Results 111 to 120 of about 491,422 (252)

Single--crossover recombination in discrete time

, 2009
Modelling the process of recombination leads to a large coupled nonlinear dynamical system. Here, we consider a particular case of recombination in {\em discrete} time, allowing only for {\em single crossovers}.
Baake, Ellen, Baake, Michael, von Wangenheim, Ute   +2 more
core   +1 more source

Absolute Quantification of Brain Deuterium Metabolic Imaging in Healthy Volunteers and Glioblastoma Patients at 7T

Magnetic Resonance in Medicine, Volume 95, Issue 6, Page 3077-3094, June 2026.
ABSTRACT Purpose We present a method for absolute quantification of deuterated metabolites in vivo at 7T. We describe acquisition protocols and an analysis pipeline compatible with 7T Terra MRIs. We apply them using a 2H/1H receive array in healthy volunteers and glioblastoma patients.
Jabrane Karkouri, Masha Novoselova, Sarah Miller, Minghao Zhang, Alexandra Constantinou, Carina Graf, Özlem Ipek, Daniel Atkinson, Brandon Tramm, Scott Schillak, Richard Mair, Kevin Brindle, Christopher T. Rodgers   +12 more
wiley   +1 more source

Data‐Driven Characterization of Knee Structures Using Non‐Negative Matrix Factorization of 3D Multi‐Echo UTE MRI

NMR in Biomedicine, Volume 39, Issue 6, June 2026.
Non‐negative matrix factorization (NMF) can derive tissue features in a data‐driven manner without relying on biophysical model assumptions. First‐time application of NMF to 3D multi‐echo UTE knee MRI revealed four reproducible components associated with tissues of fast and slow transverse relaxation, water–fat mixture (chemical shift), and fat tissue.
Céline Smekens, Pieter Van Dyck, Patrick S. Fuchs, Jan Sijbers, Thomas Janssens, Ben Jeurissen   +5 more
wiley   +1 more source

Nec ut interpres sed ut... philosophus

Calenda
Par le colloque international « Nec ut interpres sed ut… philosophus : pourquoi éditer et commenter encore les textes philosophiques cicéroniens ? », nous nous fixions un objectif novateur dans l’univers philologique au sens large du terme : offrir un point de rencontre de différents horizons méthodologiques avec une approche kaléidoscopique du Corpus ...
openaire   +3 more sources

The Evolution of Diversity [PDF]

, 2017
Since the beginning of time, the pre-biological and the biological world have seen a steady increase in complexity of form and function based on a process of combination and re-combination.
Beckley, Colin, Bonillas, Ute
core  

Preclinical Quantitative In Vivo MRI Assessment of Exogenous Surfactant Pulmonary Distribution After Clinically Relevant Intratracheal Delivery

NMR in Biomedicine, Volume 39, Issue 6, June 2026.
Quantitative in vivo contrast‐enhanced UTE MRI enables sensitive and precise mapping of pulmonary surfactant distribution, revealing peripheral localization and homogeneous distal penetration under physiological conditions. Comparison with ex vivo models highlights the role of physiological processes in surfactant retention.
Oumaima Marfouk, Rémy Gérard, Ghalia Kaouane, Lara Leclerc, Noël Pinaud, Michael Fayon, Sophie Périnel‐Ragey, Jérémie Pourchez, Eric Dumas De La Roque, Yannick Crémillieux   +9 more
wiley   +1 more source

Reducing Noise Induced by Cardiac Pulsatility in Brain Maps of R2* and Magnetic Susceptibility Using Tailored k‐space Sampling

NMR in Biomedicine, Volume 39, Issue 6, June 2026.
With linear k‐space sampling trajectories, cardiac pulsation leads to MRI signal instabilities that increase the variability (standard deviation, SD) of R2* and QSM maps across repetitions. Here, we propose alternative trajectories that aim to mitigate the impact of cardiac‐induced noise in brain maps of R2* and QSM.
Quentin Raynaud, Thomas Dardano, Rita Oliveira, Giulia Di Domenicantonio, Tobias Kober, Christopher W. Roy, Ruud B. van Heeswijk, Antoine Lutti   +7 more
wiley   +1 more source

Comparison of diagnostic performance for pulmonary nodule detection between free-breathing spiral ultrashort echo time and free-breathing radial volumetric interpolated breath-hold examination

BMC Medical Imaging
Objective This study aims to evaluate the efficacy of two free-breathing magnetic resonance imaging (MRI) sequences—spiral ultrashort echo time (spiral UTE) and radial volumetric interpolated breath-hold examination (radial VIBE).
Yehai Jiang, Doudou Pu, Xuyang Zhang, Zhanli Ren, Nan Yu   +4 more
doaj   +1 more source

Estimation of Trabecular Bone Volume with Dual-Echo Ultrashort Echo Time (UTE) Magnetic Resonance Imaging (MRI) Significantly Correlates with High-Resolution Computed Tomography (CT)

Journal of Imaging
Trabecular bone architecture has important implications for the mechanical strength of bone. Trabecular elements appear as signal void when imaged utilizing conventional magnetic resonance imaging (MRI) sequences.
Karen Y. Cheng, Dina Moazamian, Behnam Namiranian, Hamidreza Shaterian Mohammadi, Salem Alenezi, Christine B. Chung, Saeed Jerban   +6 more
doaj   +1 more source

Development and Structural Characterization of UTE‐156, a Covalent Inhibitor of the VCP/p97 AAA+ ATPase

Advanced Science, Volume 13, Issue 25, 4 May 2026.
The AAA+ ATPase Valosin‐containing protein (VCP/p97) regulates protein homeostasis by unfolding ubiquitinated substrates. Here, we describe UTE‐156, a novel irreversible covalent inhibitor that modifies Cys522 in the D2 ATPase motor domain. Although its pharmacochemical limitations preclude immediate therapeutic use, UTE‐156 serves as a valuable ...
Daniela Tamayo‐Jaramillo, Subramanya Hegde, Xuan Jia, Kimberly Coffman, Hariprasad Vankayalapati, David Bearss, Kevin B. Jones, Alex W. Stark, Peter S. Shen   +8 more
wiley   +1 more source