Results 21 to 30 of about 87,820 (142)
Mixed-Cell Type Choroidal Melanoma in a Middle-Aged Woman
Introduction: Melanomas are malignant neoplasms that occur in various anatomical sites, including the eye. Ocular melanomas account for 5% of all melanomas and are mainly described in Caucasian and older individuals.
Mirelly Aparecida Nolasco Frinhani +8 more
doaj +1 more source
Proton beam radiotherapy in the management of uveal melanoma: clinical experience in Scotland [PDF]
<p>Aim: To evaluate proton-beam radiotherapy (PBRT) in the management of uveal melanoma in Scotland.</p> <p>Methods: A retrospective review was undertaken on all patients receiving PBRT for uveal melanoma (1994–2005).
McConnachie, A. +9 more
core +1 more source
Epigenetic Activation of SOX11 in Lymphoid Neoplasms by Histone Modifications [PDF]
Recent studies have shown aberrant expression of SOX11 in various types of aggressive B-cell neoplasms. To elucidate the molecular mechanisms leading to such deregulation, we performed a comprehensive SOX11 gene expression and epigenetic study in stem ...
Amador Virginia +107 more
core +1 more source
Chromosomal Gains and Losses in Uveal Melanomas Detected by Comparative Genomic Hybridization [PDF]
Eleven uveal melanomas were analyzed using comparative genomic hybridization (CGH). The most abundant genetic changes were loss of chromosome 3, overrepresentation of 6p, loss of 6q, and multiplication of 8q.
Speicher, Michael R. +7 more
core +1 more source
Intraocular Medulloepitheliomae (Clinical Case Series)
Purpose. Retrospective analysis of clinical, instrumental, cytological and pathological features of intraocular medulloepithelioma based on our own experience in the period from 2005 to 2018. Patients and Methods.
S. V. Saakyan +7 more
doaj +1 more source
Gnaq and Gna11 in the Endothelin signaling pathway and melanoma
In this article, we first briefly outline the function of G protein coupled receptors in cancer, and then specifically examine the roles of the seven transmembrane G protein coupled Endothelin B receptor (Ednrb) and the G proteins, GNAQ and GNA11, in ...
Oscar eUrtatiz +1 more
doaj +1 more source
Amelanotic ocular melanoma with lung metastasis in a domestic rabbit (Oryctolagus cuniculus) [PDF]
: Uterine adenocarcinoma and lymphoma are among the most diagnosed neoplasms in rabbits. Melanomas have also been reported in rabbits; however, they occur less frequently.
Ronaldo José Piccoli +8 more
doaj +1 more source
Instability of microsatellites is an infrequent event in uveal melanoma
Microsatellite instability (MSI) is a distinct tumour phenotype that is associated with alterations of DNA mismatch repair and is being increasingly reported in a number of hereditary and sporadic tumours. Numerous reports have suggested that melanocytic
Murray, Anna K +4 more
core +6 more sources
BAP1 cancer syndrome: malignant mesothelioma, uveal and cutaneous melanoma, and MBAITs
Background BRCA1–associated protein 1 (BAP1) is a tumor suppressor gene located on chromosome 3p21. Germline BAP1 mutations have been recently associated with an increased risk of malignant mesothelioma, atypical melanocytic tumors and other neoplasms ...
Carbone Michele +15 more
doaj +1 more source
Abstract Background Uveal Melanoma (UVM) is the most common ocular malignancy. Many mutations were identified in affected patients defining genetic predisposition syndromes. Previous studies discussed separately the incidence of single or second primary ocular melanomas.
A.S. Alfaar, A.M. Saad, S. Elzouki
openaire +1 more source

