Results 171 to 180 of about 3,771 (207)
Eicosapentaenoic Acid and Urolithin a Synergistically Mitigate Heat Stroke-Induced NLRP3 Inflammasome Activation in Microglial Cells. [PDF]
NutrientsCho H, Kim J, Park Y, Kim YC, Chung S.
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International Journal of Molecular Sciences, 2021 Leukemia is persistently a significant cause of illness and mortality worldwide. Urolithins, metabolites of ellagic acid and ellagitannins produced by gut microbiota, showed better bioactive compounds liable for the health benefits exerted by ellagic ...
Abdulaziz Musa Alzahrani +2 more
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Nutrients, 2023 Urolithin A (UA) is a naturally occurring compound derived from the metabolism of gut microbiota, which has attracted considerable research attention due to its pharmacological effects and potential implications in muscle health and performance.
He Qian, Chang Liu, Song Ge
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Journal of Agricultural and Food Chemistry, 2023 Urolithin, intestinal microbiota metabolites of ellagitannin-rich foods, exhibit anti-aging activities. However, urolithin A is significantly superior to other types of urolithin with regard to this anti-aging function.
Shumao Cui +2 more
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The Therapeutic Potential of Urolithin A for Cancer Treatment and Prevention
Current Cancer Drug Targets, 2022Background: Urolithin A is the metabolite of natural polyphenol ellagic acid and ellagitannins generated by gut microbiota. Urolithin A is better absorbed in the gastrointestinal tract than its parent substances. Thus, the variable effects of ellagitannin-reach food (like pomegranate fruit, walnuts, tea, and others) on people's health might be linked ...
Vladimir Rogovskii
exaly +3 more sources
Anti-inflammatory and antioxidant mechanisms of urolithin B in activated microglia
Phytomedicine, 2019 Background: Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical fruits, and medicinal herbs.
Jin-Sun Park, Hee-Sun Kim
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Impact of the Natural Compound Urolithin A on Health, Disease, and Aging [PDF]
Trends in Molecular Medicine, 2021 Urolithin A (UA) is a natural compound produced by gut bacteria from ingested ellagitannins (ETs) and ellagic acid (EA), complex polyphenols abundant in foods such as pomegranate, berries, and nuts. UA was discovered 40 years ago, but only recently has its impact on aging and disease been explored.
Davide D’Amico +2 more
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The Synthesis of Urolithins and their Derivatives and the Modes of Antitumor Action
Mini-Reviews in Medicinal Chemistry, 2023Abstract: Urolithins are microbial metabolites derived from berries and pomegranate fruits, which display anti-inflammatory, anti-oxidative, and anti-aging activities. There are eight natural urolithins (urolithin A-E, M5, M6 and M7), which have been isolated by now.
Lei Yao, Xiangrong Xu, Zhuanhong Liu
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