Poliovirus-Neutralizing Antibody Seroprevalence and Vaccine Habits in a Vaccine-Derived Poliovirus Outbreak Region in the Democratic Republic of Congo in 2018: The Impact on the Global Eradication Initiative. [PDF]
Despite the successes in wild-type polio eradication, poor vaccine coverage in the DRC has led to the occurrence of circulating vaccine-derived poliovirus outbreaks.
Halbrook M +19 more
europepmc +2 more sources
Update on Vaccine-Derived Poliovirus Outbreaks - Worldwide, January 2020-June 2021. [PDF]
As of May 1, 2016, use of oral poliovirus vaccine (OPV) type 2 for routine and supplementary immunization activities ceased after a synchronized global switch from trivalent OPV (tOPV; containing Sabin strain types 1, 2, and 3) to bivalent OPV (bOPV ...
Alleman MM +8 more
europepmc +2 more sources
Visualization of the Evolution and Transmission of Circulating Vaccine-Derived Poliovirus (cVDPV) Outbreaks in the African Region [PDF]
Since the creation of the Global Polio Eradication Initiative (GPEI) in 1988, significant progress has been made toward attaining a poliovirus-free world. This has resulted in the eradication of wild poliovirus (WPV) serotypes two (WPV2) and three (WPV3)
D. Collins Owuor +22 more
europepmc +3 more sources
Detection of vaccine-derived poliovirus type 2 from sewage samples and public health response, Poland, November to December 2024 [PDF]
In October and December 2024, circulating vaccine-derived poliovirus type 2 (cVDPV2) was detected from two wastewater samples in Poland during routine environmental surveillance.
Magdalena Wieczorek +8 more
europepmc +3 more sources
Detection of a Highly Divergent Type 3 Vaccine-Derived Poliovirus in a Child with a Severe Primary Immunodeficiency Disorder - Chongqing, China, 2022. [PDF]
Oral poliovirus vaccine (OPV) has proven to be highly effective in the global effort to eradicate poliomyelitis because of its ability to induce both humoral and intestinal immunity, ease of administration, and low cost (1).
Yao N +8 more
europepmc +2 more sources
Key Points Question Can the Sabin-strain of the inactivated poliovirus vaccine (IPV) be used in response to a circulating type 2 vaccine-derived poliovirus (VDPV2) event?
Yang H +31 more
europepmc +2 more sources
Detection of vaccine-derived poliovirus type-3 in sewage of Kathmandu Valley, Nepal
Enteroviruses include polioviruses, which are classified into three types: type 1, type 2, and type 3. The oral polio vaccine (OPV), which contains attenuated strains of these three types, has been pivotal in reducing polio incidence worldwide.
Rachana Mehta +4 more
doaj +2 more sources
Epidemiology of type 2 vaccine-derived poliovirus outbreaks between 2016 and 2020 [PDF]
The number and geographic breadth of circulating vaccine-derived poliovirus type 2 (cVDPV2) outbreaks detected after the withdrawal of type 2 containing oral polio vaccine (April 2016) have exceeded forecasts.Using Acute Flaccid Paralysis (AFP) investigations and environmental surveillance (ES) data from the Global Polio Laboratory Network, we ...
Macklin, GR +7 more
openaire +5 more sources
Detection of circulating vaccine-derived poliovirus type 2 (cVDPV2) in wastewater samples: a wake-up call, Finland, Germany, Poland, Spain, the United Kingdom, 2024 [PDF]
In 2024, circulating vaccine-derived poliovirus type 2 (cVDPV2) was detected in wastewater samples in Finland, Germany, Poland, Spain and the United Kingdom (UK).
Sindy Böttcher +15 more
europepmc +3 more sources
Evolution of a rare vaccine-derived multirecombinant poliovirus
Recombination is one of the mechanisms by which viral genomes evolve. A vaccine-derived multirecombinant poliovirus strain was isolated from a 5-month-old child with vaccine-associated paralytic poliomyelitis after oral poliovirus vaccine administration. The isolate had an S2/S1/S2/S1 primary genomic structure as revealed by restriction fragment length
Ioannis Karakasiliοtis +2 more
openalex +4 more sources

