Results 31 to 40 of about 26,123,489 (353)

Malaria vaccine research and development: the role of the WHO MALVAC committee. [PDF]

open access: yes, 2013
The WHO Malaria Vaccine Advisory Committee (MALVAC) provides advice to WHO on strategic priorities, activities and technical issues related to global efforts to develop vaccines against malaria.
Vasee S Moorthy   +9 more
core   +1 more source

Designing Tomorrow's Vaccines [PDF]

open access: yesNew England Journal of Medicine, 2013
Vaccines are some of the most cost-effective treatments in medicine. This article reviews new strategies being applied to develop vaccines for diseases that have not been susceptible to this therapeutic approach.
openaire   +2 more sources

Vaccine Design: An Introduction

open access: yes, 2023
Vaccines are the most successful and cost-effective medical interventions available to fight infectious diseases. They consist of biological preparations that are capable of stimulating the immune system to confer protective immunity against a particular harmful pathogen/agent. Vaccine design and development have evolved through the years.
Fiyouzi, Tara, Reche, Pedro A
openaire   +3 more sources

Method to identify efficiently cleaved, membrane-bound, functional HIV-1 (Human Immunodeficiency Virus-1) envelopes

open access: yesMethodsX, 2019
An ideal vaccine against HIV-1 will specifically elicit bNAbs (broadly neutralizing antibodies) which can cross-neutralize a wide spectrum of circulating viral strains belonging to different clades.
Sweety Samal   +2 more
doaj   +1 more source

Computational Design of a Chimeric Vaccine against Plesiomonas shigelloides Using Pan-Genome and Reverse Vaccinology

open access: yes, 2022
The swift emergence of antibiotic resistance (AR) in bacterial pathogens to make themselves adaptable to changing environments has become an alarming health issue. To prevent AR infection, many ways can be accomplished such as by decreasing the misuse of
Hassan, Muhammad   +17 more
core   +1 more source

COVID-19 coronavirus vaccine design using reverse vaccinology and machine learning

open access: yesbioRxiv, 2020
To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 coronavirus. Our literature and clinical trial survey showed that the whole virus,
E. Ong, Mei U. Wong, A. Huffman, Y. He
semanticscholar   +1 more source

Design of Multi-Epitope Vaccine for Staphylococcus saprophyticus: Pan-Genome and Reverse Vaccinology Approach

open access: yes, 2022
Staphylococcus saprophyticus is a Gram-positive coccus responsible for the occurrence of cystitis in sexually active, young females. While effective antibiotics against this organism exist, resistant strains are on the rise.
Sarosh, Nida   +23 more
core   +1 more source

Immunoinformatics for Novel Multi-Epitope Vaccine Development in Canine Parvovirus Infections

open access: yesBiomedicines, 2023
Canine parvovirus (CPV-2) is one of the most important pathogens of dogs of all ages, causing pandemic infections that are characterized by fatal hemorrhagic enteritis. The CPV-2 vaccine is recommended as a core vaccine for pet animals.
Bashudeb Paul   +16 more
doaj   +1 more source

The marginal willingness-to-pay for attributes of a hypothetical HIV vaccine [PDF]

open access: yes, 2012
This paper estimates the marginal willingness-to-pay for attributes of a hypothetical HIV vaccine using discrete choice modeling. We use primary data from 326 respondents from Bangkok and Chiang Mai, Thailand, in 2008–2009, selected using purposive ...
Newman, Peter A.   +15 more
core   +1 more source

Development of a bivalent conjugate vaccine candidate against rotaviral diarrhea and tuberculosis using polysaccharide from Mycobacterium tuberculosis conjugated to ΔVP8* protein from rotavirus

open access: yes, 2021
Conjugation of carbohydrate antigens with a carrier protein is a clinically proven strategy to overcome the poor immunogenicity of bacterial polysaccharide.
조상래   +8 more
core   +1 more source

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