Results 91 to 100 of about 9,678 (222)

Mixed Gonadal Dysgenesis: A Comprehensive Review of Clinical Spectrum, Diagnostic Strategies, and Management Approaches

open access: yesClinical Endocrinology, Volume 104, Issue 2, Page 92-102, February 2026.
ABSTRACT Background Mixed gonadal dysgenesis (MGD) is a rare form of differences in sex development (DSD) typically associated with 45,X/46,XY mosaicism. The phenotypic presentation of MGD varies from atypical genitalia to typical male or female appearances often associated with Turner stigmata.
Dinesh Giri   +6 more
wiley   +1 more source

Characterization of Wnt and Notch-Responsive Lgr5+ Hair Cell Progenitors in the Striolar Region of the Neonatal Mouse Utricle

open access: yesFrontiers in Molecular Neuroscience, 2018
Dysfunctions in hearing and balance are largely connected with hair cell (HC) loss. Although regeneration of HCs in the adult cochlea does not occur, there is still limited capacity for HC regeneration in the mammalian utricle from a distinct population ...
Dan You   +8 more
doaj   +1 more source

Auditory neuroscience: Development, transduction and integration [PDF]

open access: yes, 2000
Hearing underlies our ability to locate sound sources in the environment, our appreciation of music, and our ability to communicate. Participants in the National Academy of Sciences colloquium on Auditory Neuroscience: Development, Transduction, and ...
Hudspeth, A. J., Konishi, Masakazu
core  

An RNA interference-based screen of transcription factor genes identifies pathways necessary for sensory regeneration in the avian inner ear [PDF]

open access: yes, 2011
Sensory hair cells of the inner ear are the mechano-electric transducers of sound and head motion. In mammals, damage to sensory hair cells leads to hearing or balance deficits.
Alvarado, David M   +9 more
core   +2 more sources

Conditional and constitutive expression of a Tbx1-GFP fusion protein in mice. [PDF]

open access: yes, 2013
BACKGROUND: Velo-cardio-facial syndrome/DiGeorge syndrome (VCFS/DGS) is caused by a 1.5-3 Mb microdeletion of chromosome 22q11.2, frequently referred to as 22q11.2 deletion syndrome (22q11DS).
Baldini, Antonio   +4 more
core   +1 more source

Canal switch after canalith repositioning procedure for benign paroxysmal positional vertigo [PDF]

open access: yes, 2012
Canal switch is a complication following canalith repositioning procedure (CRP) for posterior canal benign paroxysmal positional vertigo (BPPV). Instead of being returned to the utricle, the loose otoconia migrate into the superior or horizontal ...
Basura, Gregory J.   +3 more
core   +1 more source

TMC function, dysfunction, and restoration in mouse vestibular organs

open access: yesFrontiers in Neurology
Tmc1 and Tmc2 are essential pore-forming subunits of mechanosensory transduction channels localized to the tips of stereovilli in auditory and vestibular hair cells of the inner ear.
Evan M. Ratzan   +7 more
doaj   +1 more source

Micromotional studies of utricular and canal afferents [PDF]

open access: yes
The long-range goal of this research was to refine our understanding of the sensitivity of the vestibular components of the ear to very-low-amplitude motion, especially, the role of gravity in this sensitivity.
Lewis, Edwin R.
core   +1 more source

Stereociliary Myosin-1c Receptors Are Sensitive to Calcium Chelation and Absent from Cadherin 23 Mutant Mice [PDF]

open access: yes, 2006
The identities of some of the constituents of the hair-cell transduction apparatus have been elucidated only recently. The molecular motor myosin-1c (Myo1c) functions in adaptation of the hair-cell response to sustained mechanical stimuli and is ...
Cyr, Janet L   +4 more
core   +1 more source

PLURIPOTENT STEM CELLS FROM THE ADULT MOUSE UTRICLE

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Researchers discovered that cochlear epithelia in mice especially the vestibular one, contains stem cells that have the capacity to differentiate in sensorial auditory hair cell progenitors specific to the organ.
ROXANA DANIELA VINTILĂ   +8 more
doaj  

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