Results 21 to 30 of about 20,067 (234)

Ursolic acid inhibits colistin efflux and curtails colistin resistant Enterobacteriaceae

AMB Express, 2019
Colistin resistance in Enterobacteriaceae especially Klebsiella pneumoniae and Escherichia coli is driving the evolution of pan drug resistant strains.
Niranjana Sri Sundaramoorthy, Harihar M. Mohan, Shankar Subramaniam, Thiagarajan Raman, Subramaniapillai Selva Ganesan, Aravind Sivasubamanian, Saisubramanian Nagarajan   +6 more
doaj   +1 more source

Antiangiogenic Activity of Ursolic Acid

Integrative Cancer Therapies, 2010
Angiogenesis, the formation of new capillaries from preexisting vessels, is essential for tumor progression. Ursolic acid inhibited the tumor-associated capillary formation in C57BL/6 mice induced by highly metastatic B16F-10 melanoma cells. The levels of serum vascular endothelial growth factor (VEGF), NO, and proinflammatory cytokines were ...
Manu, Kanjoormana, Girija, Kuttan
openaire   +2 more sources

Luteolin, quercetin and ursolic acid are potent inhibitors of proliferation and inducers of apoptosis in both KRAS and BRAF mutated human colorectal cancer cells [PDF]

, 2009
KRAS and BRAF mutations are frequent in colorectal carcinoma (CRC) and have the potential to activate proliferation and survival through MAPK/ERK and/or PI3K signalling pathways. Because diet is one of the most important determinants of CRC incidence and
Ferreira, Manuel Fernandes, Lima, Cristóvão F., Preto, Ana, Seruca, Raquel, Wilson, Cristina Pereira, Xavier, Cristina P. R.   +5 more
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Mechanism of Action of Ursolic Acid in Ameliorating Mitochondrial Dysfunction in Podocytes Induced by High Glucose [PDF]

Shipin Kexue
Objective: This study aimed to investigate the protective effects of ursolic acid on mitochondrial dysfunction in podocytes induced by high glucose and to explore the underlying mechanism.
GU Huixian, AYIXIAMU·Maitituoheti, WU Siyu, JIANG Xianglong, YAO Lan
doaj   +1 more source

Ursolic Acid Potentializes Conventional Therapy in Experimental Leishmaniasis [PDF]

Pathogens, 2020
Ursolic acid (UA) is a triterpene with a broad array of pharmacological activities. In leishmaniasis, UA killed different species of parasites, and it was active in the experimental model of cutaneous and visceral leishmaniasis. Thus, the objective of this work was to study the therapeutic efficacy of the conventional drugs amphotericin B (AmB) or ...
Jéssica Adriana Jesus, Thays Nicolli Fragoso da Silva, Eduardo Seiji Yamamoto, João Henrique G. Lago, Márcia Dalastra Laurenti, Luiz Felipe Domingues Passero   +5 more
openaire   +5 more sources

The Metabolic Changes of Artesunate and Ursolic Acid on Syrian Golden Hamsters Fed with the High-Fat Diet

Molecules, 2020
Artesunate was well known as an antimalarial drug. Our previous research found that it has hypolipidemia effects in rabbits fed with a high-fat diet, especially combined with ursolic acid.
Shichen Pu, Yumin Liu, Shan Liang, Pin Liu, Hongmei Qian, Qian Wu, Yuliang Wang   +6 more
doaj   +1 more source

Interaction of Natural Dietary and Herbal Anionic Compounds and Flavonoids with Human Organic Anion Transporters 1 (SLC22A6), 3 (SLC22A8), and 4 (SLC22A11) [PDF]

, 2013
Active components of complementary/alternative medicines and natural supplements are often anionic compounds and flavonoids. As such, organic anion transporters (OATs) may play a key role in their pharmacokinetic and pharmacological profiles, and ...
Sweet, Douglas H., Wang, Li
core   +3 more sources

Ursolic acid and luteolin-7-glucoside improves rat plasma lipid profile and increases liver glycogen content through glycogen synthase kinase-3 [PDF]

