Results 91 to 100 of about 984,321 (234)

Práticas Didáticas de Ensino, Pesquisa, Cultura e Extensão Universitária no Parque CienTec-USP: O Projeto Solo na Escola-Geografia-USP

, 2017
Este relato apresenta o projeto intitulado Solo na Escola-Geografia-USP como parte de atividades de pesquisa, cultura e extensão universitária, voltadas a divulgar o solo e sua importância por meio de práticas não formais, e sim lúdicas e didáticas.
Oliveira, Déborah de, Déborah De Oliveira   +1 more
core   +1 more source

Graphene oxide–modified fluoridated varnish promotes mineral recovery in demineralized bovine enamel: An in vitro study

European Journal of Oral Sciences, EarlyView.
Abstract This in vitro study evaluated the efficacy of an experimental fluoridated varnish modified with graphene oxide (GO) nanoparticles in arresting initial caries lesion progression and promoting mineral recovery in demineralized bovine enamel.
Mariana Souza Rodrigues, Guilherme José Drigo, Sofia Furlanete Raymundo, Nair Cristina Brondino, Salvatore Sauro, Marilia Mattar de Amoêdo Campos Velo   +5 more
wiley   +1 more source

Caffeylpyruvate hydrolase from the bioluminescent fungus Neonothopanus gardneri is the key recycling enzyme in the fungal bioluminescence pathway

The FEBS Journal, EarlyView.
Caffeic acid is a central metabolite in the fungal bioluminescence pathway. We identified and characterized caffeylpyruvate hydrolase from Neonothopanus gardneri (ngarCPH) and demonstrate its ability to hydrolyze fungal oxyluciferin into caffeic and pyruvic acids, confirming a complete and self‐sustained fungal bioluminescence cycle.
Caio K. Zamuner, Douglas M. M. Soares, Bianca B. Nóbrega, Etelvino J. H. Bechara, Zinaida M. Kaskova, Alexander S. Mishin, Karen S. Sarkisyan, Ilia V. Yampolsky, Cassius V. Stevani   +8 more
wiley   +1 more source

The broad-spectrum deubiquitinating enzyme inhibitor PR-619 protects retinal ganglion cell and augments parkin-mediated mitophagy in experimental glaucoma

Scientific Reports
Glaucoma is a leading cause of irreversible visual impairment worldwide, characterized by the progressive death of retinal ganglion cells (RGCs).
Xinxin Hu, Juntao Zhang, Haixia Ma, Wei Lian, Wenqiu Song, Chao Du, Shengcan Chen, Dandan Wang, Jiaqi Wei, Qinkang Lu   +9 more
doaj   +1 more source

Fluoride‐Free Mouthwashes Available Over‐The‐Counter in the US‐An Overview

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Purpose Fluoride‐free mouthwashes (FFM) are commonly used by patients for a variety of cosmetic and/or therapeutic reasons. The purpose of this study was to investigate the composition and purposes of FFM available over‐the‐counter in the US.
Astrid C. Valdivia‐Tapia, Jaime A. Cury, Antonio P. Ricomini‐Filho, Frank Lippert   +3 more
wiley   +1 more source

LAPTM4B enhances the stemness of CD133+ liver cancer stem-like cells via WNT/β-catenin signaling

JHEP Reports
Background & Aims: Lysosome-associated protein transmembrane 4β (LAPTM4B) is an oncogene implicated in the malignant progression of hepatocellular carcinoma (HCC).
Jiahong Wang, Jianping Liao, Ye Cheng, Meirong Chen, Aimin Huang   +4 more
doaj   +1 more source

USP30 inhibits wound healing in diabetic foot ulcers by promoting TRAF6‐induced ferroptosis and angiogenesis inhibition

Journal of Diabetes Investigation, EarlyView.
High glucose upregulates USP30 in HUVECs, which deubiquitinates and stabilizes TRAF6. Stabilized TRAF6 suppresses GPX4 and SLC7A11, increases ROS/MDA/lipid peroxidation, and activates ferroptosis and apoptosis, leading to impaired angiogenesis and delayed wound healing.
Jingjing Yuan, Shuang Sui, Zhenghua Yang, Kaiwen Zhang, Qiang Hu   +4 more
wiley   +1 more source

CONCEPÇÃO E GERENCIMENTO DE PROJETO: A AMPLIAÇÃO DE ATIVIDADES E DE PESQUISAS EM MONUMENTO UNIVERSITÁRIO TOMBADO (O MONUMENTO NACIONAL RUÍNAS ENGENHO SÃO JORGE DOS ERASMOS - PRCEU-USP) [PDF]

, 2015
Este artigo aponta as estratégias adotadas para aumentar o potencial de visitantes e retomar as pesquisas históricas e arqueológicas no Monumento Nacional Ruínas Engenho São Jorge dos Erasmos, da Pró-Reitoria de Cultura e Extensão Universitária da ...
MELLO, ANDRÉ MULLER DE, CAMPOS, ANNA MARIA COELHO SILVA DE, SILVA, TATHIANNI CRISTINI DA, CHRISTOFOLETTI, RODRIGO, JORDÃO, BEATRIZ PACHECO, FERLINI, VERA LÚCIA AMARAL   +5 more
core  

Concurrent Use of Tasipimidine Oral Solution and Fluoxetine in Dogs

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT This exploratory randomized crossover study investigated pharmacokinetic interactions, functional alertness, and cardiovascular safety of tasipimidine oral solution administered alone and in combination with fluoxetine in healthy Beagle dogs (n = 8; 4 dogs per dose level), with a 7‐day washout between phases. Dogs received single oral doses of
Jenni Lindstedt, Jouko M. Levijoki, Johanna Tuunainen, Jens Häggström, Meri Ramela, Mira Korpivaara   +5 more
wiley   +1 more source

LabSid-USP/RUBEMHydrological: RUBEM Hydrological v1.12.3-beta.3

<h2>What's Changed</h2> <ul> <li>Fix <code>plotTimeSeriesData function</code> to use numpy arrays for plotting by @soaressgabriel in https://github.com/LabSid-USP/RUBEMHydrological/pull/136</li> </ul> <p&
camilabillerbeck, wdvichete84, Daniel Manabe Pasetti, LINA OSORIO, Gabriel Soares   +4 more
core   +1 more source