Results 31 to 40 of about 20,067 (234)

Therapeutic potentials of Crataegus azarolus var. eu- azarolus Maire leaves and its isolated compounds

open access: yesBMC Complementary and Alternative Medicine, 2017
Background Hyperglycemia is a complicated condition accompanied with high incidence of infection and dyslipidemia. This study aimed to explore the phyto-constituents of Crataegus azarolus var.
Eman Abu-Gharbieh, Naglaa Gamil Shehab
doaj   +1 more source

Antibacterial and Antioxidant Activities of Ursolic Acid and Derivatives

open access: yesMolecules, 2014
Ursolic acid, an important bioactive compound, was isolated from ethanol extract of aerial parts of Sambucus australis. In order to develop bioactive ursolic acid derivatives, two semi-synthetic compounds were obtained through modification at C-3.
Patrícia G.G. do Nascimento   +7 more
doaj   +1 more source

Bioactivity-Guided Investigation of the Anti-Inflammatory Activity of Hippophae rhamnoides Fruits [PDF]

open access: yes, 2017
According to modern ethnobotanical records, the fruit of Hippophae rhamnoides is effective in the treatment of different allergic symptoms. In order to obtain pharmacological evidence for this observation, the fruit was investigated for anti-inflammatory
Blazsó, Gábor   +5 more
core   +1 more source

Ursolic acid in health and disease

open access: yesThe Korean Journal of Physiology & Pharmacology, 2018
Ursolic acid (UA) is a natural triterpene compound found in various fruits and vegetables. There is a growing interest in UA because of its beneficial effects, which include anti-inflammatory, anti-oxidant, anti-apoptotic, and anti-carcinogenic effects.
Seo, Dae Yun   +7 more
openaire   +2 more sources

Ursolic acid inhibits superoxide production in activated neutrophils and attenuates trauma-hemorrhage shock-induced organ injury in rats.

open access: yesPLoS ONE, 2014
Neutrophil activation is associated with the development of organ injury after trauma-hemorrhagic shock. In the present study, ursolic acid inhibited the superoxide anion generation and elastase release in human neutrophils.
Tsong-Long Hwang   +6 more
doaj   +1 more source

Investigating the combined effect of ursolic acid and alpelisib on inhibiting cell proliferation and the expression of HIF1α on 4T1 breast cancer cell line [PDF]

open access: yesJournal of Research in Applied and Basic Medical Sciences, 2023
Background & Aims:  Alpelisib and Ursolic acid are two compounds that have been shown to have potential as anti-cancer agents. Alpelisib is a selective inhibitor of the PI3K pathway, while Ursolic acid is a natural pentacyclic triterpene compound found ...
Erfan Sheikhi   +2 more
doaj  

Differential Anti-Proliferative and Anti-Migratory Activities of Ursolic Acid, 3-O-Acetylursolic Acid and Their Combination Treatments with Quercetin on Melanoma Cells

open access: yesBiomolecules, 2020
We evaluate how 3-acetylation modulates the in vitro activity of ursolic acid in melanoma cells alone or in combination treatments with quercetin. Anti-proliferative studies on A375 cells and adult human dermal fibroblasts included analyses on cell cycle
Aljawharah AlQathama   +5 more
doaj   +1 more source

In vitro evaluation of the comprehensive antimicrobial and antioxidant properties of Curtisia dentata (Burm.f) C.A. Sm: toxicological effect on the human embryonic kidney (HEK293) and human hepatocellular carcinoma (HepG2) cell lines [PDF]

open access: yes, 2015
Curtisia dentata is used in African traditional medicine to treat variety of infections. C. dentata leaves were collected from Buffelskloof Nature Reserve, South Africa.
Fadipe, VO, Mongalo, NI, Opoku, AR
core   +1 more source

Effects of Ursolic Acid and its Analogues on Soybean 15-Lipoxygenase Activity and the Proliferation Rate of A human Gastric Tumour Cell Line

open access: yesMediators of Inflammation, 1994
The authors have previously isolated and purified ursolic acid from heather flowers (Calluna vulgarts). This terpene was found to inhibit HL-60 leukaemic cell proliferation and arachidonic acid oxidative metabolism in various cell species. The effects of
D. Es-Saady   +5 more
doaj   +1 more source

Extraction of ursolic acid in Cornus officinalis by fermentation combined with ultrasonic-assisted technique

open access: yes浙江大学学报. 农业与生命科学版, 2009
The optimum extraction process of ursolic acid from the fermentation product of Cornus officinalis was screened by the aid of ultrasonic, and the yield of ursolic acid was monitored by HPLC techniques.
XU Bai-tao   +4 more
doaj   +1 more source

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