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Anti-inflammatory and antioxidant activity of ursolic acid: a systematic review and meta-analysis
Frontiers in Pharmacology, 2023 Introduction: There is currently evidence suggesting that ursolic acid may exert a favorable influence on both anti-inflammatory and antioxidant impact.
Man Zhao +6 more
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Cells, 2022 Cancer is one of the leading causes of death worldwide, thus the search for new cancer therapies is of utmost importance. Ursolic acid is a naturally occurring pentacyclic triterpene with a wide range of pharmacological activities including anti ...
Ditte L. Fogde +9 more
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Frontiers in Oncology, 2021 Breast cancer remains the most common malignancy and the leading causality of cancer-associated mortality among women worldwide. With proven efficacy, Oldenlandia diffusa has been extensively applied in breast cancer treatment in Traditional Chinese ...
Shengqi Wang +40 more
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Ursolic acid targets secreted phosphoprotein 1 to regulate Th17 cells against metabolic dysfunction-associated steatotic liver disease [PDF]
Clinical and Molecular HepatologyBackground/Aims Metabolic dysfunction-associated steatotic liver disease (MASLD) has become an increasingly important health challenge, with a substantial rise linked to changing lifestyles and global obesity.
Yiyuan Zheng +13 more
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Frontiers in Microbiology, 2021 Streptococcus mutans (S. mutans), the prime pathogen of dental caries, can secrete glucosyltransferases (GTFs) to synthesize extracellular polysaccharides (EPSs), which are the virulence determinants of cariogenic biofilms.
Yucui Liu +18 more
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Ursolic acid enhances macrophage autophagy and attenuates atherogenesis [PDF]
Journal of Lipid Research, 2016 Macrophage autophagy has been shown to be protective against atherosclerosis. We previously discovered that ursolic acid (UA) promoted cancer cell autophagy.
Fan, Daping +7 more
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Potential Pharmacological Properties of Triterpene Derivatives of Ursolic Acid. [PDF]
MoleculesUrsolic acid (UA) and its derivatives have garnered significant attention due to their extensive pharmacological activity. UA is a pentacyclic triterpenoid found in a variety of plants, such as apples, rosemary, thyme, etc., and it possesses a range of ...
Khwaza V, Aderibigbe BA.
europepmc +2 more sources
Therapeutic Potential of Ursonic Acid: Comparison with Ursolic Acid [PDF]
Biomolecules, 2020 Plants have been used as drugs to treat human disease for centuries. Ursonic acid (UNA) is a naturally occurring pentacyclic triterpenoid extracted from certain medicinal herbs such as Ziziphus jujuba. Since the pharmacological effects and associated mechanisms of UNA are not well-known, in this work, we attempt to introduce the therapeutic potential ...
Juhyeon Son, Sang Yeol Lee
openaire +4 more sources
Nanoparticles use for Delivering Ursolic Acid in Cancer Therapy: A Scoping Review
Frontiers in Pharmacology, 2021 Ursolic acid is a natural pentacyclic triterpenoid that exerts a potent anticancer effect. Furthermore, it is classified as a BCS class IV compound possessing low permeability and water solubility, consequently demonstrating limited bioavailability in ...
Andang Miatmoko +4 more
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Ursolic Acid Inhibits Collagen Production and Promotes Collagen Degradation in Skin Dermal Fibroblasts: Potential Antifibrotic Effects [PDF]
BiomoleculesTissue fibrosis, characterized by excessive collagen accumulation, leads to impaired organ function and is a hallmark of various chronic diseases. Fibroblasts play a central role in collagen production and deposition.
Tianyuan He +5 more
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