HSV-1 not only in human vestibular ganglia but also in the vestibular labyrinth [PDF]
, 2001 Reactivation of herpes simplex virus type 1 (HSV-1) in the vestibular ganglion (VG) is the suspected cause of vestibular neuritis (VN). Recent studies reported the presence of HSV-1 DNA not only in human VGs but also in vestibular nuclei, a finding that ...
Arbusow, Viktor +4 more
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Synaptopathy as a Mechanism for Age-Related Vestibular Dysfunction in Mice
Frontiers in Aging Neuroscience, 2019 Age-related decline of inner ear function contributes to both hearing loss and balance disorders, which lead to impaired quality of life and falls that can result in injury and even death.
Guoqiang Wan +7 more
doaj +1 more source
Mohl's “Primordial Utricle” [PDF]
Nature, 1894 I SHOULD like to inquire, through the medium of NATURE, whether the way in which botanists now use Mohl's term “primordial utricle” is strictly accurate? In Sachs' “Lehrbuch,” and in the English translation, it is applied to the parietal layer of protoplasm found in plant cells which are old enough to have a large central vacuole, and this practice is ...
openaire +1 more source
Transcription factor Emx2 controls stereociliary bundle orientation of sensory hair cells
eLife, 2017 The asymmetric location of stereociliary bundle (hair bundle) on the apical surface of mechanosensory hair cells (HCs) dictates the direction in which a given HC can respond to cues such as sound, head movements, and water pressure.
Tao Jiang, Katie Kindt, Doris K Wu
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The tip-link antigen, a protein associated with the transduction complex of sensory hair cells, is protocadherin-15 [PDF]
, 2006 Sound and acceleration are detected by hair bundles, mechanosensory structures located at the apical pole of hair cells in the inner ear. The different elements of the hair bundle, the stereocilia and a kinocilium, are interconnected by a variety of link
Ahmed, Zubair M +14 more
core +2 more sources
Age-dependent structural reorganization of utricular ribbon synapses
Frontiers in Cell and Developmental Biology, 2023 In mammals, spatial orientation is synaptically-encoded by sensory hair cells of the vestibular labyrinth. Vestibular hair cells (VHCs) harbor synaptic ribbons at their presynaptic active zones (AZs), which play a critical role in molecular scaffolding ...
Susann Michanski +28 more
doaj +1 more source
Bladder Outlet Obstruction Secondary to a Prostatic Cyst in a Young Adult: A Rare Case Report. [PDF]
Clin Case RepABSTRACT Bladder outlet obstruction secondary to an obstructing prostatic cyst is a rare clinical entity. Incomplete regression of the Müllerian duct is supposed to be the cause of such cysts. Clinical features can range from acute bladder outlet obstruction to chronic urinary retention, oligospermia, and prostatitis‐like symptoms.
K C S +3 more
europepmc +2 more sources
Defective Tmprss3-Associated Hair Cell Degeneration in Inner Ear Organoids [PDF]
, 2019 Mutations in the gene encoding the type II transmembrane protease 3 (TMPRSS3) cause human hearing loss, although the underlying mechanisms that result in TMPRSS3-related hearing loss are still unclear.
Alex, Alpha L. +8 more
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Co-transduction of dual-adeno-associated virus vectors in the neonatal and adult mouse utricles
Frontiers in Molecular Neuroscience, 2022 Adeno-associated virus (AAV)-mediated gene transfer is an efficient method of gene over-expression in the vestibular end organs. However, AAV has limited usefulness for delivering a large gene, or multiple genes, due to its small packaging capacity (<
Zhong-Rui Chen +19 more
doaj +1 more source