Results 11 to 20 of about 86,997 (265)

Overcoming Aging-Associated Poor Influenza Vaccine Responses with CpG 1018 Adjuvant [PDF]

open access: yes, 2022
Aging is associated with diminished immune system function, which renders old people vulnerable to influenza infection and also less responsive to influenza vaccination.
Kang, Xinliang   +7 more
core   +1 more source

The chemotherapeutic agent DMXAA as a unique IRF3-dependent type-2 vaccine adjuvant [PDF]

open access: yes, 2013
5,6-Dimethylxanthenone-4-acetic acid (DMXAA), a potent type I interferon (IFN) inducer, was evaluated as a chemotherapeutic agent in mouse cancer models and proved to be well tolerated in human cancer clinical trials.
Cevayir Coban   +23 more
core   +1 more source

Repurposing of Miltefosine as an Adjuvant for Influenza Vaccine [PDF]

open access: yes, 2020
We previously reported that topical imiquimod can improve the immunogenicity of the influenza vaccine. This study investigated another FDA-approved drug, miltefosine (MTF), as a vaccine adjuvant.
Chu, H   +27 more
core   +1 more source

T cell responses to the RTS,S/AS01(E) and RTS,S/AS02(D) malaria candidate vaccines administered according to different schedules to Ghanaian children. [PDF]

open access: yes, 2011
BACKGROUND: The Plasmodium falciparum pre-erythrocytic stage candidate vaccine RTS,S is being developed for protection of young children against malaria in sub-Saharan Africa.
Osei-Kwakye, Kingsley   +97 more
core   +1 more source

Effect of incorporating different concentrations of palm oil as adjuvant in fish vaccine [PDF]

open access: yes, 2018
Adjuvants play important role in vaccine efficacy due to the slow release that leads to prolong immune response. This study determines the advantage of palm oil as adjuvant in the newly developed feed-based killed vaccine against streptococcosis.
Hashim, Shahidan   +9 more
core   +1 more source

Vaccination with the surface proteins MUL_2232 and MUL_3720 of Mycobacterium ulcerans induces antibodies but fails to provide protection against Buruli ulcer [PDF]

open access: yes, 2016
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a chronic ulcerative neglected tropical disease of the skin and subcutaneous tissue that is most prevalent in West African countries. M.
Miriam Bolz   +26 more
core   +1 more source

Protective antiviral immune responses to pseudorabies virus induced by DNA vaccination using dimethyldioctadecylammonium bromide as an adjuvant

open access: yes, 2002
To enhance the efficacy of a DNA vaccine against pseudorabies virus (PRV), we evaluated the adjuvant properties of plasmids coding for gamma interferon or interleukin-12, of CpG immunostimulatory motifs, and of the conventional adjuvants ...
Eddie G. te Lintelo   +26 more
core   +1 more source

Transient Facial Nerve Paralysis (Bell's Palsy) following Intranasal Delivery of a Genetically Detoxified Mutant of Escherichia coli Heat Labile Toxin.

open access: yes, 2009
BACKGROUND: An association was previously established between facial nerve paralysis (Bell's palsy) and intranasal administration of an inactivated influenza virosome vaccine containing an enzymatically active Escherichia coli Heat Labile Toxin (LT ...
Kromann Ingrid   +35 more
core   +1 more source

Adjuvanted influenza vaccines

open access: yesExpert Review of Vaccines, 2013
Influenza is one of the most common causes of human morbidity and mortality that is preventable by vaccination. Immunization with available vaccines provides incomplete protection against illness caused by influenza virus, especially in high-risk groups such as the elderly and young children.
Orli, Even-Or   +4 more
openaire   +2 more sources

Vaccination with complete adjuvant-added inactivated virus vaccine of Japanese encephalitis to swine, rabbits and chicks for preventing viremia (epidemiological study on Japanese encephalitis 25)

open access: yes, 1969
As a step towards the elimination of Japanese encephalitis virus in natural surroundings, we inoculated pigs, rabbits and chicks with inactivated Japanese encephalitis vaccine supplemented with complete or incomplete Freund's adjuvant twice at one-week ...
Nagao, Yutaka   +3 more
core   +1 more source

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