Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha+6 more
wiley +1 more source
Note on the use of Peirce's Criterion for the Rejection of Doubtful Observations [PDF]
S. A. Saunder
openalex +1 more source
A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini+11 more
wiley +1 more source
Less Complexity in Hemodialysis Machines Reduces Time and Physical Load for Operator Actions
Uwe Gründler,1 Eva Ekesbo,2 Martin Löwe,1 Adelheid Gauly3 1REFA Consulting AG, Dortmund, Germany; 2BetaHälsan AB, Lund, Sweden; 3Fresenius Medical Care, Global Medical Office, Bad Homburg, GermanyCorrespondence: Adelheid GaulyFresenius Medical Care ...
Gründler U, Ekesbo E, Löwe M, Gauly A
doaj
A critical analysis of cognitive load measurement methods for evaluating the usability of different types of interfaces: guidelines and framework for Human-Computer Interaction [PDF]
Usability testing is an essential part of product design, particularly for user interfaces. To enhance the reliability of usability evaluations, employing cognitive load measurement methods can be highly effective in assessing the mental effort required to complete tasks during user testing.
arxiv
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi+6 more
wiley +1 more source
On the usability of generative AI: Human generative AI [PDF]
Generative AI systems are transforming content creation, but their usability remains a key challenge. This paper examines usability factors such as user experience, transparency, control, and cognitive load. Common challenges include unpredictability and difficulties in fine-tuning outputs.
arxiv
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke+12 more
wiley +1 more source
Automatic web site quality evaluation tools: Emphasis upon Usability [PDF]
Web information usability is a new issue, which has attracted many specialists in these days. It has been of great importance regarding the increasing growth of web sites requiring quality monitoring.
Nafiseh Changiz
doaj