Results 61 to 70 of about 1,325,849 (308)

Systems serology-based comparison of humoral immune responses induced by liposome or aluminum hydroxide adjuvanted SARS-CoV-2 spike protein

Scientific Reports
Adjuvants play a crucial role in enhancing vaccine-induced immune responses by shaping the magnitude and quality of humoral and cellular immunity.
Soo Ji Kim, Taewoo Kim, Satyanarayana Bejjani, Mi Sun Kim, Jung Hyuk Lee, Yuna Shin, Sun-Je Woo, Beom Min Cheon, Doyoung Kim, Sumin Lee, Eunjin Cho, Junhyeon Lee, Ruchirkumar Pansuriya, Wook-Jin Park, Gaurav Pandey, Ravi Ganapathy, Jung-Ah Choi, Ju Yeon Park, Deok Ryun Kim, Cheol-Heui Yun, Jae Seung Yang, Byoung-Shik Shim, Manki Song   +22 more
doaj   +1 more source

Nuclear-resident RIG-I senses viral replication inducing antiviral immunity

Nature Communications, 2018
RIG-I senses cytoplasmic viral RNA, resulting in induction of an antiviral response. Here, the authors identify nuclear RIG-I and show that it binds nuclear influenza A virus RNA, resulting in a cooperative interferon induction along with its cytoplasmic
GuanQun Liu, Yao Lu, Sathya N. Thulasi Raman, Fang Xu, Qi Wu, Zhubing Li, Robert Brownlie, Qiang Liu, Yan Zhou   +8 more
doaj   +1 more source

Development of flow cytometry based adherence assay for Neisseria gonorrhoeae using 5′-carboxyfluorosceinsuccidyl ester

BMC Microbiology, 2019
Background Neisseria gonorrhoeae is an obligate human pathogen and its adherence to host cells is essential for its pathogenesis. Gonococcal adherence assays are based on the enumeration of bacteria attached to human cells on solid media.
Sidharath Dev Thakur, Milan Obradovic, Jo-Anne R. Dillon, Siew Hon Ng, Heather L. Wilson   +4 more
doaj   +1 more source

Vaccines: Propaganda and Practice [PDF]

, 2008
Vaccines are a cost effective, time tested means of reducing morbidity and mortality. As more and more new vaccines are introduced and more diseases come under the purview of ‘vaccination net’, the routine immunization program is sidelined.\ud This is ...
Baliga, Shantharam B, Baliga, Shrikala
core   +1 more source

Infection-acquired versus vaccine-acquired immunity in an SIRWS model [PDF]

, 2017
Despite high vaccine coverage, pertussis has re-emerged as a public health concern in many countries. One hypothesis posed for re-emergence is the waning of immunity.
Campbell, Patricia T, Frascoli, Federico, Hughes, Barry D, Leung, Tiffany, McCaw, James M   +4 more
core   +2 more sources

Prevalence of Systemic Lupus Erythematosus in Australia, 2010–2022: A Population‐Based Study Using Linked National Administrative Health Data

Arthritis Care &Research, Accepted Article.
Objectives Systemic lupus erythematosus (SLE) is a heterogenous inflammatory condition, with widely varying global prevalence estimates. Frequency of SLE in the general population of Australia has been reported to be notably lower than contemporary estimates in countries such as the US or UK at 19‐39 per 100,000 as opposed to 65‐97 per 100,000.
Lucinda Roper, Rachel Black, Joanna Tieu, Winnie Chen, Matthew Parker, Catherine Hill, Natasha Nassar, Mandana Nikpour   +7 more
wiley   +1 more source

A forecast of typhoid conjugate vaccine introduction and demand in typhoid endemic low- and middle-income countries to support vaccine introduction policy and decisions

Human Vaccines & Immunotherapeutics, 2017
A Typhoid Conjugate Vaccine (TCV) is expected to acquire WHO prequalification soon, which will pave the way for its use in many low- and middle-income countries where typhoid fever is endemic.
Vittal Mogasale, Enusa Ramani, Il Yeon Park, Jung Seok Lee   +3 more
doaj   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Prevalence of human filovirus infections in sub-Saharan Africa: A systematic review and meta-analysis protocol

Systematic Reviews
Background Recent outbreaks of Ebola virus disease (EVD) and Marburg virus disease (MVD) in sub-Saharan Africa illustrate the need to better understand animal reservoirs, burden of disease, and human transmission of filoviruses.
Christopher S. Semancik, Christopher L. Cooper, Thomas S. Postler, Matt Price, Heejin Yun, Marija Zaric, Monica Kuteesa, Nina Malkevich, Andrew Kilianski, Swati B. Gupta, Suzanna C. Francis   +10 more
doaj   +1 more source

Coadministration of 13-valent pneumococcal conjugate and quadrivalent inactivated influenza vaccines in adults previously immunized with polysaccharide pneumococcal vaccine 23: a randomized clinical trial

Human Vaccines & Immunotherapeutics, 2019
Immune responses to 13-valent pneumococcal conjugate vaccine (PCV13) and quadrivalent inactivated influenza vaccine (QIV) in older adults may vary with coadministration and previous pneumococcal polysaccharide vaccination.
Allison R. Thompson, Nicola P. Klein, H. Jackson Downey, Scott Patterson, Vani Sundaraiyer, Wendy Watson, Keri Clarke, Kathrin U. Jansen, Shite Sebastian, William C. Gruber, Daniel A. Scott, Beate Schmöele-Thoma   +11 more
doaj   +1 more source