Results 21 to 30 of about 372 (136)

Isolation of Human Intestinal Bacteria Capable of Producing the Bioactive Metabolite Isourolithin A from Ellagic Acid

open access: yesFrontiers in Microbiology, 2017
Urolithins are intestinal microbial metabolites produced from ellagitannin- and ellagic acid-containing foods such as walnuts, strawberries, and pomegranates.
María V. Selma   +7 more
doaj   +1 more source

Constituents and Metabolites of a French Oak Wood Extract (Robuvit®) in Serum and Blood Cell Samples of Women Undergoing Hysterectomy

open access: yesFrontiers in Pharmacology, 2020
Ellagitannins are signature constituents of oak wood and their consumption has been associated with various health benefits. In vivo, they undergo metabolic degradation including gut microbial metabolism yielding urolithins.
Linda Volpp   +5 more
doaj   +1 more source

Interactions between Gut Microbiota and Polyphenols: New Insights into the Treatment of Fatigue

open access: yesMolecules, 2022
Fatigue seriously affects people’s work efficiency and quality of life and has become a common health problem in modern societies around the world. The pathophysiology of fatigue is complex and not fully clear.
Chuanhong Luo   +8 more
doaj   +1 more source

Tissue deconjugation of urolithin A glucuronide to free urolithin A in systemic inflammation

open access: yesFood & Function, 2019
Urolithin A glucuronide is deconjugated to free urolithin A in systemic inflammation.
Ávila-Gálvez, María Ángeles   +3 more
openaire   +5 more sources

Urolithins: The Colon Microbiota Metabolites as Endocrine Modulators: Prospects and Perspectives

open access: yesFrontiers in Nutrition, 2022
Selective estrogen receptor modulators (SERMs) have been used in hormone related disorders, and their role in clinical medicine is evolving. Tamoxifen and raloxifen are the most commonly used synthetic SERMs, and their long-term use are known to create ...
Ravindran Vini   +8 more
doaj   +1 more source

Urolithin A, C, and D, but not iso‐urolithin A and urolithin B, attenuate triglyceride accumulation in human cultures of adipocytes and hepatocytes

open access: yesMolecular Nutrition & Food Research, 2016
ScopeUrolithins (Uro) are ellagic acid (EA)‐derived metabolites produced by gut microbes. There is a growing interest in the biological activities of Uro. Our aim was to evaluate the impacts of Uro on regulating triglyceride (TG) accumulation using cultures of primary human adipocytes and hepatoma Huh7 cells.Methods and resultsUroA, UroB, UroC, UroD ...
Kang, Inhae   +4 more
openaire   +3 more sources

NMR Spectroscopic Identification of Urolithin G, a Novel Trihydroxy Urolithin Produced by Human Intestinal Enterocloster Species

open access: yesJournal of Agricultural and Food Chemistry, 2023
Urolithins are gut microbiota metabolites of ellagic acid. Here, we have identified and chemically characterized a novel urolithin produced from urolithin D (3,4,8,9-tetrahydroxy urolithin) by in vitro incubation with different human gut Enterocloster species under anaerobic conditions. Urolithin G (3,4,8-trihydroxy urolithin) was identified by 1H NMR,
David Beltrán   +7 more
openaire   +3 more sources

The Compound Specific Antibacterial Activities of Major Urolithins and Their Methyl Ethers

open access: yesJournal of the Turkish Chemical Society, Section A: Chemistry, 2021
The investigation of biological activities of natural products, particularly considering the secondary metabolites, continuously receives attention.
Hayrettin Ozan GÜLCAN   +4 more
doaj   +1 more source

HIV-1 Integrase Inhibitory Effects of Major Compounds Present in CareVid™: An Anti-HIV Multi-Herbal Remedy

open access: yesLife, 2022
In our continued study on the anti-HIV activity of compounds present in CareVidTM, we report the HIV-1 integrase ((HIV-1 IN) inhibitory effects of pellitorine (1), oleuropein (2), magnoflorine (3), crotepoxide (4), ent-kaurane-16β,17-diol (5 ...
Winnie Rotich   +5 more
doaj   +1 more source

Effects on Nitric Oxide Production of Urolithins, Gut-Derived Ellagitannin Metabolites, in Human Aortic Endothelial Cells

open access: yesMolecules, 2016
The consumption of foodstuffs yielding circulating compounds able to maintain endothelial function by improving nitric oxide (NO) bioavailability can be considered as an effective strategy for cardiovascular disease prevention.
Valentina Spigoni   +7 more
doaj   +1 more source

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