Results 61 to 70 of about 1,356,159 (307)
Neurobiological studies of risk assessment: A comparison of expected utility and mean-variance approaches [PDF]
, 2008 When modeling valuation under uncertainty, economists generally prefer expected utility because it has an axiomatic foundation, meaning that the resulting choices will satisfy a number of rationality requirements.
Bossaerts, Peter, d'Acremont, M.
core +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
A Utilitarian Decision—Making Approach for Front End Design—A Systematic Literature Review
Buildings, 2020 The complexity of construction processes often means interaction between various stakeholders, activities and tasks in order to deliver the expected outcomes.
Joas Serugga +2 more
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Measurement Theory and the Foundations of Utilitarianism [PDF]
Harsanyi used expected utility theory to provide two axiomatizations of weighted utilitarian rules. Sen (and later, Weymark) has argued that Harsanyi has not, in fact, axiomatized utilitarianism because he has misapplied expected utility theory ...
John a. Weymark
core
The Shannon information of filtrations and the additional logarithmic utility of insiders [PDF]
, 2005 The background for the general mathematical link between utility and information theory investigated in this paper is a simple financial market model with two kinds of small traders: less informed traders and insiders, whose extra information is ...
Ankirchner, Stefan +2 more
core +5 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Allergology International, 2009 Background: Allergic rhinitis is not a fatal disease, but its symptoms deteriorate the quality of life. High morbidity raises a concern about its impact on health care resources.
Kazuhiro Tamayama +3 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A cumulative prospect theory approach to car owner mode choice behaviour prediction
Transport, 2014 The uncertain transportation environment makes travel’s mode choice decision-making behaviour become a complex and alterable process. Based on the cumulative prospect theory, this paper analysed the long-standing use of utility theory for the travel’s ...
Shi An, Xiaowei Hu, Jian Wang
doaj +1 more source