Results 31 to 40 of about 596,848 (310)

Repurposing of Miltefosine as an Adjuvant for Influenza Vaccine [PDF]

open access: yes, 2020
We previously reported that topical imiquimod can improve the immunogenicity of the influenza vaccine. This study investigated another FDA-approved drug, miltefosine (MTF), as a vaccine adjuvant.
Chu, H   +27 more
core   +1 more source

LDH as an adjuvant makes Brucella outer-membrane vesicles and outer-membrane vesicle-associated proteins highly protective in mice [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2023
Objective(s): Existing Brucella vaccines are attenuated and can cause vaccine-associated brucellosis; and these safety concerns have affected their application.
Xiaoyu Deng   +8 more
doaj   +1 more source

Lipopolysaccharide Derived From the Lymphoid-Resident Commensal Bacteria Alcaligenes faecalis Functions as an Effective Nasal Adjuvant to Augment IgA Antibody and Th17 Cell Responses

open access: yesFrontiers in Immunology, 2021
Alcaligenes spp., including A. faecalis, is a gram-negative facultative bacterium uniquely residing inside the Peyer’s patches. We previously showed that A.
Yunru Wang   +24 more
doaj   +1 more source

Classification of the Occurrence of Dyslipidemia Based on Gut Bacteria Related to Barley Intake

open access: yesFrontiers in Nutrition, 2022
Barley is a grain rich in β-glucan, a soluble dietary fiber, and its consumption can help maintain good health and reduce the risk of metabolic disorders, such as dyslipidemia.
Satoko Maruyama   +22 more
doaj   +1 more source

T cell responses to the RTS,S/AS01(E) and RTS,S/AS02(D) malaria candidate vaccines administered according to different schedules to Ghanaian children. [PDF]

open access: yes, 2011
BACKGROUND: The Plasmodium falciparum pre-erythrocytic stage candidate vaccine RTS,S is being developed for protection of young children against malaria in sub-Saharan Africa.
Osei-Kwakye, Kingsley   +97 more
core   +1 more source

Host- and Microbe-Dependent Dietary Lipid Metabolism in the Control of Allergy, Inflammation, and Immunity

open access: yesFrontiers in Nutrition, 2019
The intestine is the largest immune organ in the body, provides the first line of defense against pathogens, and prevents excessive immune reactions to harmless or beneficial non-self-materials, such as food and intestinal bacteria.
Azusa Saika   +7 more
doaj   +1 more source

Model for predicting age-dependent safety and immunomodulatory effects of STING ligands in non-human primates

open access: yesMolecular Therapy: Methods & Clinical Development, 2023
Stimulator of interferon genes (STING) is a cytoplasmic dinucleotide sensor used as an immunomodulatory agent for cancer treatment. The efficacy of the STING ligand (STING-L) against various tumors has been evaluated in mouse models; however, its safety ...
Shokichi Takahama   +5 more
doaj   +1 more source

Adjuvants for Coronavirus Vaccines [PDF]

open access: yesFrontiers in Immunology, 2020
Vaccine development utilizing various platforms is one of the strategies that has been proposed to address the coronavirus disease 2019 (COVID-19) pandemic. Adjuvants are critical components of both subunit and certain inactivated vaccines because they induce specific immune responses that are more robust and long-lasting.
Zhihui Liang   +15 more
openaire   +3 more sources

Vaccination with the surface proteins MUL_2232 and MUL_3720 of Mycobacterium ulcerans induces antibodies but fails to provide protection against Buruli ulcer [PDF]

open access: yes, 2016
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a chronic ulcerative neglected tropical disease of the skin and subcutaneous tissue that is most prevalent in West African countries. M.
Miriam Bolz   +35 more
core   +2 more sources

Adjuvanted influenza vaccines [PDF]

open access: yesHuman Vaccines & Immunotherapeutics, 2012
The search for adjuvants has been stimulated by the need to ensure greater protection against influenza among subjects who show a reduced immune response to conventional influenza vaccines. Aluminum salts have long been used but are not considered satisfactory.
N. Principi   +1 more
openaire   +7 more sources

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