Results 21 to 30 of about 44,954 (187)

Persistent Transmission of Circulating Vaccine-Derived Poliovirus - Somalia, January 2017-March 2024. [PDF]

MMWR Morb Mortal Wkly Rep
Since the launch of the Global Polio Eradication Initiative in 1988, substantial progress has been made in the interruption of wild poliovirus (WPV) transmission worldwide: global eradication of WPV types 2 and 3 were certified in 2015 and 2019 ...
Mendes A, Mohamed GA, Derow M, Stehling-Ariza T, Mohamed A, Mengistu K, Bullard K, Akbar IE, Shukla H, Al Safadi M, Martinez M.   +10 more
europepmc   +2 more sources

The Origins and Risk Factors for Serotype-2 Vaccine-Derived Poliovirus Emergences in Africa During 2016-2019. [PDF]

J Infect Dis, 2023
Serotype 2 oral poliovirus vaccine (OPV2) can revert to regain wild-type neurovirulence and spread to cause emergences of vaccine-derived poliovirus (VDPV2). After its global withdrawal from routine immunization in 2016, outbreak response use has created
Gray EJ, Cooper LV, Bandyopadhyay AS, Blake IM, Grassly NC.   +4 more
europepmc   +2 more sources

Global epidemiology of vaccine-derived poliovirus 2016–2021: A descriptive analysis and retrospective case-control study [PDF]

EClinicalMedicine, 2022
Yi An Lai, Xin Chen, Mohana Kunasekaran, Bayzidur Rahman, C. Raina MacIntyre   +4 more
europepmc   +3 more sources

Outbreak Response to Circulating Vaccine-Derived Poliovirus in Three Northern Regions of Ghana, 2019. [PDF]

Biomed Res Int
Background: Circulating Vaccine-Derived Poliovirus Type 2 (cVDPV2) was isolated in sewage and later in stool samples from children with acute flaccid paralysis (AFP) in northern Ghana.
Odoom JK, Dzotse EK, Nii-Trebi NI, Opare D, Akyereko E, Attiku K, Duker EO, Eshun M, Boahene BB, Gberbi E, Houphouet EE, Diamenu S, Adjabeng M, Asamoah-Frimpong J, Ameme D, Opare JKL, Obodai E.   +16 more
europepmc   +2 more sources

Antisera-Neutralizing Capacity of a Highly Evolved Type 2 Vaccine-Derived Poliovirus from an Immunodeficient Patient. [PDF]

Viruses
Background: The serotype 2 oral poliovirus vaccine (OPV2) can revert to regain wild-type neurovirulence and spread, causing the emergence of vaccine-derived poliovirus (VDPV2) and immunodeficiency-related vaccine-derived polioviruses (iVDPVs).
Wu Y, Zhang R, Yuan G, He L, Dai X, Chuan H, Wang M, Liu J, Xu L, Liao G, Li W, Zhou J.   +11 more
europepmc   +2 more sources

Metagenomic sequencing, molecular characterization, and Bayesian phylogenetics of imported type 2 vaccine-derived poliovirus, Spain, 2021. [PDF]

Front Cell Infect Microbiol, 2023
Introduction In 2021, a type 2 vaccine-derived poliovirus (VDPV2) was isolated from the stool of a patient with acute flaccid paralysis (AFP) admitted to Spain from Senegal.
Fernandez-Garcia MD, Faye M, Diez-Fuertes F, Moreno-Docón A, Chirlaque-López MD, Faye O, Cabrerizo M.   +6 more
europepmc   +2 more sources

Environmental surveillance detects circulating vaccine-derived poliovirus type 2 that was undetected by acute flaccid paralysis surveillance in 2021 in Uganda. [PDF]

Arch Virol, 2023
The success of the global polio eradication initiative is threatened by the genetic instability of the oral polio vaccine, which can result in the emergence of pathogenic vaccine-derived polioviruses following prolonged replication in the guts of ...
Tushabe P, Bwogi J, Eliku JP, Aine F, Birungi M, Gaizi J, Nakabazzi L, Kabaliisa T, Turyahabwe I, Namuwulya P, Nanteza MB, Bukenya H, Kanyesigye C, Katushabe E, Ampeire I, Kisakye A, Bakamutumaho B, Byabamazima CR.   +17 more
europepmc   +2 more sources

Improvements of acute flaccid paralysis and measles surveillance performances in response to outbreak of circulating vaccine-derived poliovirus (2021-2022): the case of Southwest Ethiopia Region, Ethiopia. [PDF]

Pan Afr Med J
Introduction following the detection of vaccine-derived poliovirus in 2019 in Ethiopia, response activities have been conducted including strengthening disease surveillance activities.
Denegetu AW, Birru TG, Asemahaegn EW.
europepmc   +2 more sources

Response to back-to-back outbreaks of circulating vaccine-derived poliovirus type 2 in two nomadic pastoralist settlements in Oti Region, Ghana-2019. [PDF]

Arch Public Health, 2023
Background The global switch from trivalent oral poliovirus vaccine (OPV) to bivalent OPV in April 2016 without corresponding co-administration of inactivated poliovirus vaccine (IPV) until June 2018, created a cohort of poliovirus type 2 naïve children ...
Ameme DK, Yeboah YO, Odoom JK, Djokoto SK, Akyereko E, Mamudu A, Diwura M, Opare W, Avevor P, Diamenu S, Ohene SA, Kenu E, Asiedu-Bekoe F.   +12 more
europepmc   +2 more sources

Immunodeficiency-Related Vaccine-Derived Poliovirus (iVDPV) Excretion in an Infant with Severe Combined Immune Deficiency with Spillover to a Parent. [PDF]

Vaccines (Basel)
In order to maintain the polio eradication status, it has become evident that the surveillance of cases with acute flaccid paralysis and of environmental samples must be urgently supplemented with the surveillance of poliovirus excretions among ...
Mohanty MC, Govindaraj G, Ahmad M, Varose SY, Tatkare M, Shete A, Yadav S, Joshi Y, Yadav P, Sharma D, Kumar A, Verma H, Patil AP, Edavazhipurath A, Dhanasooraj D, Othayoth Kandy S, Puthenpurayil JM, Chakyar K, Melarcode Ramanan K, Madkaikar M.   +19 more
europepmc   +2 more sources