Results 11 to 20 of about 10,440,305 (287)
Frontiers in Plant Science, 2022 V-ATPase is the dominant proton pump in plant cells. It contributes to cytosolic pH homeostasis and energizes transport processes across endomembranes of the secretory pathway.
Thorsten Seidel
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Reciprocal Regulation of V-ATPase and Glycolytic Pathway Elements in Health and Disease [PDF]
Frontiers in Physiology, 2019 The ability of cells to adapt to fluctuations in glucose availability is crucial for their survival and involves the vacuolar proton-translocating ATPase (V-ATPase), a proton pump found in all eukaryotes.
Summer R. Hayek +2 more
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V-ATPase Dysfunction in the Brain: Genetic Insights and Therapeutic Opportunities
CellsVacuolar-type ATPase (v-ATPase) is a multimeric protein complex that regulates H+ transport across membranes and intra-cellular organelle acidification. Catabolic processes, such as endocytic degradation and autophagy, strictly rely on v-ATPase-dependent
Antonio Falace +5 more
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Yeast TLDc domain proteins regulate assembly state and subcellular localization of the V-ATPase [PDF]
The EMBO JournalYeast vacuoles perform crucial cellular functions as acidic degradative organelles, storage compartments, and signaling hubs. These functions are mediated by important protein complexes, including the vacuolar-type H+-ATPase (V-ATPase), responsible for ...
Samira Klössel +6 more
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Cryo-EM structures of intact V-ATPase from bovine brain
Nature Communications, 2020 The vacuolar-type H+ -ATPases (V-ATPase) hydrolyze ATP to pump protons across the plasma or intracellular membrane. Here authors report two cryo-EM structures of the intact V-ATPase from bovine brain with all the subunits including the subunit H, which ...
Rong Wang +6 more
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Molecular mechanism of Oxr1p mediated disassembly of yeast V-ATPase
EMBO ReportsThe eukaryotic vacuolar H+-ATPase (V-ATPase) is regulated by reversible disassembly into autoinhibited V1-ATPase and Vo proton channel subcomplexes. We recently reported that the TLDc protein Oxr1p induces V-ATPase disassembly in vitro.
Md. Murad Khan, Stephan Wilkens
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Targeting the NR1D1-IGF2BP2-V-ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis-Induced Immunosuppression. [PDF]
Adv Sci (Weinh)Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Chen L +13 more
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The Function of V-ATPases in Cancer [PDF]
Physiological Reviews, 2016 The vacuolar ATPases (V-ATPases) are a family of proton pumps that couple ATP hydrolysis to proton transport into intracellular compartments and across the plasma membrane. They function in a wide array of normal cellular processes, including membrane traffic, protein processing and degradation, and the coupled transport of small molecules, as well as ...
Laura, Stransky +2 more
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Duelling functions of the V‐ATPase [PDF]
The EMBO Journal, 2011 The V‐ATPase, the major cellular proton pump, is comprised of the peripheral sector V1 catalysing ATP hydrolysis and the membrane integral sector V0 translocating protons. Ten years ago, Andreas Mayer9s group made the surprising observation that proteolipids of the V0 transmembrane sector are implicated in membrane fusion, but deeper analysis proved to
Scott Cameron C +2 more
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Development of RNAi methods for Peregrinus maidis, the corn planthopper. [PDF]
PLoS ONE, 2013 The corn planthopper, Peregrinus maidis, is a major pest of agronomically-important crops. Peregrinus maidis has a large geographical distribution and transmits Maize mosaic rhabdovirus (MMV) and Maize stripe tenuivirus (MSpV).
Jianxiu Yao +4 more
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