Results 41 to 50 of about 9,622 (181)

Coordinated Response to Imported Vaccine-Derived Poliovirus Infection, Barcelona, Spain, 2019–2020 [PDF]

open access: yesEmerging Infectious Diseases, 2021
In 2019, the Public Health Agency of Barcelona, Spain, was notified of a vaccine-derived poliovirus infection. The patient had an underlying common variable immunodeficiency and no signs of acute flaccid paralysis. We describe the ongoing coordinated response to contain the infection, which included compassionate-use treatment with pocapavir.
Dolores Álamo-Junquera   +15 more
openaire   +5 more sources

First isolation of vaccine-derived poliovirus in Slovakia

open access: yesWeekly releases (1997–2007), 2005
In April 2003, a vaccine-derived poliovirus Sabin 2 (VDPV) was isolated from sewage water in Vrakuna, a Bratislava city district in western ...
Eva, Máderová   +4 more
openaire   +2 more sources

Circulating vaccine-derived poliovirus: a menace to the end game of polio eradication

open access: yesGlobalization and Health, 2020
The World Health Organisation Western Pacific Region countries were declared free of polio in 2000 until a polio outbreak involving 305 cases occurred in Indonesia in 2006.
Long Chiau Ming   +4 more
doaj   +1 more source

Evolution of a rare vaccine-derived multirecombinant poliovirus

open access: yesJournal of General Virology, 2005
Recombination is one of the mechanisms by which viral genomes evolve. A vaccine-derived multirecombinant poliovirus strain was isolated from a 5-month-old child with vaccine-associated paralytic poliomyelitis after oral poliovirus vaccine administration. The isolate had an S2/S1/S2/S1 primary genomic structure as revealed by restriction fragment length
Ioannis, Karakasiliotis   +2 more
openaire   +2 more sources

Achieving High Poliovirus Antibody Seroprevalence in Areas at Risk of Vaccine-Derived Poliovirus Transmission—Niger Experience [PDF]

open access: yesOpen Forum Infectious Diseases, 2021
Abstract Background Outbreaks of vaccine-derived poliovirus type 2 (VDPV2) continue to expand across Africa. We conducted a serological survey of polio antibodies in high–polio risk areas of Niger to assess risk of poliovirus outbreaks. Methods
Ousmane, Sani   +8 more
openaire   +2 more sources

Managing the risk of circulating vaccine-derived poliovirus during the endgame: oral poliovirus vaccine needs [PDF]

open access: yesBMC Infectious Diseases, 2015
The Global Polio Eradication Initiative plans for coordinated cessation of oral poliovirus vaccine (OPV) use, beginning with serotype 2-containing OPV (i.e., OPV2 cessation) followed by the remaining two OPV serotypes (i.e., OPV13 cessation). The risk of circulating vaccine-derived poliovirus (cVDPV) outbreaks after OPV cessation of any serotype ...
Duintjer Tebbens, Radboud J.   +1 more
openaire   +2 more sources

Prolonged Excretion of Poliovirus among Individuals with Primary Immunodeficiency Disorder: An Analysis of the World Health Organization Registry

open access: yesFrontiers in Immunology, 2017
Individuals with primary immunodeficiency disorder may excrete poliovirus for extended periods and will constitute the only remaining reservoir of virus after eradication and withdrawal of oral poliovirus vaccine.
Grace Macklin   +31 more
doaj   +1 more source

Vaccine-related poliovirus shedding in trivalent polio vaccine and human immunodeficiency virus status: analysis from under five children

open access: yesBMC Research Notes, 2017
Background Poliomyelitis is an acute viral infection caused by poliovirus and transmitted via the fecal–oral route. The causative agent is one of the three serotypes of poliovirus (serotypes 1, 2, 3) that differ slightly in capsid protein.
Joanne Hassan   +6 more
doaj   +1 more source

The detection of 3 ambiguous type 2 vaccine-derived polioviruses (VDPV2s) in Uganda

open access: yesVirology Journal, 2018
Background The Oral Polio Vaccine (OPV or Sabin) is genetically unstable and may mutate to form vaccine-derived polioviruses (VDPVs). Methods In 2014, two VDPVs type 2 were identified during routine surveillance of acute flaccid paralysis (AFP) cases ...
Mary Bridget Nanteza   +9 more
doaj   +1 more source

Determination of antigenic properties of vaccine derived poliovirus strains

open access: yesVaccine, 2010
In this study, the immunity level of the southern Greek population in the 1-10-year, 11-20-year, 21-30-year and 31-40-year age groups with regard to Sabin vaccine strains and a collection of 11 recombinant and three non-recombinant poliovirus vaccine strains was determined.
Pliaka, V.   +7 more
openaire   +3 more sources

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