Results 21 to 30 of about 28,025 (230)
Clinical and Experimental Obstetrics & Gynecology, 2021 The current paper reports a survey on intrahepatic cholestasis of pregnancy (ICP), concerning obstetric outcomes and treatment of the disease. The survey assessed the opinions of contributors on ursodeoxycholic acid (UDCA) therapy and ICP care.
Caroline Ovadia, Ugo Indraccolo
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Does ursodeoxycholic acid change the proliferation of the colorectal mucosa? A randomized, placebo-controlled study [PDF]
, 2003 Background: In animal models ursodeoxycholic acid (UDCA) showed a chemoprotective effect against colon cancer. To explain this, a reduced proliferation of the colorectal mucosal proliferation was suggested.
Diebold, J. +6 more
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Journal of Lipid Research, 1983 The formation of ursodeoxycholic acid from chenodeoxycholic acid and the role of 7-ketolithocholic acid as an intermediate in this biotransformation were studied in vitro in fecal incubations as well as in vivo in the human colon.
H Fromm, R P Sarva, F Bazzoli
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Experimental isovalthinuria. III. Induction by bile acids, and hypocholesterolemic agents [PDF]
, 1963 Some bile acids (dehydrocholic, cholic, chenodeoxycholic, ursodeoxycholic, and deoxycholic acids), and some hypocholesterolemic agents (22, 25 diazacholestanol, 20,25-diazacholesterol, triparanol, and SKF 525-A) are the inducers of isovalthinuria in ...
Ubuka, Toshihiko
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Journal of Lipid Research, 1980 We examined by titration the electrochemical properties, apparent pK (pK'a), precipitation pH, and undissociated bile acid solubilities of chenodeoxycholic acid and its 7 beta epimer, ursodeoxycholic acid and their glycine conjugates as functions of a ...
H Igimi, M C Carey
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A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis. [PDF]
, 2019 Primary biliary cholangitis (PBC) is typically associated with elevated serum bile acid levels and pruritus, but pruritus is often refractory to treatment with existing therapies.
Apostol, George +15 more
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Journal of Lipid Research, 1981 Six strains of lecithinase-lipase-negative Clostridia, isolated from human feces, were capable of oxidizing chenodeoxycholic acid to 3 alpha-hydroxy-7 keto-5 beta-cholanoic acid and of epimerizing it to ursodeoxycholic acid.
R Edenharder, T Knaflic
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Prediction of poor response to ursodeoxycholic acid in patients with primary biliary cholangitis by non-invasive markers [PDF]
Xin yixue, 2023 Objective To screen non-invasive indicators for predicting poor response to ursodeoxycholic acid in patients with primary biliary cholangitis（PBC）and establish a logistic regression model.
Gao Lili, Pan Shida, Zhang Yijin, Gao Xuesong, Su Nan, Xu Li, Duan Xuefei
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Molecules, 2023 As a first-line agent for cholestasis treatment in a clinic, ursodeoxycholic acid rectifies the perturbed bile acids (BAs) submetabolome in a holistic manner.
Wei Li +7 more
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The gut microbiota, bile acids and their correlation in primary sclerosing cholangitis associated with inflammatory bowel disease. [PDF]
, 2018 BACKGROUND: Patients with primary sclerosing cholangitis associated with inflammatory bowel disease (PSC-IBD) have a very high risk of developing colorectal neoplasia.
Bao, X +7 more
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