Results 101 to 110 of about 372 (136)

Research progress of ellagitannin intestinal metabolite urolithins

China Journal of Chinese Materia Medica, 2016
Ellagitannins is a kind of phenolic compounds with many biological activities. Recent studies have found that the effective ingredients of these compounds have close relationship with their colon-derived bacteria metabolites, that is urolithins.
Ben-Hong, Zhou, Zhen-Peng, Qiu, Hui-Lan, Yi, Ding-Shan, Zhou, Jing, Wang, Yue, Wu   +5 more
openaire   +2 more sources

Synthesis of urolithin derivatives and their anti-inflammatory activity

Biochemical and Biophysical Research Communications
Two series of urolithin derivatives, totally 38 compounds, were synthesized. Their anti-inflammatory activity was investigated by detecting the inhibitory effects on the expression of TNF-α in bone marrow-derived macrophages (BMDMs), showing that 24 of 38 ones reduced the expression of TNF-α.
Xintong Li, Zhengzheng Zhang, Guangsen Xu, Zhiying Li, Chunhua Lu, Yuemao Shen   +5 more
openaire   +2 more sources

Impact of the Natural Compound Urolithin A on Health, Disease, and Aging

Trends in Molecular Medicine, 2021
Penelope Andreux, , Johan Auwerx
exaly  

NMR Spectroscopic Identification of Urolithin G, a Novel Trihydroxy Urolithin Produced by Human Intestinal Enterocloster Species

Journal of Agricultural and Food Chemistry, 2023
David Beltran Riquelme, Tomás-Barberán F A, Juan CARLOS Espin   +2 more
exaly  

Urolithin A Produced by Novel Microbial Fermentation Possesses Anti-aging Effects by Improving Mitophagy and Reducing Reactive Oxygen Species in Caenorhabditis elegans

Journal of Agricultural and Food Chemistry, 2023
Shumao Cui, Qiuxiang Zhang
exaly  

Ellagic acid and intestinal microflora metabolite urolithin A: A review on its sources, metabolic distribution, health benefits, and biotransformation

Critical Reviews in Food Science and Nutrition, 2023
Xin Tang, Bingyong Mao, Jianxin Zhao
exaly  

Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults

Cell Reports Medicine, 2022
Penelope Andreux, , Johan Auwerx
exaly  

Mechanism of interaction between urolithin A and α-glucosidase: Analysis by inhibition kinetics, fluorescence spectroscopy, isothermal titration calorimetry and molecular docking

Journal of Molecular Structure, 2023
, Shiwei Sun
exaly  

Pharmacological Effects of Urolithin A and Its Role in Muscle Health and Performance: Current Knowledge and Prospects

Nutrients, 2023
He Qian, Chang Liu, Haotian Zhao
exaly  

Targeting aging with urolithin A in humans

Ageing Research Reviews
Urolithin A (UA) is a gut metabolite derived from ellagic acid. This systematic review assesses the potential geroprotective effect of UA in humans. In five studies including 250 healthy individuals, UA (10–1000 mg/day) for a duration ranging from 28 days to 4 months, showed a dose-dependent anti-inflammatory effect and upregulated some mitochondrial ...
Kuerec, Ajla Hodzic, Lim, Xuan K., Khoo, Anderson LY, Sandalova, Elena, Guan, Lihuan, Feng, Lei, Maier, Andrea B.   +6 more
openaire   +1 more source