Exploring microorganism–host interactions: Emerging organoid models and analytical approaches
Abstract Microorganisms play a vital role in human health through their interactions with the body. Studies of host–microbe mechanisms and interactions are crucial for advancing health management. Recently, the organoid‐based models have provided new platforms in this field.
Yue Shi +6 more
wiley +1 more source
Adhesion and entry of uropathogenic Escherichia coli
To effectively colonize a host animal and cause disease, many bacterial pathogens have evolved the mechanisms needed to invade and persist within host cells and tissues. Recently it was discovered that uropathogenic Escherichia coli, the primary causative agent of urinary tract infections, can invade and replicate within uroepithelial cells.
openaire +2 more sources
Combinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice [PDF]
Catheter-associated urinary tract infections (CAUTIs) constitute the majority of nosocomial urinary tract infections (UTIs) and pose significant clinical challenges.
Caparon, Michael G +8 more
core +2 more sources
Parameters Influencing the Plasma‐Mediated Inactivation of Microorganisms and Viruses in Wastewater
Wastewater parameters, e.g., chemical oxygen demand (COD), influences the antimicrobial and antiviral efficacy of plasma. ABSTRACT Pathogenic microorganisms and viruses in water pose an environmental risk demanding for effective remediation tools like physical plasma. However, parameters influencing its efficiency are mostly descriptive.
Veronika Hahn +7 more
wiley +1 more source
Molecular Detection of Type 1 Fimbriae-Encoding Gene (fimH) in Uropathogenic Escherichia coli Strains Isolated from Outpatients with Urinary Tract Infection [PDF]
Background & Objective: Urinary Tract Infection (UTI) is one of the most common infections in all age groups. The majority of these infections are caused by Uropathogenic Escherichia coli (UPEC) strains. Colonization, attachment to uroepithelium, and the
Nemat Shams, Amin Jaydari
doaj +2 more sources
mBEDOs: a scalable platform for modeling urothelial aging. mBEDOs derived from aged mouse bladders capture essential molecular and cellular features of urothelial aging and provide a versatile system for high‐throughput metabolic profiling, therapeutic screening via metabolite supplementation, age‐ and sex‐based analyses, infection modeling, and immune–
Adwaita R. Parab +8 more
wiley +1 more source
Immune modulation by group B Streptococcus influences host susceptibility to urinary tract infection by uropathogenic Escherichia coli [PDF]
Urinary tract infection (UTI) is most often caused by uropathogenic Escherichia coli (UPEC). UPEC inoculation into the female urinary tract (UT) can occur through physical activities that expose the UT to an inherently polymicrobial periurethral, vaginal,
Amanda L. Lewis +75 more
core +2 more sources
ABSTRACT Over the years, numerous D‐ and z‐values have been published in the scientific literature. While these values initially appear to be valid criteria for assessing and comparing the heat resistance of different microorganisms under the same conditions or the same microorganism under different conditions, this is not always the case.
Astrid Gędas, Agnes Weiss
wiley +1 more source
The LPS core is critical for virulence in Pectobacterium carotovorum, as its truncation disrupts outer membrane protein assembly, reducing protease secretion, motility, and soft rot symptoms. ABSTRACT Lipopolysaccharide (LPS) is a critical component of the bacterial outer membrane, which serves as a permeability barrier and site for sensing ...
Yejin Park +4 more
wiley +1 more source
Molecular epidemiology of extraintestinal pathogenic (uropathogenic) Escherichia coli
Molecular epidemiological analyses of extraintestinal pathogenic Escherichia coli (ExPEC), which are also called "uropathogenic E. coli" since they are the principle pathogens in urinary tract infection, involve structured observations of E. coli as they occur in the wild.
James R, Johnson, Thomas A, Russo
openaire +2 more sources

