Results 61 to 70 of about 914 (177)

Is CABP2‐Associated Hearing Loss (DFNB93) a Gene Therapy Target? Preclinical Progress and Patient Registry

open access: yesMedComm, Volume 6, Issue 9, September 2025.
The intended aims and benefits of the CABP2 Patient Registry. ABSTRACT CABP2 modulates presynaptic CaV1.3 Ca2+ channel function in inner hair cells (IHCs) and is required for indefatigable synaptic sound encoding. Biallelic variants in CABP2 are associated with non‐syndromic hearing loss (DFNB93).
Barbara Vona   +4 more
wiley   +1 more source

Application of utricle function testing in different clinical stages of Meniere’s disease

open access: yesZhongguo Linchuang Yixue
ObjectiveTo explore the role of ocular vestibular evoked myogenic potential (oVEMP) and unilateral centrifugation subjective visual vertical (UC-SVV) tests in evaluating the utricular function of patients with Meniere’s disease (MD) at different clinical
Yuanling LI   +5 more
doaj   +1 more source

Semicircular Canal Influences on the Developmental Tuning of the Translational Vestibulo-Ocular Reflex

open access: yesFrontiers in Neurology, 2018
Vestibulo-ocular reflexes (VORs) rely on neuronal computations that transform vestibular sensory signals into spatio-temporally appropriate extraocular motor commands.
Francisco Branoner, Hans Straka
doaj   +1 more source

A 30-year retrospective study of rare ectopic seminal tract opening cases

open access: yesAsian Journal of Andrology, 2020
Ectopic seminal tract opening is a rare congenital malformation. Until recently, there has been a lack of comprehensive reporting on the condition. The purpose of this retrospective study is to summarize the experience of diagnosis and treatment of this ...
Hong-Fei Wu   +6 more
doaj   +1 more source

Development of Synaptic Innervation in the Rodent Utricle [PDF]

open access: yesAnnals of the New York Academy of Sciences, 1999
We decided to reexamine early postnatal synaptic innervation in relation to ongoing studies of the development of physiological, morphological, and molecular features of hair cells in the mouse utricular macula.1,2 Physiological studies 3,4 demonstrated that mammalian type I and type II hair cells have distinctively different potassium conductances ...
openaire   +3 more sources

Risk of Benign Paroxysmal Positional Vertigo Modified by Diuretics—A Population‐Level Case‐Control Study

open access: yesOtolaryngology–Head and Neck Surgery, Volume 173, Issue 3, Page 613-625, September 2025.
Abstract Objective This study aims to characterize diuretic use among patients with and without benign paroxysmal positional vertigo (BPPV) using a population‐level database. Study Design A case‐control study. Setting TriNetX US Collaborative Network. Methods Subjects with ≥1 hospital visit between 2019 and 2024 were queried and stratified by age (18 ...
Marwin Li   +2 more
wiley   +1 more source

Analysis of subjective visual vertical test results in patients with benign paroxysmal positional vertigo at different head deflection angles

open access: yesZhongguo Linchuang Yixue
ObjectiveTo analyze the clinical significance of subjective visual vertical (SVV) tests at different head deflection angles in assessing utricle function in patients with benign paroxysmal positional vertigo (BPPV). MethodsA total of 61 BPPV patients who
Maolin QIN   +8 more
doaj   +1 more source

Update on Gene Therapy in the Treatment of Hereditary Hearing Loss

open access: yesSensory Neuroscience, Volume 1, Issue 2, September 2025.
Gene therapy is a promising therapeutic approach for genetic disorders, including three major gene therapy strategies: gene replacement, gene suppression, and gene editing. After transmitting genes to the inner ear through appropriate pathways, repair the cochlea in order to achieve the goal of treating hereditary hearing loss.
Weiwei He   +7 more
wiley   +1 more source

TMC function, dysfunction, and restoration in mouse vestibular organs

open access: yesFrontiers in Neurology
Tmc1 and Tmc2 are essential pore-forming subunits of mechanosensory transduction channels localized to the tips of stereovilli in auditory and vestibular hair cells of the inner ear.
Evan M. Ratzan   +7 more
doaj   +1 more source

PLURIPOTENT STEM CELLS FROM THE ADULT MOUSE UTRICLE

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Researchers discovered that cochlear epithelia in mice especially the vestibular one, contains stem cells that have the capacity to differentiate in sensorial auditory hair cell progenitors specific to the organ.
ROXANA DANIELA VINTILĂ   +8 more
doaj  

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