Results 91 to 100 of about 44,954 (187)

The Pathology of Poliomyelitis and the Vaccines and Nonvaccine Therapy [PDF]

E3S Web of Conferences, 2021
Poliomyelitis is an exclusively human disease that mainly affects children. Clinical features of poliomyelitis can be varied, from mild illness to the most severe paralysis, and the factor why poliomyelitis has different performances in individuals has ...
Chen Yushuo, Yue Tianrui, Zhang Zixiao
doaj   +1 more source

Wild and vaccine-derived poliovirus circulation, and implications for polio eradication [PDF]

Epidemiology and Infection, 2016
SUMMARYPolio cases due to wild virus are reported by only three countries in the world. Poliovirus type 2 has been globally eradicated and the last detection of poliovirus type 3 dates to November 2012. Poliovirus type 1 remains the only circulating wild strain; between January and September 2016 it caused 26 cases (nine in Afghanistan, 14 in Pakistan,
openaire   +4 more sources

Prolonged Replication of a Type 1 Vaccine-Derived Poliovirus in an Immunodeficient Patient [PDF]

Journal of Clinical Microbiology, 1998
ABSTRACT VP1 sequences were determined for poliovirus type 1 isolates obtained over a 189-day period from a poliomyelitis patient with common variable immunodeficiency syndrome (a defect in antibody formation). The isolate from the first sample, taken 11 days after onset of paralysis, contained two poliovirus populations, differing from the ...
Olen M. Kew, Linda Quick, Michael J. McDonough, Roland W. Sutter, D. Rebecca Prevots, Baldev K. Nottay, Mark A. Pallansch   +6 more
openaire   +3 more sources

Estimated Effect of Inactivated Poliovirus Vaccine Campaigns, Nigeria and Pakistan, January 2014–April 2016

Emerging Infectious Diseases, 2017
In 2014, inactivated poliovirus vaccine (IPV) campaigns were implemented in Nigeria and Pakistan after clinical trials showed that IPV boosts intestinal immunity in children previously given oral poliovirus vaccine (OPV). We estimated the effect of these
George Shirreff, Mufti Zubair Wadood, Rui Gama Vaz, Roland W. Sutter, Nicholas C. Grassly   +4 more
doaj   +1 more source

Update on Vaccine-Derived Poliovirus Outbreaks — Worldwide, July 2019–February 2020 [PDF]

MMWR. Morbidity and Mortality Weekly Report, 2020
Circulating vaccine-derived polioviruses (cVDPVs) can emerge in areas with low poliovirus immunity and cause outbreaks* of paralytic polio (1-5). Among the three types of wild poliovirus, type 2 was declared eradicated in 2015 (1,2). The use of trivalent oral poliovirus vaccine (tOPV; types 1, 2, and 3 Sabin strains) ceased in April 2016 via a 1-month ...
Jaume Jorba, Graham Tallis, Mary M. Alleman, Ajay Kumar Goel, Steven G. F. Wassilak, Eric Wiesen, Cara C. Burns, Jane Iber, Sharon A Greene, Ousmane M. Diop   +9 more
openaire   +3 more sources

Reversion of neurovirulent mutations, recombination and high intra‐host diversity in vaccine‐derived poliovirus excreted by patients with primary immune deficiency

Journal of Medical Virology
Patients with Primary immunodeficiency (PIDs) may be infected by Polioviruses (PVs), especially when vaccinated with live Oral Polio Vaccine before diagnosis.
I. Ben Salem, Haifa Khemiri, Oliver Drechsel, M. Arbi, Sindy Böttcher, N. Mekki, Ilhem Ben Fraj, Oussama Souiai, Mahrez Yahyaoui, Essia Ben Farhat, Z. Meddeb, H. Touzi, Imene Ben Mustapha, Alia Benkahla, M. Ouederni, M. Barbouche, Sabine Diedrich, H. Triki, S. Haddad-Boubaker   +18 more
semanticscholar   +1 more source

A RT-PCR method for selective amplification and phenotypic characterization of all three serotypes of Sabin-related polioviruses from viral mixtures

Memorias do Instituto Oswaldo Cruz, 2012
Outbreaks caused by vaccine-derived polioviruses are challenging the final eradication of paralytic poliomyelitis. Therefore, the surveillance of the acute flaccid paralysis cases based on poliovirus isolation and characterization remains an essential ...
Eliane Veiga da Costa, Renata de Mendonça Campos, Fernando Neto Tavares, Cátia Regina Valério Grégio, Fernanda Marcicano Burlandy, Edson Elias da Silva   +5 more
doaj   +1 more source

An outbreak of circulating vaccine derived poliovirus in Yemen, 2011-2012 [PDF]

International Journal of Infectious Diseases, 2014
Background: Yemen has been polio free since 2006. However, recently civil unrest and popular uprisings across the country arose with intermittent armed conflicts in the Northern governorates especially Sa’ada led to low routine immunization coverage and suspending supplementary immunization activities (SIAs).
openaire   +2 more sources

Polio eradication in Ghana: past, present, and future

Frontiers in Tropical Diseases
IntroductionGhana joined the Global Polio Eradication Initiative in 1996 to interrupt wild poliovirus transmission in the country. This was a collaborative effort by the Ghana Health Service (Disease Surveillance Department and the Expanded Program on ...
John Kofi Odoom, Dennis Odai Laryea, Nana Afia Asante Ntim, Keren Attiku, Michael Adjabeng, Ewurabena Oduma Duker, Comfort Nuamah Antwi, Emmanuel Gberbi, Isaac Baffoe-Nyarko, Patience Lartekai Adams, Angelina Evelyn Dickson, Jessica Dufie Boakye, Jude Yayra Mensah, Christabel Odoom, Sharon Ansong Bimpong, Deborah Odame, Gayheart Deladem Agboste, Nancy Odoom, Franklin Asiedu-Bekoe, Evangeline Obodai   +19 more
doaj   +1 more source

Identification Epitope on VP4 Protein of Senecavirus A Recognized by a Monoclonal Antibody

Animal Research and One Health, EarlyView.
This study aims to identify conserved antigenic epitopes on the SVA VP4 protein using monoclonal antibodies, providing valuable tools for further exploring its functions and developing detection methods. SVA VP4 protein was expressed in Escherichia coli and purified with High‐Affinity Ni‐Charged Resin FF.
Liang Meng, Xuyan Xiang, Xinyu Qi, Hanrong Zhou, Peiyu Xiao, Fandan Meng, Tongqing An, Haiwei Wang   +7 more
wiley   +1 more source