Results 11 to 20 of about 5,145,076 (274)

Ursolic acid attenuates oligospermia in busulfan-induced mice by promoting motor proteins [PDF]

open access: yesPeerJ
Background Oligospermia is one of the most common reasons for male infertility which is troubling numerous couples of child-bearing age. This investigation scrutinizes the implications and mechanistic underpinnings of ursolic acid’s effect on busulfan ...
Jin Dong   +4 more
doaj   +3 more sources

Extraction and Purification of Ursolic Acid from the Apple Peel and in vitro Assessment of the Biochemical Antibacterial, Antioxidant and Wound Healing Characteristics

open access: yesApplied Food Biotechnology, 2021
Background and Objective: Ursolic acid is a pentacyclic triterpenoid with various biological characteristics. The objective of this study was to investigate potentially biological activities of ursolic acid extracted from apple peels.
Fatemeh Ghasemzadeh   +2 more
doaj   +1 more source

Ursolic Acid Alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway

open access: yesInternational Journal of Molecular Sciences, 2023
The neuroinflammatory response after intracerebral hemorrhage (ICH) causes a large amount of neuronal loss, and inhibiting the inflammatory response can improve the prognosis.
Pan Lei   +6 more
semanticscholar   +1 more source

Ursolic acid: biological functions and application in animal husbandry

open access: yesFrontiers in Veterinary Science, 2023
Ursolic acid (UA) is a plant-derived pentacyclic triterpenoid with 30 carbon atoms. UA has anti-inflammatory, antioxidative, antimicrobial, hepato-protective, anticancer, and other biological activities.
Guanhui Liu   +5 more
semanticscholar   +1 more source

Topical Formulations Based on Ursolic Acid-Loaded Nanoemulgel with Potential Application in Psoriasis Treatment

open access: yesPharmaceutics, 2023
Psoriasis is a chronic disorder that causes a rash with itchy, scaly patches. It affects nearly 2–5% of the worldwide population and has a negative effect on patient quality of life.
Małgorzata Miastkowska   +13 more
semanticscholar   +1 more source

Ursolic Acid against Prostate and Urogenital Cancers: A Review of In Vitro and In Vivo Studies

open access: yesInternational Journal of Molecular Sciences, 2023
Prostate cancer is the second most diagnosed form of cancer in men worldwide and accounted for roughly 1.3 million cases and 359,000 deaths globally in 2018, despite all the available treatment strategies including surgery, radiotherapy, and chemotherapy.
Amanda Kornel   +8 more
semanticscholar   +1 more source

Electrospun Chitosan–Polyvinyl Alcohol Nanofiber Dressings Loaded with Bioactive Ursolic Acid Promoting Diabetic Wound Healing

open access: yesNanomaterials, 2022
The design and development of novel dressing materials are urgently required for the treatment of chronic wounds caused by diabetic ulcers in clinics. In this study, ursolic acid (UA) extracted from Chinese herbal plants was encapsulated into electrospun
Hongyu Lv   +7 more
semanticscholar   +1 more source

Anti-Planktonic and Anti-Biofilm Properties of Pentacyclic Triterpenes—Asiatic Acid and Ursolic Acid as Promising Antibacterial Future Pharmaceuticals

open access: yesBiomolecules, 2022
Due to the ever-increasing number of multidrug-resistant bacteria, research concerning plant-derived compounds with antimicrobial mechanisms of action has been conducted.
Zuzanna Sycz   +2 more
semanticscholar   +1 more source

Effect of Anti-Obesity and Antioxidant Activity through the Additional Consumption of Peel from ‘Fuji’ Pre-Washed Apple

open access: yesFoods, 2022
There is limited information on the health effects of apple peel taken from ‘Fuji’ (Malus pumila Mill) apples washed with ozonated water. To clarify the health-promoting effects of peel, the triterpenoids (ursolic acid and oleanolic acid) were quantified
Da-Yeong Ko, Kang-Mo Ku
doaj   +1 more source

Ursolic acid: a natural modulator of signaling networks in different cancers

open access: yesCancer Cell International, 2022
Incidence rate of cancer is estimated to increase by 40% in 2030. Furthermore, the development of resistance against currently available treatment strategies has contributed to the cancer-associated mortality. Scientists are now looking for the solutions
Samee Zafar   +10 more
semanticscholar   +1 more source

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