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Rational Vaccine Design in the Time of COVID-19
Cell Host and Microbe, 2020 As scientists consider SARS-CoV-2 vaccine design, we discuss problems that may be encountered and how to tackle them by what we term “rational vaccine design.” We further discuss approaches to pan-coronavirus vaccines.
D. Burton, L. Walker
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From Structural Studies to HCV Vaccine Design
Viruses, 2021 Hepatitis C virus (HCV) is a serious and growing public health problem despite recent developments of antiviral therapeutics. To achieve global elimination of HCV, an effective cross-genotype vaccine is needed.
Itai Yechezkel, M. Law, N. Tzarum
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, 2020 Tuberculosis still claims more lives than any other pathogen, and a vaccine better than BCG is urgently needed. One of the challenges for novel TB vaccines is to protect against all Mycobacterium tuberculosis lineages, including the most virulent ones ...
권기웅, 신성재
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Computational epitope-based vaccine design with bioinformatics approach; a review
HeliyonThe significance of vaccine development has gained heightened importance in light of the COVID-19 pandemic. In such critical circumstances, global citizens anticipate researchers in this field to swiftly identify a vaccine candidate to combat the ...
Esmaeil Roohparvar Basmenj +7 more
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Vaccine Design and Vaccination Strategies against Rickettsiae [PDF]
Vaccines, 2021 Rickettsioses are febrile, potentially lethal infectious diseases that are a serious health threat, especially in poor income countries. The causative agents are small obligate intracellular bacteria, rickettsiae. Rickettsial infections are emerging worldwide with increasing incidence and geographic distribution.
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Open Biology, 2023 Buruli ulcer (BU) is a neglected tropical disease. It is caused by the bacterium Mycobacterium ulcerans and is characterized by skin lesions. Several studies were performed testing the Bacillus Calmette-Guérin (BCG) vaccine in human and animal models and
Tamara Z. Ishwarlall +5 more
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Bionanotechnology for vaccine design
Current Opinion in Biotechnology, 2018 There have been significant advances in the design of nanostructured scaffolds for eliciting robust immune responses. One method to produce strong immune responses is to emulate the appearance of a pathogen. Since pathogens such as viruses and bacteria often display multiple copies of ligands on their surfaces, the immune system is particularly ...
Steven, Frey +3 more
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Primary and booster immune responses to SA14-14-2 Japanese encephalitis vaccine in Korean infants
, 1999 Attenuated SA14-14-2 Japanese encephalitis (JE) vaccine has been administered safely and effectively to more than 100 million children in China since 1988 and recently, licensure of the vaccine in Korea has been sought.
박민수
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Current Challenges in the Identification of Pre-Erythrocytic Malaria Vaccine Candidate Antigens
Frontiers in Immunology, 2020 Plasmodium spp.-infected mosquitos inject sporozoites into the skin of a mammalian host during a blood meal. These enter the host's circulatory system and establish an infection in the liver.
Paulo Bettencourt
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Personalized cancer vaccine design using AI-powered technologies
Frontiers in ImmunologyImmunotherapy has ushered in a new era of cancer treatment, yet cancer remains a leading cause of global mortality. Among various therapeutic strategies, cancer vaccines have shown promise by activating the immune system to specifically target cancer ...
Anant Kumar +4 more
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