Results 1 to 10 of about 87,820 (142)

SF3B1 and EIF1AX mutations occur in primary leptomeningeal melanocytic neoplasms; yet another similarity to uveal melanomas [PDF]

Acta Neuropathologica Communications, 2016
Like uveal melanomas, primary leptomeningeal melanocytic neoplasms (LMNs) frequently carry GNAQ and GNA11 mutations. However, it is currently unknown whether these LMNs harbor mutations in BAP1, SF3B1 and/or EIF1AX like uveal melanomas as well. In this study, we used Sanger sequencing for the detection of mutations in SF3B1 (hotspots in exon 14 and 15)
Küsters-Vandeveld, Heidi VN, Creytens, David, van Engen- van Grunsven, Adriana CH, Jeunink, Marcel, Winnepenninckx, Veronique, Groenen, Patricia JTA, Küsters, Benno, Wesseling, Pieter, Blokx, Willeke AM, Prinsen, Clemens FM   +9 more
core   +11 more sources

BILATERAL DIFFUSE MELANOCYTIC UVEAL TUMOURS ASSOCIATED WITH SYSTEMIC MALIGNANT NEOPLASM [PDF]

Australian and New Zealand Journal of Ophthalmology, 1986
AbstractA case of bilateral diffuse melanocytic uveal tumours /n a 34‐year‐old male in association with a systemic carcinoma is described clinically, by light microscopy and by transmission electron microscopy Although the reports of such cases are extremely rare, they do not necessarily represent a new syndrome.
M, Filipic, J S, Ambler
openaire   +2 more sources

Retrospective analysis of secondary enucleation for uveal melanoma after plaque radiotherapy

BMC Ophthalmology, 2022
Background Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. Plaque brachytherapy (PRT) is widely accepted as an effective globe-conserving treatment modality for UM.
Heng Wang, Ruiheng Zhang, Yining Wang, Rongtian Chen, Yueming Liu, Yang Li, Wenbin Wei   +6 more
doaj   +1 more source

Anterior uveal neurilemmoma--a rare neoplasm simulating malignant melanoma. [PDF]

British Journal of Ophthalmology, 1987
A 30-year-old woman presented with dilated episcleral vessels in the right eye which were found to be associated with an underlying ciliary body tumour. Contact lens examination, transpupillary transillumination, ultrasonography, computerised tomography, magnetic resonance imaging, and fine needle aspiration biopsy produced apparently conflicting and ...
P A, Smith, B E, Damato, M K, Ko, R W, Lyness   +3 more
openaire   +2 more sources

Systemic anti-CD20 (rituximab) as primary treatment for symptomatic primary uveal lymphoma

American Journal of Ophthalmology Case Reports, 2019
Purpose: Uveal lymphomas are indolent, frequently choroid-involving neoplasms that are mainly CD20-positive B-cell extranodal marginal zone lymphoma. Irreversible visual loss may occur from retinal detachment and/or glaucoma among untreated symptomatic ...
Honeylen Maryl Tiu Teo, Süleyman Çiftçi, Victor Maurice Elner, Hakan Demirci   +3 more
doaj   +1 more source

Malignant melanotic nerve sheath tumor with PRKAR1A, KMT2C and GNAQ mutations

Free Neuropathology, 2022
Malignant melanotic nerve sheath tumor (MMNST) is a rare and potentially aggressive lesion defined in the 2021 WHO Classification of Tumors of the Central Nervous System.
Merryl Terry, Kristina Wakeman, Brian Williams, Donald Miller, Müge Sak, Zied Abdullaev, Marwil Pacheco, Kenneth Aldape, Norman Lehman   +8 more
doaj   +1 more source

Immunoexpression of Macroh2a in Uveal Melanoma

Applied Sciences, 2019
MacroH2A is a histone variant whose expression has been studied in several neoplasms, including cutaneous melanomas (CMs). In the literature, it has been demonstrated that macroH2A.1 levels gradually decrease during CM progression, and a high expression ...
Lucia Salvatorelli, Lidia Puzzo, Giovanni Bartoloni, Stefano Palmucci, Antonio Longo, Andrea Russo, Michele Reibaldi, Manlio Vinciguerra, Giovanni Li Volti, Rosario Caltabiano   +9 more
doaj   +1 more source

Uveal metastasis arising from thyroid neoplasms: a systemic review of case reports

, 2023
Abstract Purpose: We systematically reviewed the case report literature to identify cases of uveal metastases (UM) originating from Thyroid Cancers (TCs) and evaluate this condition's demographic, ophthalmologic, and oncologic characteristics.
Mirsaeed Abdollahi, Hooman Nateghian, Navid Sobhi, Ali Jafarizadeh   +3 more
openaire   +1 more source

Management of primary choroidal lymphoma presenting as extensive serous retinal detachment and salmon patch of bulbar conjunctiva: a case report

Journal of Medical Case Reports, 2022
Background We describe the outcome of ultra-low-dose radiotherapy plus intravitreal methotrexate and rituximab injections for a patient with primary choroidal lymphoma who presented with nodular conjunctival salmon patches and extensive serous retinal ...
Zahra Mahdizad, Elias Khalili Pour, Mohammadreza Mehrabi Bahar, Amirreza Esfandiari, Babak Masoomian, Hamid Riazi-Esfahani, Ahmad Mirshahi, Fariba Ghassemi   +7 more
doaj   +1 more source

ANALYSIS OF THE PREVALENCE OF METASTATIC CHOROIDAL LESIONS

Alʹmanah Kliničeskoj Mediciny, 2017
Background: Ophthalmologists have a  low oncological vigilance, while oncologists are insufficiently aware of the incidence of choroidal metastases.
Ya. V. Parmon, S. V. Saakyan
doaj   +1 more source