Results 81 to 90 of about 44,954 (187)

Long-Term Excretion of Vaccine-Derived Poliovirus by a Healthy Child [PDF]

Journal of Virology, 2004
ABSTRACT A child was found to be excreting type 1 vaccine-derived poliovirus (VDPV) with a 1.1% sequence drift from Sabin type 1 vaccine strain in the VP1 coding region 6 months after he was immunized with oral live polio vaccine. Seventeen type 1 poliovirus isolates were recovered from stools taken from this child during the following 4 ...
Catherine Fitzharris, William W. Hall, Karina Butler, Philip D. Minor, Gill Cooper, Gráinne Tuite, Javier Martin, Glynis Dunn, Kofi Odoom, Nicola Hopewell   +9 more
openaire   +3 more sources

Detection of vaccine-derived poliovirus circulation by environmental surveillance in the absence of clinical cases [PDF]

Human Vaccines & Immunotherapeutics, 2021
On August 25, 2019, the Noguchi Memorial Institute for Medical Research notified the confirmation of a circulating-vaccine-derived poliovirus type-2 (cVDPV2) from the Agbogbloshie environmental surveillance (AES) site, in the Greater Accra Region.
John Kofi Odoom, Evangeline Obodai, Gifty Boateng, Stanley Diamenu, Keren Attiku, Patrick Avevor, Ewurabena Duker, Bismarck Boahene, Miriam Eshun, Emmanuel Gberbie, Joseph Kwadwo Larbi Opare   +10 more
openaire   +3 more sources

Assessment of poliovirus antibody seroprevalence in high risk areas for vaccine derived poliovirus transmission in Madagascar [PDF]

Heliyon, 2018
Vaccine-derived polioviruses (VDPV) outbreaks typically occur in areas of low poliovirus immunity. Madagascar successfully eradicated wild poliovirus in 1997; however, multiple VDPV outbreaks have occurred since then, and numerous vaccination campaigns have been carried out to control the VDPV outbreaks. We conducted a survey of poliovirus neutralizing
M. Steven Oberste, Roland W. Sutter, Richter Razafindratsimandresy, William C. Weldon, Ondrej Mach, Barivola Bernardson, Jean-Michel Heraud   +6 more
openaire   +3 more sources

Prolonged Excretion of Poliovirus among Individuals with Primary Immunodeficiency Disorder: An Analysis of the World Health Organization Registry

Frontiers in Immunology, 2017
Individuals with primary immunodeficiency disorder may excrete poliovirus for extended periods and will constitute the only remaining reservoir of virus after eradication and withdrawal of oral poliovirus vaccine.
Grace Macklin, Yi Liao, Yi Liao, Marina Takane, Kathleen Dooling, Stuart Gilmour, Ondrej Mach, Olen M. Kew, Olen M. Kew, Roland W. Sutter, The iVDPV Working Group, Ousmane Diop, Nicksy Gumede Moeletsi, Raffaella Williams, Mohamed Seghier, Francis Delpeyroux, Gloria Rey Benito, Maria Cecilia Freire, Cara Burns, Humayun Asghar, Salman Sharif, Jagadish Deshpande, Shohreh Shahmahmoodi, Henda Triki, Laila E Bassioni, Amina Al-Jardani, Eugene Merav Weil Gavrilin, Javier Martín, Sirima Pattamadilok, Sunethra Gunasena, Yan Zhang, Wenbo Xu   +31 more
doaj   +1 more source

Vaccine-related poliovirus shedding in trivalent polio vaccine and human immunodeficiency virus status: analysis from under five children

BMC Research Notes, 2017
Background Poliomyelitis is an acute viral infection caused by poliovirus and transmitted via the fecal–oral route. The causative agent is one of the three serotypes of poliovirus (serotypes 1, 2, 3) that differ slightly in capsid protein.
Joanne Hassan, Laura Wangai, Peter Borus, Christopher Khayeka–Wandabwa, Lucy Wanja Karani, Mercy Kithinji, Michael Kiptoo   +6 more
doaj   +1 more source

Managing the risk of circulating vaccine-derived poliovirus during the endgame: oral poliovirus vaccine needs [PDF]

BMC Infectious Diseases, 2015
The Global Polio Eradication Initiative plans for coordinated cessation of oral poliovirus vaccine (OPV) use, beginning with serotype 2-containing OPV (i.e., OPV2 cessation) followed by the remaining two OPV serotypes (i.e., OPV13 cessation). The risk of circulating vaccine-derived poliovirus (cVDPV) outbreaks after OPV cessation of any serotype ...
Kimberly M. Thompson, Radboud J. Duintjer Tebbens   +1 more
openaire   +3 more sources

The detection of 3 ambiguous type 2 vaccine-derived polioviruses (VDPV2s) in Uganda

Virology Journal, 2018
Background The Oral Polio Vaccine (OPV or Sabin) is genetically unstable and may mutate to form vaccine-derived polioviruses (VDPVs). Methods In 2014, two VDPVs type 2 were identified during routine surveillance of acute flaccid paralysis (AFP) cases ...
Mary Bridget Nanteza, Barnabas Bakamutumaho, Annet Kisakye, Prossy Namuwulya, Henry Bukenya, Edson Katushabe, Josephine Bwogi, Charles Rutebarika Byabamazima, Raffaella Williams, Nicksy Gumede   +9 more
doaj   +1 more source

Preventing Vaccine-Derived Poliovirus Emergence during the Polio Endgame

PLOS Pathogens, 2016
Reversion and spread of vaccine-derived poliovirus (VDPV) to cause outbreaks of poliomyelitis is a rare outcome resulting from immunisation with the live-attenuated oral poliovirus vaccines (OPVs). Global withdrawal of all three OPV serotypes is therefore a key objective of the polio endgame strategic plan, starting with serotype 2 (OPV2) in April 2016.
Margarita Pons-Salort, Cara C. Burns, Hil Lyons, Isobel M. Blake, Hamid Jafari, M. Steven Oberste, Olen M. Kew, Nicholas C. Grassly   +7 more
openaire   +7 more sources

Long-Term Circulation of Vaccine-Derived Poliovirus That Causes Paralytic Disease [PDF]

Journal of Virology, 2002
ABSTRACT Successful implementation of the global poliomyelitis eradication program raises the problem of vaccination against poliomyelitis in the posteradication era. One of the options under consideration envisions completely stopping worldwide the use of the Sabin vaccine.
Olga Ivanova, Eremeeva Tp, Maria L. Yakovenko, Vadim I. Agol, Vadim I. Agol, Konstantin Chumakov, Ekaterina A. Korotkova, Elena Cherkasova, Elena Cherkasova   +8 more
openaire   +3 more sources

A Survey to Assess Serological Prevalence of Poliovirus Antibodies in Areas With High-Risk for Vaccine-Derived Poliovirus Transmission in Chad [PDF]

Journal of the Pediatric Infectious Diseases Society, 2021
Abstract Background World Health Organization African region is wild poliovirus-free; however, outbreaks of vaccine-derived poliovirus type 2 (VDPV2) continue to expand across the continent including in Chad.
Richelot Ayangma, Eric Wiesen, Tess Palmer, Kadidja Gamougam, Ondrej Mach, Dhoud Samba, Visalakshi Jeyaseelan, Aissata Diaha, Kathryn A V Jones, Norbert Gnakub Soke, Benoit Ntezayabo, Bernardo A Mainou, Samuel Okiror   +12 more
openaire   +2 more sources