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Mohl's “Primordial Utricle” [PDF]
I SHOULD like to inquire, through the medium of NATURE, whether the way in which botanists now use Mohl's term “primordial utricle” is strictly accurate? In Sachs' “Lehrbuch,” and in the English translation, it is applied to the parietal layer of protoplasm found in plant cells which are old enough to have a large central vacuole, and this practice is ...
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Monosynaptic targets of utricular afferents in the larval zebrafish
The larval zebrafish acquires a repertoire of vestibular-driven behaviors that aid survival early in development. These behaviors rely mostly on the utricular otolith, which senses inertial (tilt and translational) head movements.
Yizhen Jia, Martha W. Bagnall
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ObjectiveThis study aims to investigate the potential vestibular pathway impairment through vestibular evoked myogenic potentials (VEMPs) and to explore the pathophysiological significance of these instrument-based findings in children with recurrent ...
Xiayu Sun +33 more
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Synaptopathy as a Mechanism for Age-Related Vestibular Dysfunction in Mice
Age-related decline of inner ear function contributes to both hearing loss and balance disorders, which lead to impaired quality of life and falls that can result in injury and even death.
Guoqiang Wan +7 more
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Multiscale modeling of mechanotransduction in the utricle [PDF]
We review recent progress in using numerical models to relate utricular hair bundle and otoconial membrane (OM) structure to the functional requirements imposed by natural behavior in turtles. The head movements section reviews the evolution of experimental attempts to understand vestibular system function with emphasis on turtles, including data ...
Jong-Hoon, Nam +3 more
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Transcription factor Emx2 controls stereociliary bundle orientation of sensory hair cells
The asymmetric location of stereociliary bundle (hair bundle) on the apical surface of mechanosensory hair cells (HCs) dictates the direction in which a given HC can respond to cues such as sound, head movements, and water pressure.
Tao Jiang, Katie Kindt, Doris K Wu
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The segregation of Calb1, Calb2, and Prph neurons reveals distinct and mixed neuronal populations and projections to hair cells in the inner ear and central nuclei. [PDF]
Three populations of hair cells have a distinct expression of Calb1 and Calb2. (A, A′D) The central is highly positive for Calb1 while surrounding HC are positive for Calb2. Later, a calyx forms primarily with Calb1. (B, B′, D′, D″) Saccule and utricle start out positive for Calb2 but will upregulate the Calb1 in the striola that is primarily forming ...
Lee JH +6 more
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Age-dependent structural reorganization of utricular ribbon synapses
In mammals, spatial orientation is synaptically-encoded by sensory hair cells of the vestibular labyrinth. Vestibular hair cells (VHCs) harbor synaptic ribbons at their presynaptic active zones (AZs), which play a critical role in molecular scaffolding ...
Susann Michanski +28 more
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Excision of Prostatic Utricle: When? How?
The prostatic utricle is a rare anomaly in the urogenital system and is generally thought to develop from remnants of the Müllerian duct. Prostatic utricle is usually accompanied by hypospadias, renal agenesis, and cryptorchidism, and it is mostly ...
Gökhan Karakurt +3 more
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Hair cell damage recruited Lgr5-expressing cells are hair cell progenitors in neonatal mouse utricle
Damage-activated stem/progenitor cells play important roles in regenerating lost cells and in tissue repair. Previous studies reported that the mouse utricle has limited hair cell regeneration ability after hair cell ablation.
Jinchao eLin +3 more
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