Results 41 to 50 of about 5,195 (181)
A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside
Interdisciplinary Medicine, EarlyView.This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione +2 more
wiley +1 more source
A Rare Case of Prostatic Utricle with Crossover Vas Deferens in Children
Medicina, 2021 Background: A prostatic utricle (PU) is an unusual pathology with most patients being asymptomatic. However, approximately 29% of patients may show lower urinary tract symptoms, recurrent urinary tract infections (UTI), postvoid dribbling, urethral ...
Tsung-Heng Wu +3 more
doaj +1 more source
Labyrinthine Abnormalities on MRI in Untreated Otosclerosis: Prevalence and Clinical Relevance
The Laryngoscope, EarlyView.In untreated otosclerosis with labyrinthine symptoms, delayed 3D FLAIR MRI rarely demonstrates endolymphatic hydrops but frequently reveals blood–labyrinth barrier (BLB) disruption. BLB enhancement is spatially associated with cochlear endosteal and round window involvement and increases with the severity of the hearing loss phenotype.
Héléna Pencroffi +7 more
wiley +1 more source
Successful treatment of recurrent epididymo-orchitis: Laparoscopic excision of the prostatic utricle
Journal of Indian Association of Pediatric Surgeons, 2009 Prostatic utricle presenting with recurrent epididymo-orchitis is not uncommon. Excision of prostatic utricle is the treatment of choice. The various techniques described in literature suffer from the disadvantages of incomplete excision due to poor view.
Jiwane Ashish +3 more
doaj
Frontiers in Neurology, 2018 Background: Cervical VEMPs and ocular VEMPs are tests for evaluating otolith function in clinical practice. We developed a simple, portable and affordable device to record VEMP responses on patients, named μVEMP.
Hamish G. MacDougall +4 more
doaj +1 more source
Cell-type identity of the avian utricle
Cell Reports, 2021 The avian utricle, a vestibular organ of the inner ear, displays turnover of sensory hair cells throughout life. This is in sharp contrast to the mammalian utricle, which shows limited regenerative capacity. Here, we use single-cell RNA sequencing to identify distinct marker genes for the different sensory hair cell subtypes of the chicken utricle ...
Mirko Scheibinger +5 more
openaire +2 more sources
Advances in GPCRs Associated With Wnt Signaling Within the Auditory System
Medicine Bulletin, EarlyView.ABSTRACT G protein‐coupled receptors (GPCRs) that interact with the Wnt signaling pathway are pivotal for auditory system homeostasis, as they orchestrate inner ear development, hair cell (HC) regeneration, and hearing preservation. Frizzled (FZD) receptors, the core Wnt‐related GPCRs, bind Wnt ligands and co‐receptors (e.g., LRP5/6) to activate both ...
Liang Wang +3 more
wiley +1 more source
Disrupted Vestibular Nuclei Neuron Development in a Chick Model for Congenital Vestibular Disorders
Developmental Neurobiology, Volume 86, Issue 3, July 2026.ABSTRACT Children with syndromic, congenital vestibular disorders (CVDs) form a sac‐like inner ear with missing or truncated semicircular canals and experience delayed motor development with lifelong challenges to maintain posture and balance. How the abnormal inner ear affects downstream central vestibular neural circuitry has not been investigated ...
Elizabeth B. Bogin +5 more
wiley +1 more source
Toxic Effects of 3,3′-Iminodipropionitrile on Vestibular System in Adult C57BL/6J Mice In Vivo
Neural Plasticity, 2020 The utricle is one of the five sensory organs in the mammalian vestibular system, and while the utricle has a limited ability to repair itself, this is not sufficient for the recovery of vestibular function after hair cell (HC) loss induced by ototoxic ...
Shan Zeng +13 more
doaj +1 more source
Supporting cells remove and replace sensory receptor hair cells in a balance organ of adult mice
eLife, 2017 Vestibular hair cells in the inner ear encode head movements and mediate the sense of balance. These cells undergo cell death and replacement (turnover) throughout life in non-mammalian vertebrates.
Stephanie A Bucks +5 more
doaj +1 more source