Results 81 to 90 of about 360,869 (356)

Secondary Analysis of PSA and BCR-Free Survival in Asian Prostate Cancer Patients

Cancer Management and Research
Xin Gao,1,* Yijun Fu,1,* Zimei Mo,1 Yongtong Ruan2 1Department of Urology, Yangjiang Hospital of Traditional Chinese Medicine, Affiliated to Guangzhou University of Chinese Medicine, Yangjiang, Guangdong, People’s Republic of China ...
Gao X, Fu Y, Mo Z, Ruan Y
doaj  

European Association of Urology-American Society of Clinical Oncology Collaborative Guideline on Penile Cancer: 2023 Update.

European Urology, 2023
O. Brouwer, M. Albersen, A. Parnham, C. Protzel, C. Pettaway, B. Ayres, Tiago Antunes-Lopes, L. Barreto, R. Campi, J. Crook, S. Fernandez-Pello, I. Greco, M. S. van der Heijden, P. Johnstone, M. Kailavasan, Kenneth Manzie, Jack David Marcus, A. Necchi, P. Oliveira, J. Osborne, L. Pagliaro, H. García-Perdomo, R. Rumble, A. Sachdeva, V. Sakalis, Łukasz Zapała, Diego F. Sánchez Martínez, Philippe E. Spiess, S. Tagawa   +28 more
semanticscholar   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Association of High Tumor-Stroma Ratio with Prostate Cancer Progression: Insights from Clinical and Genomic Data

International Journal of General Medicine
Wenbo Xu,1,2 Qian Niu,3 Kun Zhao,1,2 Haozhi Zhao,1,2 Long Zhang,1,2 Wenxuan Li,1,2 Hong Yan,3 Zhilong Dong1,2 1Institute of Urology, Gansu Province Clinical Research Center for Urinary System Disease, The Second Hospital & Clinical Medical School ...
Xu W, Niu Q, Zhao K, Zhao H, Zhang L, Li W, Yan H, Dong Z   +7 more
doaj  

Urology residency training during the pandemic. A review of the current literature

, 2022
P.V. Stamatakos, A. Leventi, D. Moschotzopoulos, E. Papadimitriou, T. Paizis, A. Kaoullas, I. Glykas, C. Fragkoulis, G. Papadopoulos, G. Ntoumas   +9 more
openalex   +1 more source

XPC Deficiency Activate Cisplatin‐Mediated Autophagy in Bladder Cancer by Limiting Novel PHRF1‐Mediated Ubiquitination of the p53 Protein

Advanced Science, EarlyView.
This study reveals that XPC regulates autophagy signaling beyond its noncanonical DNA repair role, uncovering the XPC‐p‐ATM‐KDM4A‐PHRF1 axis as a novel mechanism for autophagy modulation under DNA damage stress. It identifies PHRF1 as a novel p53 ubiquitin ligase.
Baixiong Zhao, Yaqin Huang, Jiazhong Shi, Xiaozhou Zhou, Johan Bourghardt Fagman, Liwei Wang, Sha Liu, Wuxing Wang, Yuting Liu, Zhiwen Chen, Jin Yang   +10 more
wiley   +1 more source

IL-6/IL-6R Signaling Blockade Alleviates Chronic Allograft Rejection by Modulating Germinal Center B Cells and Allograft Inflammation in Murine Cardiac Transplantation

Journal of Inflammation Research
Renfei Xia,1,* Xiaoyi Shi,2,* Hengcheng Zhang,3,* Wenli Zeng,1 Zhe Yang,4 Jian Xu,1 Jianning Wang,4 Yun Miao,1 Tao Liao1,4 1Department of Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, People’s ...
Xia R, Shi X, Zhang H, Zeng W, Yang Z, Xu J, Wang J, Miao Y, Liao T   +8 more
doaj  

Fe‐S Protein FDX1 Triggers Tumor‐Intrinsic Innate Immunity via Mitochondrial Nucleic Acids Release to Orchestrate Ferroptosis in CCRCC

Advanced Science, EarlyView.
Restoration of the mitochondrial Fe–S protein FDX1 suppresses clear cell renal cell carcinoma by coupling ferroptosis with tumor‐intrinsic innate immune activation. FDX1 induces mitochondrial dysfunction and mtDNA/mt‐dsRNA release, activating cGAS–STING and RIG‐I/MDA5–MAVS signaling to elicit type I interferon responses, thereby promoting antigen ...
Xing Huang, Shaoqing Yu, Wenjie Wei, Wen Tao, Tianwei Cai, Lequan Wen, Jiali Ye, Chi Zhang, Huayi Feng, Senming Cao, Baojun Wang, Xin Ma, Yan Huang, Xu Zhang   +13 more
wiley   +1 more source

A Pan-Cancer Analysis of Natriuretic Peptide Receptor 3 (NPR3) with Clinical Cohort and in vitro Validation

Journal of Inflammation Research
Yifan Liu,1,* Jiangui Liu,1,* Yuanan Li,1,* Zihui Zhao,1,* Donghao Lyu,1 Keqin Dong,1 Maodong Wei,1 Runzhi Huang,2 Bingnan Lu,1 Xiuwu Pan1 1Department of Urology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University
Liu Y, Liu J, Li Y, Zhao Z, Lyu D, Dong K, Wei M, Huang R, Lu B, Pan X   +9 more
doaj  

Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF‐κB and TGF‐β Signaling Pathways

Advanced Science, EarlyView.
This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye, Jianfeng Xiang, Siqi Zhou, Qintao Ge, Aihetaimujiang Anwaier, Kun Chang, Gang Wei, Jiahe Lu, Xi Tian, Shuxuan Zhu, Yuchen Jiang, Wei Zhang, Tingting Cai, Moran Xu, Dingwei Ye, Danfeng Xu, Tao Wang, Hailiang Zhang, Wenhao Xu   +18 more
wiley   +1 more source