Results 31 to 40 of about 3,148 (181)

Isolation of Human Intestinal Bacteria Capable of Producing the Bioactive Metabolite Isourolithin A from Ellagic Acid

open access: yesFrontiers in Microbiology, 2017
Urolithins are intestinal microbial metabolites produced from ellagitannin- and ellagic acid-containing foods such as walnuts, strawberries, and pomegranates.
María V. Selma   +7 more
doaj   +1 more source

Interactions between Gut Microbiota and Polyphenols: New Insights into the Treatment of Fatigue

open access: yesMolecules, 2022
Fatigue seriously affects people’s work efficiency and quality of life and has become a common health problem in modern societies around the world. The pathophysiology of fatigue is complex and not fully clear.
Chuanhong Luo   +8 more
doaj   +1 more source

In vivo administration of gut bacterial consortia replicates urolithin metabotypes A and B in a non-urolithin-producing rat model

open access: yesFood & Function, 2023
The two bacterial consortia colonized the intestine of rats and converted UM-0 (non-urolithin-producing) animals into urolithin-producing animals mimicking the UM-A and UM-B metabotypes.
Iglesias Aguirre, Carlos Eduardo   +7 more
openaire   +3 more sources

Tissue deconjugation of urolithin A glucuronide to free urolithin A in systemic inflammation

open access: yesFood & Function, 2019
Urolithin A glucuronide is deconjugated to free urolithin A in systemic inflammation.
Ávila-Gálvez, María Ángeles   +3 more
openaire   +5 more sources

Pomegranate derivative urolithin A enhances vitamin D receptor signaling to amplify serotonin-related gene induction by 1,25-dihydroxyvitamin D

open access: yesBiochemistry and Biophysics Reports, 2020
Mediated by the nuclear vitamin D receptor (VDR), the hormonally active vitamin D metabolite, 1,25-dihydroxyvitamin D3 (1,25D), is known to regulate expression of genes impacting calcium and phosphorus metabolism, the immune system, and behavior ...
Sarah Livingston   +9 more
doaj   +1 more source

Urolithins: The Colon Microbiota Metabolites as Endocrine Modulators: Prospects and Perspectives

open access: yesFrontiers in Nutrition, 2022
Selective estrogen receptor modulators (SERMs) have been used in hormone related disorders, and their role in clinical medicine is evolving. Tamoxifen and raloxifen are the most commonly used synthetic SERMs, and their long-term use are known to create ...
Ravindran Vini   +8 more
doaj   +1 more source

Urolithin A, C, and D, but not iso‐urolithin A and urolithin B, attenuate triglyceride accumulation in human cultures of adipocytes and hepatocytes

open access: yesMolecular Nutrition & Food Research, 2016
ScopeUrolithins (Uro) are ellagic acid (EA)‐derived metabolites produced by gut microbes. There is a growing interest in the biological activities of Uro. Our aim was to evaluate the impacts of Uro on regulating triglyceride (TG) accumulation using cultures of primary human adipocytes and hepatoma Huh7 cells.Methods and resultsUroA, UroB, UroC, UroD ...
Kang, Inhae   +4 more
openaire   +3 more sources

The Compound Specific Antibacterial Activities of Major Urolithins and Their Methyl Ethers

open access: yesJournal of the Turkish Chemical Society, Section A: Chemistry, 2021
The investigation of biological activities of natural products, particularly considering the secondary metabolites, continuously receives attention.
Hayrettin Ozan GÜLCAN   +4 more
doaj   +1 more source

Urolithins: A Prospective Alternative against Brain Aging

open access: yesNutrients, 2023
The impact of host–microbiome interactions on cognitive health and disease has received increasing attention. Microbial-derived metabolites produced in the gut are one of crucial mechanisms of the gut–brain axis interaction, showing attractive perspectives. Urolithins (Uros) are gut microbial-derived metabolites of ellagitannins and ellagic acid, whose
An, Lei   +3 more
openaire   +2 more sources

Effects on Nitric Oxide Production of Urolithins, Gut-Derived Ellagitannin Metabolites, in Human Aortic Endothelial Cells

open access: yesMolecules, 2016
The consumption of foodstuffs yielding circulating compounds able to maintain endothelial function by improving nitric oxide (NO) bioavailability can be considered as an effective strategy for cardiovascular disease prevention.
Valentina Spigoni   +7 more
doaj   +1 more source

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