevance in endodontics, however, remains underexplored. Objectives This scoping review aimed to systematically assess the available evidence on the effects of melatonin (a) on dental pulp tissue and (b) on human ...
Jasmin Schäfer, Konrad Kleszczynski, Edgar Schäfer   +2 more
wiley   +1 more source

Establishment of human patient-derived endometrial cancer xenografts in NOD scid gamma mice for the study of invasion and metastasis.

PLoS ONE, 2014
ObjectiveMost endometrial cancers are detected early and have a good prognosis, while some endometrial cancers are highly invasive, metastasize early, and respond suboptimally to therapy.
Kenji Unno, Masanori Ono, Abigail D Winder, Kruti P Maniar, Ajit S Paintal, Yanni Yu, Jian-Jun Wei, John R Lurain, J Julie Kim   +8 more
doaj   +1 more source

Excessive hypercholesterolaemia during pregnancy as a risk factor for endothelial dysfunction in pre‐eclampsia

The Journal of Physiology, EarlyView.
Abstract figure legend Excessive hypercholesterolaemia during pregnancy impairs maternal endothelial function, which, in turn, drives the development of pre‐eclampsia and may also contribute to the increased risk of later‐life cardiovascular disease in women.
Amanda A. de Oliveira, Floor Spaans, Christy‐Lynn M. Cooke, Sandra T. Davidge   +3 more
wiley   +1 more source

Plasminogen activator urokinase receptor as a diagnostic and prognostic biomarker in type 2 diabetic patients with cardiovascular disease. [PDF]

J Cardiovasc Thorac Res, 2023
Mohammed MS, Ahmed HS.
europepmc   +1 more source

N-Formyl Peptide Receptors Induce Radical Oxygen Production in Fibroblasts Derived From Systemic Sclerosis by Interacting With a Cleaved Form of Urokinase Receptor [PDF]

, 2018
Filomena Napolitano, Francesca Wanda Rossi, Ada Pesapane, Silvia Varricchio, Gennaro Ilardi, Massimo Mascolo, Stefania Staibano, Antonio Lavecchia, Pia Ragno, Carmine Selleri, Gianni Marone, Marco Matucci‐Cerinic, Amato de Paulis, Nunzia Montuori   +13 more
openalex   +1 more source

Isoquercetin and Zafirlukast Cooperatively Suppress Tumor Growth and Thromboinflammatory Signaling in a Xenograft Model of Ovarian Cancer

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Treatment using either the thiol isomerase inhibitor isoquercetin or zafirlukast lowers tissue factor levels, decreases VEGF, inhibits PD‐L1, and TMEM176B in a xenograft model of ovarian cancer. A combination of the two agents, at threefold lower concentrations than either drug, significantly enhanced the inhibition further, suggesting a dual action of
Justine A. Keovilay, Jason W. Hoskins, Jean‐Pierre Kinet, Thomas C. Lines, Daniel R. Kennedy   +4 more
wiley   +1 more source

The Blood Urokinase System in Patients with Seasonal Allergic Rhinitis and Concomitant Seasonal Asthma during Pollen Season

European Journal of Inflammation, 2011
It is well known that the fibrinolytic system actively participates in inflammatory processes. To investigate the role of the urokinase system in atopic allergy, we assessed circulating levels of urokinase-type plasminogen activator (uPA) and its soluble
A. Kasperska-Zajac, E. Czecior, A. Grzanka, E. Machura, M. Misiolek   +4 more
doaj   +1 more source

Redrawing Urokinase Receptor (uPAR) Signaling with Cancer Driver Genes for Exploring Possible Anti-Cancer Targets and Drugs. [PDF]

Pharmaceuticals (Basel), 2023
Chang YC, Wu CZ, Cheng CW, Chen JS, Chang LC.   +4 more
europepmc   +1 more source