Results 191 to 200 of about 3,771 (207)

Neuroprotective Attributes of Gut-derived Urolithins in Parkinson’s Disease

Molecular Neurobiology
Urolithins, a class of gut microbiota-derived metabolites, are produced from dietary ellagitannins and ellagic acid. Their pleiotropic activities, including antioxidant, anti-inflammatory, and mitophagy-enhancing effects, position them as promising candidates for Parkinson's disease (PD), a disorder increasingly understood through the lens of gut-brain
Chhetry, Sushila, Roy, Abhideep, Roy, Rubina, Bhattacharya, Pallab, Tapias, Victor, Borah, Anupom   +5 more
openaire   +2 more sources

Neuroprotective effects of urolithin a in a mouse model of intracerebral hemorrhage

Neuropharmacology
Intracerebral hemorrhage (ICH) accounts for 10-15 % of all stroke cases and is associated with high mortality and morbidity. Brain injury caused by ICH includes primary and secondary brain injury. Neuroinflammation and apoptosis play important roles in the pathological process of secondary brain injury after ICH.
Yan Guo, Xiangyu Zhang, Jianzhong Deng, Qiuyang Su, Yuanyuan Liu, Gaili Yan, Sara Xue, V. Wee Yong, Mengzhou Xue   +8 more
openaire   +2 more sources

NMR Spectroscopic Identification of Urolithin G, a Novel Trihydroxy Urolithin Produced by Human Intestinal Enterocloster Species

Journal of Agricultural and Food Chemistry, 2023
Rocio García-Villalba, Juan CARLOS Espin, Maria V Selma   +2 more
exaly  

Gut Bacteria Involved in Ellagic Acid Metabolism To Yield Human Urolithin Metabotypes Revealed

Journal of Agricultural and Food Chemistry, 2023
CARLOS E Iglesias-Aguirre, Rocio García-Villalba, Juan CARLOS Espin   +2 more
exaly  

Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults

Cell Reports Medicine, 2022
Anurag Singh, Davide D’Amico, Penelope A Andreux   +2 more
exaly  

Mechanism of interaction between urolithin A and α-glucosidase: Analysis by inhibition kinetics, fluorescence spectroscopy, isothermal titration calorimetry and molecular docking

Journal of Molecular Structure, 2023
Shiwei Sun, Zhizhou Li
exaly  

Evaluation of electron-transferring cofactor mediating enzyme systems involved in urolithin dehydroxylation in Gordonibacter urolithinfaciens DSM 27213

Journal of Bioscience and Bioengineering, 2020
Shigenobu Kishino, Jun Ogawa
exaly  

A Novel Streptococcus thermophilus FUA329 Isolated from Human Breast Milk Capable of Producing Urolithin A from Ellagic Acid

Foods, 2022
Xiaoyue Hou, Yang Hai, Yaowei Fang
exaly  

Urolithin B, a gut microbiota metabolite, protects against myocardial ischemia/reperfusion injury via p62/Keap1/Nrf2 signaling pathway

Pharmacological Research, 2020
Zumei Liu, You Zhou, Ning Hou
exaly  

Urolithin A prevents streptozotocin-induced diabetic cardiomyopathy in rats by activating SIRT1

Saudi Journal of Biological Sciences, 2022
Gadah Albasher, Saad Alkahtani, Laila Naif Al-Harbi   +2 more
exaly