Results 71 to 80 of about 356,274 (192)

Mucosal Melanoma of Head and Neck: A Rare and Aggressive Disease—A Register‐Based Cohort Study

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Mucosal melanomas of the head and neck are rare and often diagnosed in the advanced stage. This study examines the incidence, survival and histology of mucosal melanoma compared to its cutaneous counterpart. Methods This register‐based cohort study reviews head and neck melanomas at Helsinki University Hospital, Finland, from 2002 ...
Sara C. Degerholm, Tuula A. Salo, Matti O. Mauramo   +2 more
wiley   +1 more source

Epidemiology of Four Major Canine Tumours in the UK: Insights From a National Pathology Registry With Comparative Oncology Perspectives

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Pet dogs with naturally occurring cancers provide valuable models for comparative oncology and pathology tumour registries offer a powerful resource for onco‐epidemiological research. Here, we analysed the Small Animal Veterinary Surveillance Network (SAVSNET) pathology‐based tumour registry (PTR), one of the largest veterinary tumour ...
José Rodríguez, Antonio Espinosa de los Monteros, Ángelo Santana, P. J. Noble, Alan D. Radford, Francesco Cian, Annika Herrmann, Jenny S. McKay, Matthew Jones, David R. Killick   +9 more
wiley   +1 more source

Clinical descriptive and long‐term outcome of melanocytic uveal lesions in young dogs: 40 cases (45 eyes) including 13 cases of sector iridectomy

Veterinary Ophthalmology, Volume 28, Issue 2, Page 371-385, March 2025.
Abstract Purpose To describe the clinical features surgical technique, early and long‐term outcome with or without surgery, and histopathological findings of melanocytic anterior uveal lesions in young dogs. Methods Medical records of dogs at a guide dog facility removed from training due to a pigmented iris lesion were reviewed from 2014 to 2021 ...
Valerie Liliane Dufour, Julie A. Cohen, Charles‐Antoine Assenmacher, Dolores M. Holle, Amy C. Durham, Gustavo D. Aguirre, Keiko Miyadera   +6 more
wiley   +1 more source

Parthenolide Attenuates Skeletal Muscle Atrophy Through Regulation of Protein Homeostasis and Inhibition of Inflammation

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Parthenolide attenuates skeletal muscle atrophy through coordinated regulation of protein homeostasis and inflammatory signaling. It counteracts TNF‐α‐mediated inhibition of AKT signaling, thereby restoring AKT–mTOR activation to promote protein synthesis and suppress protein degradation through inhibition of the FoxO transcription factors, which ...
Yu Bai, Weiqing Li, Yahong Lu, Hehuan Lai, Lin Ye, Kechi Li, Chendi Wang, Yi Ding, Wenhao Li, Yitao Chen, Keping Gan, Zhenzhong Chen, Dengwei He   +12 more
wiley   +1 more source

Quercetin and Its Nano‐Based Formulations Against Skin Cancer: A Narrative Review

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Skin cancer is one of the most prevalent malignancies worldwide, characterized by the abnormal growth of skin cells and significant clinical challenges. Conventional treatments—including surgery, chemotherapy, and radiotherapy—often suffer from limitations such as adverse side effects, tumor resistance, and inadequate efficacy.
Mahtab Khanyabzadeh, Alireza Emamifar, Nikoo Emtiazi, Amir Nazari, Masoumeh Shekarriz, Amin Karami, Fateme Hashem Beik Mahallati, Rahineh Nomani Lafmejani, Atieh Dariush, Seyed Mohammad Mahdi Rohani, Elaheh Mohseni Vadeghani, Negin Khoshnood, Hamid Reza Ojaghi, Fatemeh Rezaei‐Tazangi, Reza Arefnezhad   +14 more
wiley   +1 more source

An Updated Narrative Review on the Therapeutic Potential of Resveratrol in the Treatment of Cancer

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Cancer is a significant global health challenge, affecting millions of people every year. Overall survival rates have improved over time, but some patients exhibit treatment resistance, prompting ongoing research to find suitable and effective sensitizers.
Mohammad Ashraful Islam, Al Amin, Md. Abdul Aziz, Md. Mahabubur Rahaman, Jakir Hossain, Jakir Ahmed Chowdhury, Mohammad Safiqul Islam   +6 more
wiley   +1 more source

Varicella Zoster Virus Infection: Clinical Features, Molecular Pathogenesis, Treatment, and Prevention

MedComm, Volume 7, Issue 3, March 2026.
This review focuses on the clinical features, molecular mechanisms, treatment methods, and preventive measures of the VZV, with the aim of providing a theoretical basis for the development of new treatment and prevention methods for HZ. ABSTRACT Varicella zoster virus (VZV) is a ubiquitous human herpesvirus that establishes lifelong latency and causes ...
Lei Peng, Honghao Song, Tianying Li, Yuqing Ma, Chen Yan, Yuhan Cao, Kaiqiang Sun, Chaofeng Han, Hongbin Yuan   +8 more
wiley   +1 more source

Plaque‐adaptive flexible film dosimetry system for Ru‐106 plaque brachytherapy commissioning and quality assurance

Medical Physics, Volume 53, Issue 3, March 2026.
Abstract Background Ruthenium‐106 (Ru‐106) plaque brachytherapy is an established treatment modality for choroidal melanoma that delivers localized beta radiation while sparing surrounding ocular structures. It is widely used in Europe and parts of Asia, whereas COMS Iodine‐125 and Palladium‐103 plaques remain the standard in the United States. However,
Jin Dong Cho, Hojae Kim, Dong Wook Kim, Heerim Nam, Jin Sung Kim, Jung‐in Kim   +5 more
wiley   +1 more source

The Eye Never Lies: When A Lesion Unveils Lung Cancer

Respirology Case Reports, Volume 14, Issue 3, March 2026.
We present a rare case of asymptomatic primary lung adenocarcinoma that first manifested with ocular symptoms and an iris lesion. ABSTRACT Ocular manifestations rarely represent the first sign of systemic malignancy and often pose a diagnostic challenge. While choroidal metastases are more common, iris involvement is uncommon and may be underrecognized.
Sivanesan Darshini, Nor Safiqah Sharil, Boon Hau Ng, Xin Yee Chong, Andrea Yu‐Lin Ban, Nik Nuratiqah Nik Abeed   +5 more
wiley   +1 more source

Novel Combined Approach for Vision‐Preserving Iridociliary Tumour Excision in a Small‐Breed Dog: Contralateral Iris Excision With En‐Bloc Scleral Resection

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
• A 2.8 mm corneal paracentesis positioned opposite to the tumour location enabled fine iris scissors insertion for precise excision of tumour‐bearing iris tissue under miotic guidance with pilocarpine 2%. • A fornix‐based conjunctival peritomy 5 mm from the limbus and stepped scleral flap approach allowed circumferential deep scleral incision with 2–3 
Jae‐Ik Kang, Jeong‐Eun Yeom, Kyung‐Mee Park   +2 more
wiley   +1 more source