Results 21 to 30 of about 9,828,326 (308)

Design of Multi-Epitope Vaccine for Staphylococcus saprophyticus: Pan-Genome and Reverse Vaccinology Approach

open access: yes, 2022
Staphylococcus saprophyticus is a Gram-positive coccus responsible for the occurrence of cystitis in sexually active, young females. While effective antibiotics against this organism exist, resistant strains are on the rise.
Sarosh, Nida   +23 more
core   +1 more source

Immunoinformatics for Novel Multi-Epitope Vaccine Development in Canine Parvovirus Infections

open access: yesBiomedicines, 2023
Canine parvovirus (CPV-2) is one of the most important pathogens of dogs of all ages, causing pandemic infections that are characterized by fatal hemorrhagic enteritis. The CPV-2 vaccine is recommended as a core vaccine for pet animals.
Bashudeb Paul   +16 more
doaj   +1 more source

Architects of folding, editors of immunity: the strategic use of N-glycans in vaccine design [PDF]

open access: yesFrontiers in Immunology
Sofia Orioli   +6 more
doaj   +2 more sources

Preclinical assessment of a new live attenuated Mycobacterium tuberculosis Beijing-based vaccine for tuberculosis

open access: yes, 2020
Tuberculosis still claims more lives than any other pathogen, and a vaccine better than BCG is urgently needed. One of the challenges for novel TB vaccines is to protect against all Mycobacterium tuberculosis lineages, including the most virulent ones ...
권기웅, 신성재
core   +1 more source

Heterogeneity in malaria exposure and vaccine response: implications for the interpretation of vaccine efficacy trials. [PDF]

open access: yes, 2010
BACKGROUND: Phase III trials of the malaria vaccine, RTS, S, are now underway across multiple sites of varying transmission intensity in Africa. Heterogeneity in exposure, vaccine response and waning of efficacy may bias estimates of vaccine efficacy ...
Michael T White   +11 more
core   +1 more source

Lipid Nanoparticles Potentiate CpG-Oligodeoxynucleotide-Based Vaccine for Influenza Virus

open access: yesFrontiers in Immunology, 2020
Current influenza vaccines are generally effective against highly similar (homologous) strains, but their effectiveness decreases markedly against antigenically mismatched (heterologous) strains. One way of developing a universal influenza vaccine with a
Seiki Shirai   +16 more
doaj   +1 more source

Exploring whole proteome to contrive multi-epitope-based vaccine for NeoCoV: An immunoinformtics and in-silico approach

open access: yesFrontiers in Immunology, 2022
Neo-Coronavirus (NeoCoV) is a novel Betacoronavirus (β-CoVs or Beta-CoVs) discovered in bat specimens in South Africa during 2011. The viral sequence is highly similar to Middle East Respiratory Syndrome, particularly that of structural proteins.
Shahkaar Aziz   +8 more
doaj   +1 more source

Designing Tomorrow's Vaccines [PDF]

open access: yesNew England Journal of Medicine, 2013
Vaccines are some of the most cost-effective treatments in medicine. This article reviews new strategies being applied to develop vaccines for diseases that have not been susceptible to this therapeutic approach.
openaire   +2 more sources

cGAMP the travelling messenger

open access: yesFrontiers in Immunology, 2023
2’3’-cGAMP is a key molecule in the cGAS-STING pathway. This cyclic dinucleotide is produced by the cytosolic DNA sensor cGAS in response to the presence of aberrant dsDNA in the cytoplasm which is associated with microbial invasion or cellular damage. 2’
Henry T. W. Blest, Lise Chauveau
doaj   +1 more source

Viroinformatics investigation of B-cell epitope conserved region in SARS-CoV-2 lineage B.1.1.7 isolates originated from Indonesia to develop vaccine candidate against COVID-19 [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2021
Context: SARS-CoV-2, a member of family Coronaviridae and the causative agent of COVID-19, is a virus which is transmitted to human and other mammals. Aims: To analyze the B-cell epitope conserved region and viroinformatics-based study of the SARS-CoV-
Arif N. M. Ansori   +13 more
doaj  

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