Results 71 to 80 of about 499,047 (213)
Discovery and antibacterial study of potential PPK1 inhibitors against uropathogenic E. coli
Novel antibacterial agents are urgently needed to address the infections caused by multi-drug resistant bacteria. Urinary tract infections are common infectious diseases in clinical.
Liang Peng +9 more
doaj +1 more source
UropathogenicEscherichia coli-Associated Exotoxins [PDF]
ABSTRACTEscherichia coliare a common cause of infectious disease outside of the gastrointestinal tract. Several independently evolvedE. coliclades are common causes of urinary tract and bloodstream infections. There is ample epidemiological andin vitroevidence that several different protein toxins common to many, but not all, of these strains are ...
openaire +2 more sources
Intermittent catheter use can damage the urinary tract and predispose to infection. We deployed a complex human urothelial model to investigate. Catheter contact induced compressive and shear stress causing umbrella cell disruption, reduced barrier function, inflammation and increased cell adhesion to the catheter surface.
Nazila V. Jafari, Jennifer L. Rohn
wiley +1 more source
Analysis of Escherichia coli strains causing bacteriuria during pregnancy: selection for strains that do not express type 1 fimbriae [PDF]
Escherichia coli isolates from patients with bacteriuria of pregnancy were compared by PCR with isolates from patients with community-acquired cystitis for the presence of established virulence determinants.
Graham, J.C. +5 more
core
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi +6 more
wiley +1 more source
Perceiving molecular evolution processes in Escherichia coli by comprehensive metabolite and gene expression profiling [PDF]
Vijayendran C, Barsch A, Friehs K, Niehaus K, Becker A, Flaschel E. Perceiving molecular evolution processes in Escherichia coli by comprehensive metabolite and gene expression profiling. GENOME BIOLOGY.
Flaschel, Erwin +5 more
core +1 more source
ABSTRACT Background and Aims A surge in antimicrobial resistance and multidrug‐resistant organisms among uropathogens have complicated its management over time. It is imperative to examine epidemiology and local antimicrobial susceptibility patterns to promote evidence‐based management.
Sanga Tenzin +7 more
wiley +1 more source
Biofilm and hemagglutinin formation: a Hallmark for drug resistant uropathogenic Escherichia coli
Objective Urinary tract infection (UTI) is one of the most frequent disease encounters in pregnant mothers, and the most drug resistant, biofilm and hemagglutinin producer Uropathogenic Escherichia coli (UPEC) is the major etiologic agent. Therefore, the
Dawit Gebreegziabiher Hagos +3 more
doaj +1 more source
Water, water, every where—the advent of hydrated pili structure
Protein structure is defined by its surrounding water. Naturally, this is also true for the gigantic protein filaments that pathogenic bacteria use to attach to and colonize their host cells. Structures of these filaments for which water can be identified with high confidence have stayed elusive for the longest time.
Hiroya Oki +3 more
wiley +1 more source
Uropathogenic Escherichia coli
Urinary tract infections (UTIs) are among the most common infections encountered worldwide in clinical practice. Escherichia coli is by far the most frequent cause of infections responsible for nearly 80–90% of the infections. The strains of E. coli causing UTI are termed as uropathogenic E. coli.
Navneet Kaur +3 more
openaire +2 more sources

