Results 51 to 60 of about 4,311 (206)
Urolithin A Muscle Endurance in Adults
Researka accepted publication: 1747c75e-7396-47ed-9685-4f97bbb58d86 Source submission: c8408e19-7c24-4e8f-abc2-564ceda228c1 Across these trials, urolithin A improved multiple performance outcomes in middle-aged adults; in older adults, primary walk and
Dominic Lynch
core +6 more sources
Frontiers in Nutrition, 2022 Urolithin A (UA) has received considerable research attention because of its health benefits. However, only a few strains have been reported to produce UA from ellagic acid (EA), and the molecular mechanisms underlying the gut microbiota-mediated ...
Xiaomeng Zhang +20 more
doaj +1 more source
Antioxidants, 2022 (1) Background: To explore the association between microbial phenolic metabolites (MPM) and metabolic syndrome (MetS) and its clinical features in adolescents aged 12.02 ± 0.41 years. (2) Methods: a cross-sectional study was conducted in 560 participants
Emily P. Laveriano-Santos +16 more
doaj +1 more source
Advanced Science, EarlyView.This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun +7 more
wiley +1 more source
Elucidating the Anti-Inflammatory and Anti-Diabetic Properties of Urolithin Bioactive Metabolites from Pecan [PDF]
, 2023 . Pecans are a rich source of ellagitannins which are not absorbed by humans, rather they are catabolized into urolithins by human gut microbiota and enterohepatic circulation.
Bhargava, Prerna
core +1 more source
Mitophagy Activation by Urolithin A to Target Muscle Aging
Calcified Tissue International, 2023 AbstractThe age-related loss of skeletal muscle function starts from midlife and if left unaddressed can lead to an impaired quality of life. A growing body of evidence indicates that mitochondrial dysfunction is causally involved with muscle aging. Muscles are tissues with high metabolic requirements, and contain rich mitochondria supply to support ...
Julie Faitg +3 more
openaire +3 more sources
npj Biofilms and MicrobiomesUrolithins are a class of bioactive metabolites derived from the metabolism of dietary ellagitannins by the human gut microbiota. In the gut, urolithins are dehydroxylated regioselectively based on microbiota composition and activity.
Reilly Pidgeon +3 more
doaj +1 more source
Exploration of Novel Urolithin C Derivatives as Non-Competitive Inhibitors of Liver Pyruvate Kinase
Pharmaceuticals, 2023 The inhibition of liver pyruvate kinase could be beneficial to halt or reverse non-alcoholic fatty liver disease (NAFLD), a progressive accumulation of fat in the liver that can lead eventually to cirrhosis.
Umberto Maria Battisti +12 more
doaj +1 more source
Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality
BMEMat, EarlyView.Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim +9 more
wiley +1 more source
Urolithin A alleviates neuropathic pain and activates mitophagy
Molecular Pain, 2023 Neuropathic pain (NP) occurs frequently in the general population and has a negative impact on the quality of life. There is no effective therapy available yet owing to the complex pathophysiology of NP. In our previous study, we found that urolithin A (UA), a naturally occurring microflora-derived metabolite, could relieve NP in mice by inhibiting the
Chenyi Wang +6 more
openaire +2 more sources