Results 11 to 20 of about 20,067 (234)

A Combination of Xanthohumol and Ursolic Acid in the Diet Leads to Synergistic Inhibition of Prostate Cancer Progression. [PDF]

open access: yesMol Carcinog
ABSTRACT Prostate cancer (PCa) is the second most common cancer and second leading cause of cancer death for American men. Chemoprevention by using phytochemicals offers a promising approach to improve outcomes due to their ability to act on cancer cell metabolism and growth while maintaining low toxicity profiles.
Clark R   +6 more
europepmc   +2 more sources

Complexation between oleanolic and maslinic acids with native and modified cyclodextrins [PDF]

open access: yes, 2018
Oleanolic (OA) and maslinic (MA) acids are two natural triterpenoids with a wide range of beneficial effects for human health. However, their low solubility and permeability make their application in the food or industry difficult. The complexation of OA
López Miranda, Santiago
core   +2 more sources

Ursolic Acid Inhibits Na+/K+-ATPase Activity and Prevents TNF-α-Induced Gene Expression by Blocking Amino Acid Transport and Cellular Protein Synthesis

open access: yesBiomolecules, 2011
Pro-inflammatory cytokines, such as tumor necrosis factor (TNF)-α, induce the expression of a wide variety of genes, including intercellular adhesion molecule-1 (ICAM-1).
Takao Kataoka   +7 more
doaj   +1 more source

Antibacterial compounds of the cultivated Robusta coffee: Coffea canephora Pierre ex A. Froehner

open access: yesScientific African, 2022
The stems and leaves of robusta coffee, Coffea canephora Pierre ex A. Froehner, one of the traded Coffea species, yielded caffeine (1), lupeol (2), ursolic acid (3), 3β-acetyl oleanolic acid (4), friedelin (5), asperphernamate (6), squalene (7 ...
S.G. Mewaba   +11 more
doaj   +1 more source

Iridoid glucosides from Pentas lanceolata (Forssk.) Deflers growing on the Island of Sardinia [PDF]

open access: yes, 2014
The ethanolic extract of Pentas lanceolata (Forssk.) Deflers was investigated from a phytochemical point of view and in particular on the monoterpenoid glucosides content.
Bianco, Armandodoriano   +3 more
core   +1 more source

Therapeutic Potential of Ursonic Acid: Comparison with Ursolic Acid [PDF]

open access: yesBiomolecules, 2020
Plants have been used as drugs to treat human disease for centuries. Ursonic acid (UNA) is a naturally occurring pentacyclic triterpenoid extracted from certain medicinal herbs such as Ziziphus jujuba. Since the pharmacological effects and associated mechanisms of UNA are not well-known, in this work, we attempt to introduce the therapeutic potential ...
Juhyeon Son, Sang Yeol Lee
openaire   +3 more sources

Evaluation of Anti-Toxoplasma gondii Effect of Ursolic Acid as a Novel Toxoplasmosis Inhibitor

open access: yesPharmaceuticals, 2018
This study was carried out to evaluate the anti-parasitic effect of ursolic acid against Toxoplasma gondii (T. gondii) that induces toxoplasmosis, particularly in humans. The anti-parasitic effects of ursolic acid against T.
Won Hyung Choi, In Ah Lee
doaj   +1 more source

Protective effects of ursolic acid and luteolin against oxidative DNA damage include enhancement of DNA repair in Caco-2 cells [PDF]

open access: yes, 2010
Consumption of fruits and vegetables is associated with a reduced risk of developing a wide range of cancers including colon cancer. In this study, we evaluated the effects of two compounds present in fruits and vegetables, ursolic acid, a triterpenoid ...
Collins, Andrew R.   +2 more
core   +1 more source

The Pleiotropic Antibacterial Mechanisms of Ursolic Acid against Methicillin-Resistant Staphylococcus aureus (MRSA)

open access: yesMolecules, 2016
(1) Background: Several triterpenoids were found to act synergistically with classes of antibiotic, indicating that plant-derived chemicals have potential to be used as therapeutics to enhance the activity of antibiotics against multidrug-resistant ...
Chao-Min Wang   +3 more
doaj   +1 more source

Ursolic acid increases skeletal muscle and brown fat and decreases diet-induced obesity, glucose intolerance and fatty liver disease.

open access: yesPLoS ONE, 2012
Skeletal muscle Akt activity stimulates muscle growth and imparts resistance to obesity, glucose intolerance and fatty liver disease. We recently found that ursolic acid increases skeletal muscle Akt activity and stimulates muscle growth in non-obese ...
Steven D Kunkel   +7 more
doaj   +1 more source

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