Results 91 to 100 of about 9,622 (181)

Unleashing the Antiviral Potential of Stapled Peptides: A New Frontier in Combating Human Neurotropic Viral Infections

Microbial Biotechnology, Volume 18, Issue 9, September 2025.
Human neurotropic viruses like SARS‐CoV‐2, HSV, HOPV and RSV pose significant risks due to their ability to invade and persist in the nervous system. Stapled peptides represent a promising therapeutic approach with enhanced stability, target affinity and bioavailability, emerging as an effective strategy for neutralising human neurotropic viruses ...
Sanskruti Patil, Rakesh Rahangdale, Mukesh Pasupuleti, Puttur Santhoshkumar, Raghu Chandrashekar Hariharapura   +4 more
wiley   +1 more source

Attaining the Balance between Wild Poliovirus Eradication and Vaccine-Derived Poliovirus Control [PDF]

Journal of Infectious Diseases and Epidemiology, 2021
Emmanuel Ebuka Elebesunu, Confidence Nmesoma Ubani   +1 more
openaire   +1 more source

Wild and vaccine-derived poliovirus circulation, and implications for polio eradication [PDF]

Epidemiology and Infection, 2016
SUMMARYPolio cases due to wild virus are reported by only three countries in the world. Poliovirus type 2 has been globally eradicated and the last detection of poliovirus type 3 dates to November 2012. Poliovirus type 1 remains the only circulating wild strain; between January and September 2016 it caused 26 cases (nine in Afghanistan, 14 in Pakistan,
openaire   +4 more sources

Immunogenicity and safety evaluation of bivalent types 1 and 3 oral poliovirus vaccine by comparing different poliomyelitis vaccination schedules in China: A randomized controlled non-inferiority clinical trial

Human Vaccines & Immunotherapeutics, 2017
Background: The type 2 component of the oral poliovirus vaccine is targeted for global withdrawal through a switch from the trivalent oral poliovirus vaccine (tOPV) to a bivalent oral poliovirus vaccine (bOPV). The switch is intended to prevent paralytic
Jingjun Qiu, Yunkai Yang, Lirong Huang, Ling Wang, Zhiwei Jiang, Jian Gong, Wei Wang, Hongyan Wang, Shaohong Guo, Chanjuan Li, Shuyuan Wei, Zhaojun Mo, Jielai Xia   +12 more
doaj   +1 more source

Twenty-Eight Years of Poliovirus Replication in an Immunodeficient Individual: Impact on the Global Polio Eradication Initiative.

PLoS Pathogens, 2015
There are currently huge efforts by the World Health Organization and partners to complete global polio eradication. With the significant decline in poliomyelitis cases due to wild poliovirus in recent years, rare cases related to the use of live ...
Glynis Dunn, Dimitra Klapsa, Thomas Wilton, Lindsay Stone, Philip D Minor, Javier Martin   +5 more
doaj   +1 more source

Environmental Surveillance of Polioviruses in Armenia, Colombia before Trivalent Oral Polio Vaccine Cessation

Viruses, 2019
Although acute flaccid paralysis (AFP) surveillance is the “gold standard” for detecting cases of polio, environmental surveillance can provide supplementary information in the absence of paralytic poliomyelitis cases.
María Mercedes González, Magile C. Fonseca, Carlos Andrés Rodríguez, Alejandra María Giraldo, José Joaquín Vila, Jhon Carlos Castaño, Leonardo Padilla, Luis Sarmiento   +7 more
doaj   +1 more source

Circulating vaccine derived poliovirus and the polio eradication endgame.

The Pan African medical journal, 2013
No Abstract. Key words: Polio, polio eradication, vaccine derived poliovirus, Oral polio vaccine, inactivated polio vaccine ...
Robert, Davis, Peter F, Wright
openaire   +3 more sources

An outbreak of circulating vaccine derived poliovirus in Yemen, 2011-2012 [PDF]

, 2014
A.A.T. Jaawal
openalex   +1 more source

Monitoring the VDPV2 outbreak in Egypt during 2020–2021 highlights the crucial role of environmental surveillance and boosting immunization in combating Poliovirus

BMC Infectious Diseases
Background Poliovirus is a highly infectious enterovirus (EV) that primarily affects children and can lead to lifelong paralysis or even death. Vaccine-derived polioviruses (VDPVs) are a great threat since they are derived from the attenuated virus in ...
Menna R. Shabana, Amira Y. Zaghloul, Tamer H. El Shaarawy, Nooran S. Elleboudy, Khaled M. Aboshanab   +4 more
doaj   +1 more source

Rare adverse events associated with oral poliovirus vaccine in Brazil

Brazilian Journal of Medical and Biological Research, 1997
Oral poliovirus vaccine (OPV) developed by A. Sabin has been effectively used to control poliomyelitis in Brazil, and the last case with the isolation of a wild poliovirus strain occurred in March 1989.
Friedrich F.
doaj