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Synthesis of urolithin A 3- and 8-glucuronides via intramolecular biaryl coupling
Results in ChemistryUrolithins, 6H-dibenzo[b,d]pyran-6-one derivatives, are metabolites produced by gut microbiota from ellagic acid, a natural antioxidant. They are more efficiently absorbed than ellagic acid and contribute to the health benefits of ellagitannin-rich foods.
Takanori Nagai +5 more
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Applied SciencesOil extracted from walnuts leaves behind large amounts of defatted press cake that still retains valuable nutrients. Solid state fermentation (SSF) is a promising method to liberate bioactive compounds from food by-products.
Wolfram Manuel Brück +2 more
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AntioxidantsObesity is in epidemic proportions in many parts of the world, contributing to increasing rates of non-alcoholic fatty liver disease (NAFLD). NAFLD represents a range of conditions from the initial stage of fatty liver to non-alcoholic steatohepatitis ...
Tharani Senavirathna +3 more
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Shipin gongye ke-jiThe rambutan peel was rich in polyphenols, in order to further investigate the technology of rambutan peel polyphenol production and its product development, this study prepared rambutan peel polyphenol water extract (RPE) by high pressure steaming ...
Jiao LI +6 more
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The Therapeutic Potential of Urolithin A for Cancer Treatment and Prevention
Current Cancer Drug Targets, 2022Background: Urolithin A is the metabolite of natural polyphenol ellagic acid and ellagitannins generated by gut microbiota. Urolithin A is better absorbed in the gastrointestinal tract than its parent substances. Thus, the variable effects of ellagitannin-reach food (like pomegranate fruit, walnuts, tea, and others) on people's health might be linked ...
exaly +3 more sources
The Synthesis of Urolithins and their Derivatives and the Modes of Antitumor Action
Mini-Reviews in Medicinal Chemistry, 2023Abstract: Urolithins are microbial metabolites derived from berries and pomegranate fruits, which display anti-inflammatory, anti-oxidative, and anti-aging activities. There are eight natural urolithins (urolithin A-E, M5, M6 and M7), which have been isolated by now.
Lei Yao, Xiangrong Xu, Zhuanhong Liu
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Gastrointestinal stability of urolithins: an in vitro approach
European Journal of Nutrition, 2015Urolithins are bioactive ellagitannin-derived metabolites showing a wide phenotypic variation in their production by the gut microbiota. This work represents a first in vitro step toward the development of new strategies focused on the oral supplementation of urolithins with the aim of overcoming their selective production and making their putative ...
MENA PARRENO, Pedro Miguel +4 more
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Journal of Agricultural and Food Chemistry, 2017
Antimelanogenic agents from natural sources have been widely investigated. Urolithin A (UA) and B (UB), the main gut microflora metabolites of dietary ellagic acid derivatives, have various bioactivities such as anti-inflammatory and antiaging effects.
Shang-Ta Wang +3 more
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Antimelanogenic agents from natural sources have been widely investigated. Urolithin A (UA) and B (UB), the main gut microflora metabolites of dietary ellagic acid derivatives, have various bioactivities such as anti-inflammatory and antiaging effects.
Shang-Ta Wang +3 more
openaire +2 more sources