Results 81 to 90 of about 489,677 (387)

Epigenetic Activation of CCDC183‐AS1 Promotes Osteoclastogenesis and Prostate Cancer Bone Metastasis Through the FUBP1/LIGHT Axis

open access: yesAdvanced Science, EarlyView.
CCDC183‐AS1 overexpression enhanced the ability of PCa cells to spread to the bone by inducing osteoclastogenesis. Mechanistically, CCDC183‐AS1 interacted with FUBP1 and enhanced its stability, which promoted the transcription of TNFSF14 (LIGHT). Copy number gain‐induced KDM5C epigenetically upregulated CCDC183‐AS1 expression by recruiting TET1 to the ...
Chuandong Lang   +10 more
wiley   +1 more source

Long-term complications of continent catheterizable channels: a problem for transitional urologists. [PDF]

open access: yes, 2018
A majority of the transitional urology patient population have neurogenic bladder and many of these patients have undergone creation of continent catheterizable channels (CCCs) to facilitate bladder emptying.
Baradaran, Nima   +2 more
core  

Slowdown of urology residents’ learning curve during the COVID‐19 emergency

open access: yesBJU International, 2020
The coronavirus disease 2019 (COVID-19), has rapidly been spreading worldwide and Italy has been hit hard, forced the Italian Healthcare System to change and adapt to these extreme conditions.
F. Porpiglia   +11 more
semanticscholar   +1 more source

Hypoglycemia Induces Diabetic Macrovascular Endothelial Dysfunction via Endothelial Cell PANoptosis, Macrophage Polarization, and VSMC Fibrosis

open access: yesAdvanced Science, EarlyView.
This study investigates hypoglycemia‐induced diabetic macrovascular endothelial dysfunction. It reveals that hypoglycemia triggers ZBP1‐dependent PANoptosis of endothelial cells, proinflammatory polarization of macrophages, and fibrosis of vascular smooth muscle cells (VSMCs) in diabetic mice.
Deyu Zuo   +10 more
wiley   +1 more source

Genomic biomarkers in prostate cancer. [PDF]

open access: yes, 2018
Prostate cancer is the most common non-cutaneous cancer among men in the United States. In the last decade there has been a rapid expansion in the field of biomarker assays for diagnosis, prognosis, and treatment prediction in prostate cancer.
Cooperberg, Matthew R   +3 more
core  

European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2023 Update.

open access: yesEuropean Urology, 2023
M. Rouprêt   +19 more
semanticscholar   +1 more source

Disruption of ARID1B Recruitment to the Nuclear Pore Complex as a New Anticancer Therapeutic Strategy

open access: yesAdvanced Science, EarlyView.
This study identifies ARID1B as a chromatin‐bound driver of tumor growth in TNBC. ARID1B impairs ARID1A function and directly activates oncogenic programs through SWI/SNF remodeling. Its nuclear localization, mediated by the KPNA2–KPNB1–RANBP2 import machinery, is essential for its tumor‐promoting activity.
Olena Odnokoz   +14 more
wiley   +1 more source

Lower Urinary Tract Symptoms in Men Living with Human Immunodeficiency Virus: A Case-control Study

open access: yesJournal of Urological Surgery
Objective: Human immunodeficiency virus (HIV)/acquired immune deficiency syndrome constitutes a global pandemic affecting populations worldwide. There’s a gap in data regarding lower urinary tract symptoms (LUTS) among men living with HIV (MLWH) during ...
Ersin Köseoğlu   +5 more
doaj   +1 more source

Neuromodulation in neurogenic bladder. [PDF]

open access: yes, 2016
While neuromodulation is a well-established treatment option for patients with non-neurogenic overactive bladder and urinary retention, its applicability to the neurogenic bladder population has only recently been examined more in depth.
Sanford, Melissa T, Suskind, Anne M
core   +1 more source

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