Results 91 to 100 of about 360,869 (356)

NRF2 Deficiency in Bladder Epithelial Cells Owing to Ubiquitination by N6-Methyladenosine-Modified TRIM21 Induces Oxidative Stress and Inflammation to Aggravate IC/BPS

open access: yesJournal of Inflammation Research
Zongyao Fan,1,* Qingyu Ge,2,* Bin Ni,1,* Junjie Zhang,1 Tianpeng Du,1 Hewei Xu,3 Zheng Duan,1 Sicong Zhang,1 Chao Wang,4 Jun Xue,1 Feng Ling,5 Zhengsen Chen,1 Baixin Shen,1 Zhongqing Wei1 1Department of Urology, The Second ...
Fan Z   +13 more
doaj  

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

open access: yesAdvanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang   +7 more
wiley   +1 more source

Bladder Leiomyoma Presenting with Recurrent Cystitis: A Case Report

open access: yesResearch and Reports in Urology
Kazuhiro Fukuda,1 Satoru Kotoda,1 Kaori Fukaya,1 Eisuke Yokota,1 Shigetaka Yamasaki,2 Shigeo Horie3,4 1Department of Urology, Koshigaya Municipal Hospital, Koshigaya, Saitama, Japan; 2Department of Pathology, Tokyo Rinkai Hospital, Tokyo, Japan ...
Fukuda K   +5 more
doaj  

European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2020 Update.

open access: yesEuropean Urology, 2020
M. Rouprêt   +19 more
semanticscholar   +1 more source

A Sirtuin‐1‐Targeted Gene‐Activating Tetrahedral DNA Attenuates Bladder Fibrosis by Restoring Mitophagy in Fibroblasts via the SIRT1‐FOXO3‐BNIP3 Axis

open access: yesAdvanced Science, EarlyView.
The SIRT1‐targeted saRNA‐delivering tetrahedral DNA (TSA) treatment effectively upregulates SIRT1 expression, which subsequently promotes FOXO3A deacetylation. This deacetylation event relieves FOXO3A's transcriptional repression on the BNIP3 gene, thereby initiating PINK1‐PARKIN‐dependent mitophagy.
Wei Wang   +10 more
wiley   +1 more source

Early PIVKA-II Response Associated with Treatment Efficacy and Survival Outcomes for Patients with Advanced Hepatocellular Carcinoma Receiving Immune Checkpoint Inhibitors and Targeted Therapy

open access: yesJournal of Hepatocellular Carcinoma
Zheng-Kang Fang,1,2 Yu-Ting Xiao,1 Xia Feng,1 Zhe-Jin Shi,1,3 Si-Yu Liu,4 Yang Yu,5 Li-Ming Jin,1 Dong-Sheng Huang,1 Cheng-Wu Zhang,1 Jun-Wei Liu,1 Lei Liang1 1Department of General Surgery, Cancer Center, Hepatobiliary & Pancreatic Surgery and ...
Fang ZK   +10 more
doaj  

Disrupting Lipid Raft Microdomains to Block Polyploid Giant Cancer Cell Budding and Enhance Radiotherapy Response

open access: yesAdvanced Science, EarlyView.
Radiation induces polyploid giant cancer cells (PGCCs) that regenerate tumors through virus‐like budding. This process depends on a SNCG–FLOT2–CHMP4B signaling axis functioning in lipid raft microdomains. Disrupting these domains using statins or anti‐PCSK9 antibodies blocks PGCC budding, suppresses tumor repopulation, and enhances radiotherapy ...
Zheng Deng   +20 more
wiley   +1 more source

Investigating Causal Links Between Uterine Prolapse, Urinary Tract Infections, and Lower Urinary Tract Symptoms: A Two-Sample Mendelian Randomization Study

open access: yesInternational Journal of Women's Health
Xiaoyue Zhu, Chunyan Hu, Anneng Hu, Yongbo Zheng, Junyang Li, Fuwen Luo, Lin Yang, Yuhang Lin, Xiaodong Yu Department of Urology, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, People’s Republic of ChinaCorrespondence: Xiaodong ...
Zhu X   +8 more
doaj  

Uroplakins and their potential applications in urology

open access: green, 2016
M Matuszewski   +5 more
openalex   +1 more source

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