, 2010
In the present study, two phytochemicals - ursolic acid (UA) and luteolin-7-glucoside (L7G) - were assessed in vivo in healthy rats regarding effects on plasma glucose and lipid profile (total cholesterol, HDL and LDL), as well as liver glycogen content,
Alarcon-Aguilar, Baricevic, Cazarolli, Ciaraldi, Costacou, Eidi, Goodyear, Hertog, Janicsak, Jayaprakasam, Jung, Kastelein, Keppler, Kersten, Klover, Lee, Levetan, Lima, Lima, Lima, Lin, Mooradian, Nomura, Perfumi, Postic, Pratipanawatr, Ramos, Sá, Waltner-Law, Xavier, Yin   +30 more
core   +1 more source

Regulation of mitogen-activated protein kinase signaling pathway and proinflammatory cytokines by ursolic acid in murine macrophages infected with Mycobacterium avium

Infectious Disease Reports, 2020
Mycobacterium avium, one of the closest relatives of Mycobacterium tuberculosis (MTB), offers an advantage in studying MTB because of its tuberculosis-like effect in humans and host immune tolerance.
Dian Ayu Eka Pitaloka, Andrea M. Cooper, Aluicia Anita Artarini, Elin Yulinah Sukandar, Sophi Damayanti   +4 more
doaj   +1 more source

Counter-current chromatography for the separation of terpenoids: A comprehensive review with respect to the solvent systems employed [PDF]

, 2014
Copyright @ 2014 The Authors.This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.Natural ...
A Berthod, A Berthod, A Koch, A Li, A Marston, A Maurya, A Peng, A Sun, ALM Nasser, AM Martin, AS Engelberth, AS Graham, B Diallo, B Diallo, B Medhi, B Pinel, BCB dos Santos, BK Gosse, C Zhao, CR Cheng, D Agostinho, D Du, D Fisher, D Grancher, D Wang, D Wang, D Wu, D Zhao, E Mudge, F Chen, F Chen, F Chen, F Fullas, F Gutiérrez, F He, F Oka, F Qiu, F Xiang, F Yang, G Tian, G Tian, G Wang, G Yan, GD Brown, GG Rocha, H Knapp, H Wu, H Ye, H Ye, H Zhang, HB Li, HB Li, HB Li, HB Li, HT Lu, I Slacanin, IA Sutherland, IA Sutherland, IA Sutherland, Ian Garrard, IJ Garrard, IJ Garrard, IJ Garrard, IJ Ha, J Hu, J Huang, J Liang, J Liu, J Ma, J Peng, J Wang, J Wang, J Wang, J Xie, J Xie, J Xu, J Yan, JCT Silva, JH Lee, JP Fan, JT Fischedick, JT Fischedick, JT Fischedick, K Skalicka-Woźniak, KD Yoon, KD Yoon, Krystyna Skalicka-Woźniak, KY Yoo, M Gu, M Gu, M Hamzaoui, M Lechtenberg, M Liu, M Puertas Mejia, MP Gasper, N Acton, N Fischer, N Frighetto, O Shehzad, O Shehzad, O Shehzad, O Shirota, O Shirota, P Hewitson, PA Souza De, PK Ajikumar, Q Chen, Q Du, Q Du, Q Du, Q Du, Q Du, Q Du, Q Du, QB Han, QB Han, QB Han, R Aman, R Graziose, R Roscher, R Tsao, RTS Frighetto, S Baldermann, S Baldermann, S He, S Liu, S Shi, S Wu, S Wu, S Yao, S Yao, SM Kim, SS Cicek, SY Shi, T Abbott, VF Rodrigues, VGP Severino, VP da Silva, W He, X Cao, X Han, X Qi, X Shi, X Xiao, X Xin, XC Li, XH Xiao, XY Huang, Y Cheng, Y Cheng, Y Geng, Y Ikai, Y Ito, Y Ito, Y Ito, Y Ito, Y Jiang, Y Lu, Y Lu, Y Ma, Y Wang, Y Wei, Y Wei, Y Wei, Y Yang, Y Yang, Y Yuan, Y Zhang, Y Zhao, YW Ha, YW Ha, YY Dang, Z Jiang   +172 more
core   +2 more sources