Regulation of vacuolar H+-ATPase activity by the Cdc42 effector Ste20 in Saccharomyces cerevisiae [PDF]
In the budding yeast Saccharomyces cerevisiae, the Cdc42 effector Ste20 plays a crucial role in the regulation of filamentous growth, a response to nutrient limitation.
Höfken, T, Lin, M, Kane, PM, Li, SC
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Regulation of TFEB and V‐ATPases by mTORC1 [PDF]
Mammalian target of rapamycin (mTOR) complex 1 (mTORC1) is an important, highly conserved, regulator of cell growth. Ancient among the signals that regulate mTORC1 are nutrients. Amino acids direct mTORC1 to the surface of the late endosome/lysosome, where mTORC1 becomes receptive to other inputs.
Peña-Llopis, Samuel +8 more
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Subcellular distribution of the V-ATPase complex in plant cells, and in vivo localisation of the 100 kDa subunit VHA-a within the complex [PDF]
Kluge C, Seidel T, Bolte S, et al. Subcellular distribution of the V-ATPase complex in plant cells, and in vivo localisation of the 100 kDa subunit VHA-a within the complex. BMC Cell Biology. 2004;5(1):29.Background: Vacuolar H+-ATPases are large protein
Thorsten Seidel +35 more
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Background Lysosomes digest extracellular material from the endocytic pathway and intracellular material from the autophagic pathway. This process is performed by the resident hydrolytic enzymes activated by the highly acidic pH within the lysosomal ...
Qiaoyun Song +3 more
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The evolutionary conserved TLDc domain defines a new class of (H+)V-ATPase interacting proteins
We recently found that nuclear receptor coactivator 7 (Ncoa7) and Oxr1 interact with the proton-pumping V-ATPase. Ncoa7 and Oxr1 belong to a group of proteins playing a role in the oxidative stress response, that contain the conserved “TLDc” domain. Here
A. F. Eaton, D. Brown, M. Merkulova
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Organelle-specific isoenzymes of plant V-ATPase as revealed by in vivo-FRET analysis [PDF]
Seidel T, Schnitzer D, Golldack D, Sauer M, Dietz K-J. Organelle-specific isoenzymes of plant V-ATPase as revealed by in vivo-FRET analysis. BMC Cell Biology. 2008;9(1): 28.BACKGROUND: The V-ATPase (VHA) is a protein complex of 13 different VHA-subunits.
Thorsten Seidel +14 more
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Wheat V-H+-ATPase subunit genes significantly affect salt tolerance in Arabidopsis thaliana. [PDF]
Genes for V-H(+)-ATPase subunits were identified and cloned from the salt-tolerant wheat mutant RH8706-49. Sequences of these genes are highly conserved in plants.
Xiaoliang He +3 more
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SNARE, V-ATPase et neurotransmission [PDF]
> La communication entre neurones repose principalement sur les synapses chimiques et par consequent sur la liberation de neurotransmetteurs. Au niveau des terminaisons nerveuses, des vesicules synaptiques remplies de neurotransmetteurs s’arriment a la membrane plasmique et subissent des etapes de maturation qui les rendent competentes pour la fusion ...
El Far, Oussama, Seagar, Michael
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Modulation of the Actin Cytoskeleton via Gelsolin Regulates Vacuolar H+-ATPase Recycling [PDF]
The role of the actin cytoskeleton in regulating membrane protein trafficking is complex and depends on the cell type and protein being examined. Using the epididymis as a model system in which luminal acidification is crucial for sperm maturation and ...
Pastor-Soler, Nuria +8 more
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Decreased expression of V-ATPase upon the siRNA transfection.
The 5637 BECs transfected with NS siRNA or V-ATPase siRNA (25, 50, or 100 pmol) and immunoblotted using an anti-V-ATPase antibody to examine the expression of V-ATPase. Anti-β-actin antibody was used for a loading control. (TIF)
Hae Woong Choi (6522491) +12 more
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