Results 61 to 70 of about 715,050 (330)

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

The Technical Development of a Prototype Lower-Limb Therapy Device for Bed-Resting Users

Actuators
It is generally recommended that bed-resting patients be mobilised early to promote recovery. The aim of this work was to develop and evaluate the usability of a prototype in-bed lower-limb therapy device that offers various training patterns for the ...
Juan Fang, Adrien Cerrito, Simón Gamero Schertenleib, Patrick von Raumer, Kai-Uwe Schmitt   +4 more
doaj   +1 more source

Teaching Python with team‐based learning: using cloud‐based notebooks for interactive coding education

FEBS Open Bio, EarlyView.
This study presents a novel approach to teaching Python and bioinformatics using team‐based learning and cloud‐hosted notebooks. By integrating interactive coding into biomedical education, the method improves accessibility, student engagement, and confidence—especially for those without a computing background.
Nuno S. Osório, Leonardo D. Garma
wiley   +1 more source

A Review of Brain-Computer Interface Games and an Opinion Survey from Researchers, Developers and Users

Italian National Conference on Sensors, 2014
In recent years, research on Brain-Computer Interface (BCI) technology for healthy users has attracted considerable interest, and BCI games are especially popular. This study reviews the current status of, and describes future directions, in the field of
M. Ahn, Mi-Jin Lee, Jinyoung Choi, S. Jun   +3 more
semanticscholar   +1 more source

A Comparative Study on Iranian Journal Management Systems in Universities of Medical Sciences Based on the Usability Components

مدیریت اطلاعات سلامت, 2020
مقدمه: به دلیل توسعه کاربردپذیری سامانه‌های مدیریت نشریات ادواری دانشگاه‌های علوم پزشکی کشور که از پرمخاطب‌ترین سامانه‌های دانشگاهی به شمار می‌روند و همچنین، عدم وجود مطالعات مرتبط، پژوهش حاضر با هدف تعیین هشت مؤلفه کاربردپذیری سیستم‌ها و مقایسه سامانه ...
Amir Mohamad Mozafari-Vanani, Rasool Nouri, Akbar Hassanzadeh, Alireza Rahimi   +3 more
doaj   +1 more source

Structural and functional characterization of chitinase from carnivorous plant Drosera adelae

FEBS Open Bio, EarlyView.
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda, Yuki Naruse, Yusaku Suizu, Tomohiro Araki, Yoshikazu Hoshi, Haruhiko Sakuraba, Junji Hayashi, Toshihisa Ohshima   +7 more
wiley   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Functional Characterization and Pathogenicity Classification of PRRT2 Splice Variants in PRRT2‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Paroxysmal kinesigenic dyskinesia (PKD) is the most common hereditary paroxysmal movement disorder. The PRRT2 gene is the first identified causative gene and accounts for the majority of PKD. In this study, we investigated the pathogenicity of PRRT2 variants in the splice regions. Methods Patients with clinically suspected PKD and no
Jiao‐Jiao Xu, Yu‐Lan Chen, Wan‐Bing Sun, Hong‐Fu Li, Zhi‐Ying Wu, Dian‐Fu Chen   +5 more
wiley   +1 more source

Human Computer Interaction

Lecture Notes in Computer Science, 2015
The intention of this paper is to provide an overview on the subject of Human-Computer Interaction(HCI). Human-computer interaction basically covers the concepts of humans interacting with computers, but computers do not understand our feelings or ...
Hau-San Wong, H. Ip
semanticscholar   +1 more source

Finger-stylus for non touch-enable systems

Journal of King Saud University: Engineering Sciences, 2017
Since computer was invented, people are using many devices to interact with computer. Initially there were keyboard, mouse etc. but with advancement of technology, new ways are being discovered that are quite common and natural to the humans like stylus ...
Ankit Chaudhary
doaj   +1 more source