Results 91 to 100 of about 5,657 (242)

Mechanistic Insights Into the Association Between Gut Microbiota Diversity and Atherosclerosis, Acute Coronary Syndrome, and Peripheral Arterial Disease Progression

Clinical Cardiology, Volume 49, Issue 9, September 2026.
Proposed gut‐vascular framework linking microbial ecology to atherosclerotic disease. Diet and related exposures shape dysbiosis or microbial resilience; resulting changes in SCFAs, TMAO, bile acids, and LPS may modulate endothelial function, immune activation, and platelet activity, contributing to atherosclerosis, ACS, and PAD.
Amr Ali Mohamed Abdelgawwad El‐Sehrawy, Usamah Sayed, Zarina Nasirova, Quvonch Tursunov, Omer Qutaiba B. Allela, Lara Asim Kzar, Rajashree Panigrahi, Neeraj Bainsal   +7 more
wiley   +1 more source

Identification of Novel Urolithin Metabolites in Human Feces and Urine after the Intake of a Pomegranate Extract

, 2019
Urolithins are bioactive gut microbiota metabolites of ellagic acid. Here, we have identified four unknown urolithins in human feces after the intake of a pomegranate extract. The new metabolites occurred only in 19% of the subjects.
Rocío García-Villalba (2099278), Juan C. Espín (1961374), Francisco A. Tomás-Barberán (2099284), María V. Selma (2256445)   +3 more
core   +1 more source

Oxidant‐ and Base‐Free Oxidative Lactonization of 2‐Arylbenzoic Acids in Two‐Molecule Photoredox System

ChemPhotoChem, Volume 10, Issue 9, September 2026.
Oxidant‐ and base‐free photoinduced oxidative lactonization of 2‐arylbenzoic acids in a two‐molecule photoredox system under an Ar atmosphere successfully provided the corresponding benzo‐3,4‐coumarins through oxidation by the protonated radical anion of 9,10‐dicyanoanthracene.
Sho Shimamura, Ryoga Hashimoto, Toshiki Furutani, Mugen Yamawaki, Hirotsugu Suzuki, Yasuharu Yoshimi   +5 more
wiley   +1 more source

Mitochondria as the Hub of Apoptosis: A Comprehensive Insight From Mitochondria to Interactions With Other Organelles

MedComm, Volume 7, Issue 9, September 2026.
Mitochondria is the hub of apoptosis in various diseases. The disruption of mitochondrial structure (including membrane rupture, cristae remodeling, and mitochondrial membrane lipid redistribution), the imbalance of mitochondrial dynamics (including fusion and fission, autophagy), the release, disruption, and mutation of mitochondria DNA, as well as ...
Rubin Tan, Jinming Zhao, Rong Wang, Yue Shi, Zaozao Chen, Yixuan Ma, Na Li, Wenqing Duan, Duo Lin, Chunxiang Zhang   +9 more
wiley   +1 more source

Emerging evidence of Urolithin A in sports nutrition: bridging preclinical findings to athletic applications

Frontiers in Nutrition
Urolithin A (UA), a gut microbiota-derived metabolite of ellagic acid and ellagitannins, is emerging as a novel sports nutrition supplement with multifaceted benefits.
Manda Wang, Liang Yu
semanticscholar   +1 more source

Cell Death in Neurodegenerative Diseases: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 9, September 2026.
Regulated cell death pathways, including apoptosis, necroptosis, pyroptosis, ferroptosis, and autophagy‐dependent cell death, interact with mitochondrial dysfunction, proteostasis failure, lysosomal stress, glial remodeling, and neuroinflammation across major neurodegenerative diseases.
Tianjiao Li, Qian Zhang, Yichen Wu, Ruixue Huang   +3 more
wiley   +1 more source

Urolithin A‑producing Limosilactobacillus fermentum FUA033 fermentation significantly improves the sensory and antioxidant properties of strawberry juice

Food Chemistry: X
Probiotics, especially lactic acid bacteria-mediated fermentation, are recognized as an efficient approach to enhance the nutritional and functional properties of food matrices.
Qing Wu, Wenyue Ma, Shu Liu, Fan-Di Zhou, Hao Wu, Xiangyuan Wang, Guang Yang, Yao-Wei Fang   +7 more
semanticscholar   +1 more source

Metabolic Syndrome: From Mechanisms to Therapeutic Interventions

MedComm, Volume 7, Issue 9, September 2026.
A comprehensive overview of molecular mechanisms delves into the potential disease mechanisms of metabolic syndrome, including complex mechanisms such as insulin resistance, chronic low‐grade inflammation, oxidative stress, and epigenetic modifications, and how these mechanisms contribute to the development of metabolic syndrome. Here, the relationship
Mengyao Yan, Qian Xiang
wiley   +1 more source

Evaluating the Impact of Urolithin A Supplementation on Running Performance, Recovery, and Mitochondrial Biomarkers in Highly Trained Male Distance Runners

Sports Medicine
Urolithin A (UA) is a metabolite produced by gut bacteria following the consumption of ellagitannin-rich foods. Clinical trials in middle-aged and older adults demonstrated that supplementation with UA improves muscle strength, endurance, and biomarkers ...
Jamie Whitfield, A. K. McKay, Nicolin Tee, Rachel McCormick, Aimee Morabito, Leonidas G. Karagounis, A. Fouassier, Davide D’Amico, Anurag Singh, L. Burke, J. A. Hawley   +10 more
semanticscholar   +1 more source

Urolithin A has antiplatelet effects in contrast to its glucuronide, urolithin B, and isourolithin A

Frontiers in Cardiovascular Medicine
IntroductionConsumption of dietary ellagitannins has been suggested to have protective effects against cardiovascular disease, likely due to the colonic formation of urolithins and their subsequent systemic absorption.
Alina Soloviova, Alina Soloviova, Marcel Hrubša, Carlos J. García, Zuzana Lomozová, Francisco A. Tomás-Barberán, Přemysl Mladěnka   +6 more
doaj   +1 more source