Results 131 to 140 of about 698,130 (295)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Scenario-Based Immersive Virtual Reality Platform for Testing Empathy Types: A Development Study

IEEE Access
Empathy skills are required for understanding and responding to others’ emotions. Traditional instruments for testing a person’s empathy type lack immersion and contain recall bias.
Teemu H. Laine, Woohyun Lee, Jiyoung Moon, Aziz Hasanov, Hae Jung Suk   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

How relevant are personas in open-source software development?

Frontiers in Computer Science
IntroductionOpen-source software (OSS) projects, characterized by distributed development and volunteer contributions, face challenges in prioritizing user-centered design and usability.
Ahmed Chelly, Salma Hamza, Javed Ali Khan   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Study Area Map Generator: A Web-Based Shiny Application for Generating Country-Level Study Area Maps for Scientific Publications

ISPRS International Journal of Geo-Information
The increasing demand for high-quality geospatial visualizations in scientific publications has highlighted the need for accessible and standardized tools that support reproducible research. Researchers from various disciplines—often without expertise in
Cesar Ivan Alvarez, Juan Gabriel Mollocana-Lara, Izar Sinde-González, Ana Claudia Teodoro   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Usability

Im KONDE-Projekt, das aus Hochschulraumstrukturmitteln finanziert wird, beschäftigten sich sieben universitäre Partner und drei weitere Einrichtungen aus unterschiedlichen Blickwinkeln mit theoretischen und praktischen Aspekten der Digitalen Edition. Ein Outcome des Projektes stellt das Weißbuch dar, welches über 200 Artikel zum Thema Digitale Edition ...
  +5 more sources

Improving Perception of Usability Through User Interface Design Patterns to Optimize Information Architecture for Cognitive Benefits and User Satisfaction in Massive Open Online Courses

IEEE Access
This study explores the impact of user interface design patterns on usability, cognitive load, and user satisfaction for Massive Open Online Courses using small-screen devices.
Tahir Farooq, C. M. Nadeem Faisal, Javier De Andres, Zafar Saeed, Sajid Anwer, Toqeer Mahmood   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source