Results 31 to 40 of about 87,820 (142)

Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma

Advanced Science, EarlyView.
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert, Christophe Nguyen, Sean Edward Dunn, Magali Gary‐Bobo, Jérôme Lacombe, Justin Moser, Frédéric Zenhausern, Jean‐Olivier Durand, Frédérique Cunin   +8 more
wiley   +1 more source

SOX10 Expression as Well as BRAF and GNAQ/11 Mutations Distinguish Pigmented Ciliary Epithelium Neoplasms From Uveal Melanomas

Investigative Opthalmology & Visual Science, 2017
Adenocarcinomas or adenomas derived from pigmented ciliary epithelium (APCE) are exceptionally rare ocular tumors. These tumors have pigmented and epithelioid features, and some APCEs are negative for keratin markers and positive for melanocytic markers. It is especially difficult to distinguish APCEs from uveal melanoma (UM).
Taisuke, Mori, Aoi, Sukeda, Shigeki, Sekine, Shinsuke, Shibata, Eijitsu, Ryo, Hideyuki, Okano, Shigenobu, Suzuki, Nobuyoshi, Hiraoka   +7 more
openaire   +2 more sources

Cytogenetic analysis of uveal melanomas: a long-term experience [PDF]

, 2013
Background/aim: Cytogenetic profile of posterior uveal melanoma (mainly monosomy 3) is actually considered the most specific prognostic factor for uveal melanoma patients.
Parrozzani, Raffaele
core  

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

Uveitis Masquerade Syndrome

Ukrainian Journal of Ophthalmology
The ‘uveitis masquerade syndrome’ is a large group of neoplastic and non-neoplastic conditions that mimic and are initially misdiagnosed as uveitis.
M. K. Shields, L. B. Ferreira, A. L. Farrall, J. R. Smith   +3 more
doaj   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Artificial Intelligence in Ophthalmology: From Methodological Advances to Clinical Translation and Future Directions

Eye &ENT Research, EarlyView.
ABSTRACT Artificial intelligence (AI) is reshaping ophthalmology from task‐specific image analysis toward multimodal, longitudinal, and clinically integrated decision support. This narrative review summarizes the methodological evolution of ophthalmic AI, including traditional machine learning, task‐specific deep learning, self‐supervised learning ...
Yuxin Liu, Hanruo Liu
wiley   +1 more source

Assessment of the survival rate of patients with malignant neoplasms of the choroid in the Orenburg region

Российский офтальмологический журнал
The purpose of the work is to analyze the impact of various factors on the survival of patients with malignant neoplasms of the choroid.Materials and methods. A retrospective analysis of the databases of the V.I.
A. E. Aprelev, D. N. Begun, I. I. Zakirova, S. A. Shmitkova   +3 more
doaj   +1 more source

Evidências obtidas de um caso de melanoma de íris recidivado Evidences from a case of recurrent iris melanoma

Revista Brasileira de Oftalmologia, 2009
O artigo apresenta uma análise histológica de um caso de melanoma recidivado de íris após sete meses da iridociclectomia, em uma paciente de 45 anos.
Juliana de Lucena Martins Ferreira, Márjorie Sabino Façanha Barreto Rolim, Cícero Narciso Moreira Leite, Fernando Queiroz Monte, Marineuza Rocha Memória   +4 more
doaj   +1 more source

Stereotactic Radiotherapy in Uveal Melanoma

, 2014
Uveal melanoma is the most common primary malignant intraocular neoplasm in adults. The aims of treatment of the uveal melanoma are to prevent the metastatic spread of the disease and to preserve as much useful vision as possible.
Ela Delikgöz Soykut, Yıldız Yükselen Güney, Ayşen Dizman   +2 more
core   +1 more source